The role of hereditary factors in lung cancer is less well understood than in many other human neoplastic diseases. We used a nation-wide family dataset to search for evidence for a genetic predisposition in lung cancer. The Swedish Family-Cancer Database includes all Swedes born in 1932 and later (0- to 68-year-old offspring) with their parents, totaling over 10.2 million individuals. Cancer case

We used the nation-wide Swedish Family-Cancer Database to examine the risk for testicular cancer in offspring through parental and sibling probands. Among 0-68-year-old offspring, 4082 patients had testicular cancer in years 1961-2000, among whom 68 (1.67%) had an affected father/brother. Standardized incidence ratios (SIRs) for familial risk were four-fold when a father and nine-fold when a broth

Socio-economic gradients are known to exist in cancer but we want to focus on the university-educated population and specifically on physicians to find out whether their special educational background on cancer causation helps them to avoid cancers. The analysis was based on the latest update of the Swedish Family-Cancer Database, in which the educational level was obtained from the national censu

The importance of genetic factors in etiology of chronic lymphocytic leukemia (CLL) is suggested by family and population studies. However, the spectrum of malignancies sharing common genetic factors with CLL and the effects of sex and age on familial risk are unknown. We used the Swedish Family-Cancer Database to test for increased familial risks of CLL and other lymphoproliferative tumors. Cance

Background: Interatrial block (IAB) is an ECG indicator of atrial fibrosis related to atrial remodeling and thrombus formation thus leading to embolic stroke and increasing mortality. We aimed to assess weather IAB predicted all-cause mortality during 10 years after ischemic stroke. Methods: The study sample comprised 235 patients (median age 74 (interquartile range 25-75% 65-81) years, 95 female)

Background: Hip pain is prevalent in children with cerebral palsy (CP). Hip displacement is a known risk factor for hip pain. However, many children do not have displaced hips but still have hip pain and the aetiologies are poorly understood. The aims of this study were to investigate: 1. the prevalence of hip pain related to age, gender, gross motor function, degree of hip displacement and 2. the

OBJECTIVE: Although respiratory problems are common among patients with end-stage renal disease, respiration is not continuously monitored during dialysis. The purpose of the present study is to investigate the feasibility of monitoring respiration using the pressure sensors of the dialysis machine. APPROACH: Respiration induces variations in the blood pressure that propagates to the extracorporea

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extremely dense stroma, which has a fundamental role in tumor progression. Fibronectin (FN1) is the main constituent of the tumor stroma in pancreatic cancer. This study aimed to explore the association between FN1 and clinicopathological characteristics and disease survival. Methods: Formalin-fixed paraffin-embedded tissue

Background: There is a lack of validated tools to assess potential disease progression and hospitalisation decisions in patients presenting to the emergency department (ED) with a suspected infection. This study aimed to identify suitable blood biomarkers (MR-proADM, PCT, lactate and CRP) or clinical scores (SIRS, SOFA, qSOFA, NEWS and CRB-65) to fulfil this unmet clinical need. Methods: An observ

The production yield of the Λ(1520) baryon resonance is measured at midrapidity in Pb-Pb collisions at sNN = 2.76 TeV with the ALICE detector at the Large Hadron Collider (LHC). The measurement is performed in the Λ(1520)→pK- (and charge conjugate) hadronic decay channel as a function of the transverse momentum (pT) and collision centrality. The ratio of the pT-integrated production of Λ(1520) bar

Comprehensive results on the production of unidentified charged particles, π±, K±, KS0, K∗(892)0, p, p, φ(1020), Λ, Λ, Ξ-, Ξ+, Ω-, and Ω+ hadrons in proton-proton (pp) collisions at s=7 TeV at midrapidity (|y|

Suppression of boundary-driven Rayleigh streaming has recently been demonstrated for fluids of spatial inhomogeneity in density and compressibility owing to the competition between the boundary-layer-induced streaming stress and the inhomogeneity-induced acoustic body force. To understand the implications of this for acoustofluidic particle handling in the submicrometer regime, we here characteriz

In the Mediterranean area, the 4.2 ka BP event is recorded with contrasting expressions between regions. In the southern Alps, the high-altitude Lake Petit (Mercantour Massif, France; 2200 m a.s.l.) offers pollen and diatom-rich sediments covering the last 4800 years. A multi-proxy analysis recently revealed a detrital pulse around 4200 cal BP due to increasing erosion in the lake catchment. The

Förra sommaren gästades SLF den 13–17 juni av den brittiska motsvarigheten BLS genom en inbjudan av Lars Borg, som ibland gästat deras exkursioner i England. Vi var förlagda till Allégården i Kastlösa på Öland varifrån vi gjorde utflykter till olikadelar av södra och mellersta Öland. En halvdag ägnades också åt en typiskt sur tallskog på fastlandet i närheten av Kalmar. Här berättar Ulf om den hisBrigantiaea crystallina Arup is described as new to science from South Korea and Japan. It is similar to B. purpurata but has a pale to pale brownish orange hypothecium, an excipulum penetrated by brownish orange anthraquinonecrystals as well as colourless crystals that appear white in polarised light, the spores are smaller and the thallus lacks zeorine. The new species is illustrated and compare

This dissertation contributes to the field of Islamic Studies by analyzing how the production of Islam can be seen as the outcome of interactions between actors who define themselves as Muslims as well as those who do not. The argument of this dissertation is that Muslims as well as non-Muslims have used Islamic themes in their artistic productions throughout the history of African American music

Lake Titicaca is a crucial water resource in the central part of the Andean mountain range, and it is one of the lakes most affected by climate warming. Since surface evaporation explains most of the lake's water losses, reliable estimates are paramount to the prediction of global warming impacts on Lake Titicaca and to the region's water resource planning and adaptation to climate change. Evapora

We report on growth of InP-InAs core-shell nanowires and demonstration of the formation of single quantum structures, which show the Coulomb blockade effect, over entire lengths of the nanowires. The core-shell nanowires are grown by a selective area growth technique via metal-organic vapor phase epitaxy. The as-grown core-shell nanowires are found to be of wurtzite crystals. The InP cores have a

Inhibition of amyloid β peptide (Aβ) aggregation is an important goal due to the connection of this process with Alzheimer's disease. Traditionally, inhibitors were developed with an aim to retard the overall macroscopic aggregation. However, recent advances imply that approaches based on mechanistic insights may be more powerful. In such approaches, the microscopic steps underlying the aggregatio

This article is an empirically grounded conceptual investigation of the failures of mediatized activism in 2011 in Azerbaijan and Turkey. By analyzing two specific cases, namely the complete dispersion of corporate social media based opposition in Azerbaijan, and arrests of Anonymous led hacktivists in Turkey, the article aims to contribute to the discussion on the future of mediatized activism in