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Reduced lung function is associated with cardiovascular mortality, but the relationships with atherosclerosis are unclear. The population-based Swedish CArdioPulmonary BioImage study measured lung function, emphysema, coronary CT angiography, coronary calcium, carotid plaques and ankle-brachial index in 29,593 men and women aged 50–64 years. The results were confirmed using 2-sample Mendelian rand
Feathers comprise a series of evolutionary innovations but also harbour colour, a key biological trait known to co-vary with life history or complex traits. Those relationships are particularly true in melanin-based pigmentation species due to known pleiotropic effects of the melanocortin pathway – originating from melanin-associated phenotypes. Here, we explore the molecular basis of melanin colo
Rendered imagery is presented to us daily. Special effects in movies, video games, scientific visualizations, and marketing catalogs all often rely on images generated through computer graphics. However, with all the possibilities that rendering offers come also a plethora of challenges. This thesis proposes novel ways of evaluating the visual errors caused when some of those challenges are not co
This article aims at illuminating the role of Swedish and Norwegian municipalities as legal actors in multi-level governance. The research questionis threefold: What is the role of Swedish and Norwegian municipalities as legal actors in relation to the European level? How do these roles affect local autonomy at the national level? What is the impact of the different affiliations at the European le
Collaboration between academia and practice is crucial for addressing complex societal challenges and generating new knowledge. However, bridging the perceived gap between these two domains has proven challenging due to differences in language, expectations, and time horizons. In this article, we question the usefulness of framing these differences as a gap and explores alternative approaches to f
Delirium is a serious and common condition in the intensive care unit (ICU), which affects 30-50 % of the patients and is associated with increased mortality and morbidity in the context of long-term outcomes. No evidence-based treatment for delirium exists, and currently, delirium is mainly treated pharmacologically with haloperidol, a typical antipsychotic agent. The “Agents Intervening against
It is vital to consider acoustic scattering when using geometrical acoustic simulation techniques, such as ray tracing. However, there are few methods for modelling scattering, and most rely on strong assumptions of uniformity on the distribution of scattered energy. In this paper, a model for directional scattering in ray tracers is presented. The model is based on an idealized model of a 1D scat
Room acoustic simulations are an important tool, both for design of spaces with satisfactory acoustics and for use in virtual reality experiences. Auralization of acoustic simulations are becoming more and more important in the context of Virtual and Augmented reality (VR and AR respectively), as the technology is used more and more in healthcare, culture and research. In this work, ray tracing si
Traditionally, psychophysical data is modelled by fitting individual curves to each participant’s data and then by statistical analysis of the extracted parameters. A now viable alternative to this traditional two-stage approach is Bayesian hierarchical modelling (BHM). BHM allows for modelling all of the data and all of the parameters in one-step rather than two. Here, BHM is used to analyse the
The emergence of complementary and community currencies (CCCs) at a global and local scale manifests the normative innovation that characterizes these initiatives. Based on three case studies of CCCs in the Basque Country (the Ekhi, the Eusko and the Txantxi) the present paper explores the normative order of the CCCs and their processes of institutionalization through tactics of legal convergence.
Although we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex. This article lays out major gaps in our knowledge of interrelationships between brain metabolism and brain function, including biochemical, cellular, and subcellular aspects of functional metabolism and its imaging in adult brain, as well
I projektet studeras det digitala verktyget Flow och dess inverkan på personalens arbetsmiljö samt på kostnadseffektiviteten i svensk primärvårdskontext. Flow ger patienten möjlighet till digital kontakt och kommunikation med vårdcentralen samt möjlighet till digital kommunikation mellan olika personalgrupper inom vårdcentralen. Implementeringen av Flow har studerats på tre vårdcentraler: A, B oc
In this contribution, we propose a model of Quaternary seismicity in the Outer Western Carpathians. The model presents results of analysis of fractured clasts performed in 268 exposures of Quaternary fluvial gravels within the ca. 5,000 km2 large segment of the Outer Western Carpathians comprising: Outer Carpathian nappes, the innermost part of the Carpathian Foredeep, and two intramontane basins
INTRODUCTION: The pace of innovation has accelerated in virtually every area of tau research in just the past few years. METHODS: In February 2022, leading international tau experts convened to share selected highlights of this work during Tau 2022, the second international tau conference co-organized and co-sponsored by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation
