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The development of human breast cancer is characterized by a variety of genetic alterations, and cytogenetic analyses have documented the consistent involvement of both arms of chromosome I. In the present study, molecular markers detecting restriction fragment length polymorphisms were used in pairwise screening of normal and tumor DNA to determine the frequency of allelic imbalance in breast tum
Using a self-report questionnaire, the Hospital Anxiety and Depression (HAD) scale, feelings of anxiety and depression were assessed in 133 breast cancer patients referred for adjuvant radiotherapy following surgical treatment. Eighteen patients (14% had scores indicating morbid anxiety. Significant depression was recorded for only 2 patients (1.5% Severe anxiety was recorded for 10 out of 54 mast
Southern travelling habits were recorded for 127 melanoma patients from southern parts of Sweden (the 56th latitude), 55 thyroid cancer patients, 100 non-Hodgkin's patients and 794 healthy controls from the same region. Melanoma patients were found to travel significantly more often south of the 45th latitude, as compared with patients with non-Hodgkin's lymphoma or thyroid carcinoma (RR = 2.2 for
The significance of the retinoblastoma gene (RB) in the development of human breast cancer remains unclear. In the present study, loss of heterozygosity (LOH) in RB was found in 26% of 90 informative primary breast tumors and was correlated to DNA nondiploidy, a high S-phase fraction, and LOH at chromosome 17pl33. However, allele loss was not associated with loss of RB protein (pRB) expression. Lo
Denna artikel undersöker vilken betydelse och potential som begreppet musikalitet kan ha för skådespelares lärprocesser. Studien riktar sig främst till lärare och forskare vid landets högre konstnärliga utbildningar. Betraktad som professionsforskning och som exempel på språkliga metaforers potential i konceptualiserings- och lärandeprocesser bör den emellertid kunna vara av intresse även för andr
Fundamental bounds on antenna gain are found via convex optimization of the current density in a prescribed region. Various constraints are considered, including self-resonance and only partial control of the current distribution. Derived formulas are valid for arbitrarily shaped radiators of a given conductivity. All the optimization tasks are reduced to eigenvalue problems, which are solved effi
Meniscal extrusion (ME) in the knee joint is defined as when the peripheral border of the meniscus is substantially located outside the joint margin. Prior studies have reported that ME is associated with meniscal tears, meniscal degeneration, and the presence of knee osteoarthritis (OA). Medial ME of the body of 3 mm or more, as seen on knee Magnetic Resonance Imaging (MRI) has a wide acceptance
This paper presents the results from two studies on anaphoric reference to quantifying expressions (QEs) in Swedish, contributing to the current cross-linguistic discussion on this issue. For English it has been shown that the polarity of the QE (positive vs negative) determines the anaphoric set reference (to the referens set, REFSET, or to the complement set, COMPSET), while for Spanish it has b
This article examines challenges to the classical paradigm of education in Sweden that followed in the wake of state-initiated attempts at school reform in the first decades of the nineteenth century. When the internal disputes of the so-called ‘Genius Committee’ resulted in a failure to overcome the increasing divide between reformers, a prolific opportunity to argue the value of practical subjec
De litterära karaktärerna är väsentliga för om läsarna ska engagera sig i en text och uppleva den som intressant och meningsfull, antingen man skapar egna karaktärer eller skriver fanfiction och diktar vidare på karaktärer som andra författare byggt upp. Gestaltningen är central och många unga ägnar sig åt att dikta vidare på kända verk, något som väcker frågan om vem som ”äger” de fiktiva karaktä
This Letter presents a search for heavy charged long-lived particles produced in proton–proton collisions at s=13TeV at the LHC using a data sample corresponding to an integrated luminosity of 36.1fb−1 collected by the ATLAS experiment in 2015 and 2016. These particles are expected to travel with a velocity significantly below the speed of light, and therefore have a specific ionisation higher tha
Transverse momentum (pT) spectra of charged particles at mid-pseudorapidity in Xe–Xe collisions at sNN=5.44TeV measured with the ALICE apparatus at the Large Hadron Collider are reported. The kinematic range 0.15
The measurement of dielectron production is presented as a function of invariant mass and transverse momentum (pT) at midrapidity (|ye|<0.8) in proton–proton (pp) collisions at a centre-of-mass energy of s=13 TeV. The contributions from light-hadron decays are calculated from their measured cross sections in pp collisions at s=7 TeV or 13 TeV. The remaining continuum stems from correlated semilept
The β-decay rates of 60Ca have been studied within a microscopic model, which is based on the Skyrme interaction T45 to construct single-particle and phonon spaces. We observe a redistribution of the Gamow-Teller strength due to the phonon-phonon coupling, considered in the model. For 60Sc, the spin-parity of the ground state is found to be 1+. We predict that the half-life of 60Ca is 0.3 ms, whil
