The tyrosine kinase encoding genes ABL1 and FGFR1 are involved in fusion genes underlying the myeloproliferative neoplasms chronic myeloid leukemia (CML) and the 8p11-myeloproliferative syndrome (EMS). CML and EMS are both myeloproliferative disorders with an initiating, relatively indolent, chronic phase that after some time progresses into acute myeloid or lymphoid leukemia. The mechanisms under

Seismic reflection data contain surface waves that can be processed and interpreted to supply shear-wave velocity models along seismic reflection lines. The coverage of seismic reflection data allows the use of automated multifold processing to extract high-quality dispersion curves and experimental uncertainties in amoving spatial window. The dispersion curves are then inverted using a determinis

As the most figurative asset of membership in a majority or minority and the most symbolic aspect of national authority, language is a major site of struggle for majority power and minority resistance. For the purposes of this study, which focuses on the question of Kurdish linguistic rights in Turkey, the sites of struggle for majority power and minority resistance are as follows: the documents o

Charged particles and photons have been measured in central Pb + Pb collisions at 158 A GeV in a common (eta-phi)-phase space region in the WA98 experiment at the CERN SPS. The measured distributions have been analyzed to quantify the frequency with which phase space regions of varying sizes have either small or large neutral pion fraction. The measured results are compared with VENUS model simula

Abstract in UndeterminedWe analyze empirically export-price strategies across export destinations using detailed firm-product data. Most recent studies using disaggregated data to investigate why firms charge different prices for the same product on different markets focus on the cost component of prices and neglect the markup component. In this paper, we concentrate on the markup component and ex

Popular Abstract in Swedish Cancer är ett samlingsnamn för en grupp av sjukdomar som karakteriseras av att cellerna delar sig okontrollerat, till skillnad mot kroppens friska celler. Det leder till att en tumör kan bildas och cellerna kan därifrån sprida sig till andra delar av kroppen och ge upphov till dottertumörer, även kallade metastaser. I Sverige uppskattar man att cirka var tredje person kSmall cell lung carcinoma (SCLC) is a very aggressive solid tumor and is often widely metastasized by the time of diagnosis. Despite good response to the initial chemotherapy, SCLC cells often develop multidrug resistance to conventionally used chemotherapeutic drugs, which cause almost all SCLC tumors to relapse. The 5-year survival rate for patients with limited disease is around 20% while it is

InGaAs nanowires grown by Metalorganic Vapor Phase Epitaxy (MOVPE) are promising candidates in future device technologies. The control of the chemical composition of InGaAs nanowires is not trivial due to the In atom diffusion from the substrate, which causes significant variations in the chemical composition along the nanowire. In this work, we report on the growth of InGaAs nanowires on (111)B I

We report on the measurement of the inclusive Upsilon(1S) production in Pb-Pb collisions at root s(NN) = 2.76 TeV carried out at forward rapidity (2.5 < y < 4) and down to zero transverse momentum using its mu(+)mu(-) decay channel with the ALICE detector at the Large Hadron Collider. Astrong suppression of the inclusive Upsilon(1S) yield is observed with respect to pp collisions scaled by the num

While the effect of disturbance on overall abundance and community composition of arbuscular mycorrhizal (AM) fungi has been researched in agricultural fields, less is known about the impact in semi-natural grasslands. We sampled two AM plant species, Festuca brevipila and Plantago lanceolata, from an ongoing grassland restoration experiment that contained replicated plowed and control plots. The

The impact of pH coupled to process design for the conversion of the energy crop Arundo donax to ethanol was assessed in the present study under industrially relevant solids loadings. Two main process strategies were investigated, i.e. the traditional simultaneous saccharification and co-fermentation (SSCF) and a HYBRID design, where a long high temperature enzymatic hydrolysis step was carried ou

4-Substituted bicyclo[2.2.2]octane-2,6-diones have been synthesized and tested as substrates in the enantioselective reduction with baker's yeast to give the corresponding hydroxy ketones. It was found that the derivative bearing a TIPSO group at the 4-position was not reduced at all while that with a TBDMSO group gave 87% yield and 46% ee. Other 4-oxy functionalized derivatives were reduced with

Den svenska yrkesutbildningen gick igenom ett dramatiskt systemskifte under mellan 1940 och 1975. från att i huvudsak ha varit praktisk och arbetsplatsförlagd till att bli skolförlagd med begränsad kontakt med arbetslivet. Det var en så stor förändring att den måste betecknas som ett systemskifte inom yrkesutbildningen. I ett internationellt perspektiv är ett sådant skifte ovanligt och skutresulta