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Molecular mechanisms preventing self-renewing brain stem cells from oncogenic transformation are poorly defined. We show that the expression levels of SOX5, SOX6, and SOX21 (SOX5/6/21) transcription factors increase in stem cells of the subventricular zone (SVZ) upon oncogenic stress, whereas their expression in human glioma decreases during malignant progression. Elevated levels of SOX5/6/21 prom
The aim was to assess the ability of microcosms (laboratory-scale shallow ponds) as a post polishing stage for the remediation of artificial textile wastewater comprising two commercial dyes (basic red 46 (BR46) and reactive blue 198 (RB198)) as a mixture. The objectives were to evaluate the impact of Lemna minor L. (common duckweed) on the water quality outflows; the elimination of dye mixtures,
During recent years, numerous studies have shown the ability of dietary fiber toprotect the colon from disease and to improve intestinal health. Beneficial healtheffects, such as the lowering of blood cholesterol levels and a reduction in the risk of coronary heart disease, are often directly related to cereal β-glucan, one of the major components of dietary fiber found in oat and barley. No defin
Patients with Alzheimer's disease can present with different clinical phenotypes. Individuals with late-onset Alzheimer's disease (465 years) typically present with medial temporal lobe neurodegeneration and predominantly amnestic symptomatology, while patients with early-onset Alzheimer's disease (565 years) exhibit greater neocortical involvement associated with a clinical presentation including
While ecosystem-based planning approaches are increasingly promoted through international and national policies, municipalities are still struggling with translating them into practice. Against this background, this paper aims to increase the knowledge of current advances and possible ways to support the implementation of the ecosystem services (ES) approach at the municipal level. More specifical
Ultrafast processes in matter, such as the electron emission following light absorption, can now be studied using ultrashort light pulses of attosecond duration (10−18 s) in the extreme ultraviolet spectral range. The lack of spectral resolution due to the use of short light pulses has raised issues in the interpretation of the experimental results and the comparison with theoretical calculations.
Background: Severity of the primary unilateral cleft lip/nose deformity (UCL/N) is postulated to play a key role in postoperative complications, aesthetic result, and need for secondary surgery. There is no validated and widely accepted classification scheme of initial cleft severity. The purpose of this study was to validate the Unilateral Cleft Lip Cleft Severity Index as a reliable tool for eva
Background: A standardized evaluation tool is needed for the assessment of surgical outcomes in cleft lip surgery. Current scales for evaluating unilateral cleft lip/nose (UCL/N) aesthetic outcomes are limited in their reliability, ease of use, and application. The Unilateral Cleft Lip Surgical Outcomes Evaluation (UCL SOE) scale measures symmetry of 4 components and sums these for a total score.
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. Here we report the results of a genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of
Purpose – The purpose of this paper is to analyze the role of innovation on the export behavior of firms. Design/methodology/approach – Using two waves of Swedish Community Innovation Survey merged with register data on firm-level, the authors estimate the influence of the innovation output and innovation input of firms on their export propensity and intensity. Findings – The authors find that the
Sedan mitten på 1900 talet har halvledarmaterial revolutionerat hur vi ser på världen genom uppfinningar som det har gett upphov till, såsom datorer, solceller, och lysdioder. Det är möjligheten att kunna styra halvledarens förmåga att leda ström—mellan att vara nästan metallisk till att vara isolerande—som gör den användbar för tillämpningar inom elektronik. Under de senaste decennierna har elektThis dissertation focus on the atomic-scale characterization of the surface properties and electronic structure of III–V semiconductor nanowires (NWs). Since the early 2000s, the fabrication and characterization of III–V NWs has been a very significant topic within material science due to their potential for applications in lighting, energy harvesting, and electronics. A prominent feature of the N
Relative clauses are considered strong islands for extraction across languages. Swedish comprises a well-known exception, allegedly allowing extraction from relative clauses (RCE), raising the possibility that island constraints may be subject to "deep variation" between languages. One alternative is that such exceptions are only illusory and represent "surface variation" attributable to independe
The current study compares controlled acceptability judgments for Swedish relative clause extractions to extractions from that-clauses and extractions from non-restrictive relative clauses. It also compares each structure in both extracted and non-extracted form. The reported possibility of relative clause extraction in Swedish (and the other Mainland Scandinavian languages) has long presented a c
This paper presents two novel findings: I show (i) that there is a strong connection between ϕ-feature agreement and scope freezing in Swedish, and (ii) that Swedish tough-constructions (TCs) involve movement of the embedded object into the matrix subject position. Scope freezing is shown to take place in adjectival TCs, morphological passives and adjectival raising structures in Swedish, but not
