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Characterization of therapy-related acute myeloid leukemia : increasing incidence and prognostic implications

Studies of therapy-related AML (t-AML) are usually performed in selected cohorts and reliable incidence rates are lacking. In this study, we characterized, defined the incidence over time and studied prognostic implications in all t-AML patients diagnosed in Sweden between 1997 and 2015. Data were retrieved from nationwide population-based registries. In total, 6,779 AML patients were included in

Swedish journalists' perceptions of legal protection against unlawful online harassment

This study examined journalists' perceptions regarding the legal system's ability to protect them against online harassment. By utilizing open-ended survey responses from respondents with varying levels of trust in the legal system, the findings suggested a need for increased technical proficiency, resources, and priority within the legal system to adequately address the issue. Additionally, a rec

A molecular dynamics study on the influence of vacancies and interstitial helium on mechanical properties of tungsten

Tungsten is a prime candidate material for use in plasma facing components in nuclear fusion reactors. This would entail weathering extreme conditions, such as high thermal loads and particle bombardment. It is of vital importance to understand how tungsten mechanically responds to these conditions, and how it is impacted by the defects that form. The current communication considers how the mechan

Integration of Ferroelectric HfO2 onto a III-V Nanowire Platform

The discovery of ferroelectricity in CMOS-compatible oxides, such as doped hafnium oxide, has opened new possibilities for electronics by reviving the use of ferroelectric implementations on modern technology platforms. This thesis presents the ground-up integration of ferroelectric HfO2 on a thermally sensitive III-V nanowire platform leading to the successful implementation of ferroelectric tran

Assessment of exposure determinants and exposure levels by using stationary concentration measurements and a probabilistic near-field/far-field exposure model

Background: The Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation requires the establishment of Conditions of Use (CoU) for all exposure scenarios to ensure good communication of safe working practices. Setting CoU requires the risk assessment of all relevant Contributing Scenarios (CSs) in the exposure scenario. A new CS has to be created whenever an Operatio

Quantification of the inhaled deposited dose during sand and dust storms

Exposure to dust particles during a sand and dust storm (SDS) can be harmful for health. The first step to understand the health effects of such exposure is to quantify the amount of deposited dust particles in the respiratory tracts. In this book chapter, a brief summary is presented about: (1) the outbreak mechanisms dust particles and being airborne, (2) physical and chemical characteristics of

A Comparison of the Self-Perceived Organisational and Social Work Environment among Swedish Occupational Therapists in Different Job Sectors : An Observational Study

Sick leave due to mental health problems is increasing, and there is evidence that it is associated with the individual’s self-perceived organisational and social work environment. The aim of this study was to compare occupational therapists’ self-perceived organisational and social work environments in different job sectors. The goal is to identify the sectors with the most unfavourable work envi

Cohort profile: InfCareHIV, a prospective registry-based cohort study of people with diagnosed HIV in Sweden

PURPOSE: The Swedish InfCareHIV cohort was established in 2003 to ensure equal and effective care of people living with HIV (PLHIV) and enable long-term follow-up. InfCareHIV functions equally as a decision support system as a quality registry, ensuring up-to-date data reported in real time.PARTICIPANTS: InfCareHIV includes data on >99% of all people with diagnosed HIV in Sweden and up to now 13 0

Nowcasting COVID-19 Statistics Reported with Delay : A Case-Study of Sweden and the UK

The COVID-19 pandemic has demonstrated the importance of unbiased, real-time statistics of trends in disease events in order to achieve an effective response. Because of reporting delays, real-time statistics frequently underestimate the total number of infections, hospitalizations and deaths. When studied by event date, such delays also risk creating an illusion of a downward trend. Here, we desc

The influence of growth hormone on pediatric body composition : A systematic review

Background: Growth hormone (GH) affects metabolism and regulates growth in childhood. The most prominent feature of GH deficiency (GHD) in children is diminished height velocity that eventually leads to short stature. In adult-onset GHD, lean body mass (LBM) is reduced, and visceral fat mass (FM) increased. Beneficial effects of GH treatment on body composition in adults with GHD, including an inc

Near-real-time CO2 fluxes from CarbonTracker Europe for high-resolution atmospheric modeling

We present the CarbonTracker Europe High-Resolution (CTE-HR) system that estimates carbon dioxide (CO2) exchange over Europe at high resolution (0.1 × 0.2° ) and in near real time (about 2 months' latency). It includes a dynamic anthropogenic emission model, which uses easily available statistics on economic activity, energy use, and weather to generate anthropogenic emissions with dynamic time pr

COVID-19 and airborne transmission : science rejected, lives lost : can society do better?

This is an account that should be heard of an important struggle: the struggle of a large group of experts who came together at the beginning of the Covid-19 pandemic to warn the world about the risk of airborne transmission and the consequences of ignoring it. We alerted the World Health Organization (WHO) about the potential significance of the airborne transmission of SARS-CoV-2 and the urgent

Decision Support for Lake Restoration : A Case Study in Swedish Freshwater Bodies

A considerable number of lakes in Sweden have high phosphorus internal loading from the sediments which cause cyanobacterial blooms every summer. Due to potential risks with such blooms for human health, drinking water supply, and ecosystem services, measures need to be taken to control the phosphorus content. Measures to control the phosphorus input from the surrounding land has been in focus. Ho

Gauge Couplings Evolution from the Standard Model, through Pati–Salam Theory, into E8 Unification of Families and Forces

We explore the potential of ultimate unification of the Standard Model matter and gauge sectors into a single (Formula presented.) superfield in ten dimensions via an intermediate Pati–Salam gauge theory. Through a consistent realisation of a (Formula presented.) orbifolding procedure and renormalisation group evolution of gauge couplings, we establish several novel benchmark scenarios for New Phy

Conservative Management First Strategy in Aortic Vascular Graft and Endograft Infections

OBJECTIVE: The aim of this study was to describe and present the outcomes of a specific treatment protocol for aortic vascular graft and endograft infections (VGEIs) without explantation of the infected graft.METHODS: This was a retrospective, observational single centre cohort study carried out between 2012 and 2022 at a tertiary hospital. An aortic VGEI was defined according to the Management of