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Popular Abstract in Swedish Hjärt- kärlsjukdomar är den vanligaste dödsorsaken i Sverige. Den bakomliggande orsaken till de allra flesta fall av hjärt- kärlsjukdom är vad som i vardagligt tal kallas åderförkalkning. Den medicinska termen för åderförkalkning är ateroskleros. Ateroskleros är en inflammatorisk sjukdom i artärerna som orsakas av att LDL-partiklar, det så kallade onda kolesterolet, ansThe immune system is a promising target for novel therapies that are aiming at reducing cardiovascular diseases. Autoimmune responses against modified low density lipoprotein (LDL) are believed to promote development of atherosclerosis. Proinflammatory immune responses can be counterbalanced by immunosuppressive regulatory T cells (Tregs). Immunizations of hypercholesterolemic mice with oxidized L

Trait anxiety, working memory capacity, and the effectiveness of memory suppression. Scandinavian Journal of Psychology. We aimed at replicating the finding that humans are able to suppress unwanted memories, and tested whether this ability varies with individual differences in working memory capacity, trait anxiety and defensiveness. In a think/no-think experiment, participants either recalled or

We report the synthesis of thermosensitive raspberry-like hybrid microgels. They consist of a poly(N-isopropylacrylamide) core decorated with in situ formed silica particles. A linking silane agent was copolymerized to help the anchoring of silica particles formed by a controlled silica precursor addition onto the outer shell. The thermosensitive behaviour is tuneable by adjusting the size of the

Molecularly imprinted polymers (MIPs) targeting quercetin were prepared from 4-vinylpyridine and ethylene dimethacrylate (EDMA) under various solvent systems with the aim to form MIPs with high recognition for the quercetin molecule in aqueous systems at high temperature. A MIP prepared from the three-component solvent mixture of THF/H2O/MeOH showed potential in its application for the determinati

LACM 128319, which was collected in western Kansas, U. S. A., and is assignable to Platecarpus tympaniticus (Mosasauridae, Plioplatecarpinae), represents arguably one of the most exquisite mosasaur specimens known to date. Measuring 5.67 m from the tip of the snout to the end of the tail, it comprises an exceptionally well-articulated skeleton, accompanied by soft-tissue remains, such as skin impr

De vanligtvis beaktade fossilfria alternativen till dagens olje- och fossilgasbaserade drivmedel i transportsektorn är förnybar el, vätgas och biodrivmedel. De begränsningar, osäkerheter och problem som finns med batterier, vätgas och biodrivmedel gör det intressant att beakta möjligheterna att från el producera kolhaltiga drivmedel – flytande och gasformiga kolväten. Dessa så kallade elektrobräns

Pathological complete response (pCR) following chemotherapy is strongly associated with both breast cancer subtype and long-term survival. Within a phase III neoadjuvant chemotherapy trial, we sought to determine whether the prognostic implications of pCR, TP53 status and treatment arm (taxane versus non-taxane) differed between intrinsic subtypes. Patients were randomized to receive either six cy

Background: The evidence that individual dietary and lifestyle factors influence a person's weight and waist circumference is well established; however their combined impact is less well documented. Therefore, we investigated the combined effect of physical activity, nutrition and smoking status on prospective gain in body weight and waist circumference. Methods: We used data of the prospective EP

Digital controllers are traditionally implemented using periodic sampling, computation, and actuation events. As more control systems are implemented to share limited network and CPU bandwidth with other tasks, it is becoming increasingly attractive to use some form of event-based control instead, where precious events are used only when needed. Forms of event-based control have been used in prac

Fetal cell replacement therapy or in utero hematopoietic cell transplantation (IUHCT) is proposed as a non-myeloablative alternative to bone marrow transplantation (BMT) for a number of inborn immunologic, hematologic and metabolic disorders. IUHCT represents the method through which variable amounts of natural or genetically modified hematopoietic cells can be transferred to the fetal recipient i

Background and aims: To estimate short- and long-term costs of inpatient hospitalization in Sweden for major diabetes mellitus-related events. Materials and methods: Costs were estimated using administrative hospital data from the Swedish National Board of Health and Welfare, which is linked to the Swedish National Diabetes Register. Data were available for 179 749 patients with diabetes in Sweden

Provocation is an integral part of Socrates’ philosophical method. Does provocation have a similar methodological function in art? My tentative answer is no. In the Socratic method, provocation is used both on an individual level to force a person to think better (preferably in ethical matters) and on a general level in order to keep a society awake. A society should never rest but “be stirred int

Two separate apps that address the increasingly important issue of accessible housing for senior citizens have been developed in different project settings. One of the apps was developed to facilitate the process for professional raters to assess housing accessibility in the context of individual housing adaptations. The other app was developed for senior citizens to raise their awareness of possi