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Novel tenascin variants with a distinctive pattern of expression in the avian embryo

Previous studies have shown that several forms of the glycoprotein tenascin are present in the embryonic extracellular matrix. These forms are the result of alternative splicing, which generates tenascin variants with different numbers of fibronectin type III repeats. We have used degenerate primers and PCR to isolate a novel tenascin exon from an avian genomic library. Genomic clones contained a

Energy and virtuality scale dependence in quark and gluon jets

We discuss some important issues concerning multiplicities in quark and gluon jets in e+e- annihilation. In QCD the properties of a jet in general depend on two scales, the energy and virtuality of the jet. Frequently theoretical predictions apply to a situation where these scales coincide, while for experimental data they are often different. Thus an analysis to extract e.g. the asymptotic multip

Tenascin-C expression by fibroblasts is elevated in stressed collagen gels

Chick embryo fibroblasts cultured on a collagen matrix exert tractional forces leading to the contraction of unrestrained, floating collagen gels and to the development of tension in attached, restrained gels. On a restrained, attached collagen gel the fibroblasts synthesize large quantities of tenascin-C, whereas in a floating, contracting gel tenascin-C synthesis is decreased. This regulation of

Nerve-dependent and -independent tenascin expression in the developing chick limb bud

The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Tenascin accumulates along developing peripheral nerves as they leave the spinal cord and enter the limb mesenchyme (Wehrle and Chiquet, Development 110, 401-415, 1990). Here we found that most but not all tenascin deposited along growing nerves is of glial origin. By in situ hybridization with

Epithelial synthesis of tenascin at tips of growing bronchi and graded accumulation in basement membrane and mesenchyme

The extracellular matrix protein, tenascin, has been proposed as mediator in epithelial-mesenchymal interactions because of its characteristic distribution during embryogenesis. Here we compared the accumulation of tenascin and laminin in the early chicken lung bud. Laminin is deposited in the basement membrane, starting at the tips and increasing along the shafts of growing primary and secondary

Molecular characterization of spalt, a homeotic gene required for head and tail development in the Drosophila embryo

The isolation, identification and structure of the spalt gene is described. This novel homeotic gene of Drosophila is required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo. It encodes a small mRNA of 0.8 kb which is under the control of over 15 kb of upstream sequences as indicated by the phenotype of transformed embryos. The putative spalt pro

Magnetism and magneto-structural effects in transition-metal sulphides

Recent density-functional studies of the structural and electronic properties of a wide range of transition-metal sulphides (Raybaud P, Kresse G, Hafner J and Toulhoat H 1997 J. Phys.: Condens. Matter 9 11085, 11 107) are extended to consider the effect of magnetic ordering in sulphides formed by 3d transition metals. We find that CrS is well described as an itinerant antiferromagnet and that the

IMS at the CoNLL 2017 UD Shared Task: CRFs and Perceptrons Meet Neural Networks

This paper presents the IMS contribution to the CoNLL 2017 Shared Task. In the preprocessing step we employed a CRF POS/morphological tagger and a neural tagger predicting supertags. On some languages, we also applied word segmentation with the CRF tagger and sentence segmentation with a perceptron-based parser. For parsing we took an ensemble approach by blending multiple instances of three parse

Cloning of the extra sex combs gene of Drosophila and its identification by P-element-mediated gene transfer

A large region containing the extra sex combs (esc) gene of Drosophila has been cloned by microdissection from polytene chromosomes and chromosomal walking. Within this DNA, the segment comprising the esc gene has been narrowed down in several steps. First, a deletion of the esc gene, Df(2L)esc, defined a region of 380 kb. Then, a duplication carrying the esc gene, Dp(2;2)GYL, and a deletion not e

Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells

Preeclampsia (PE) has been associated with placental dysfunction, resulting in fetal hypoxia, accelerated erythropoiesis, and increased erythroblast count in the umbilical cord blood (UCB). Although the detailed effects remain unknown, placental dysfunction can also cause inflammation, nutritional, and oxidative stress in the fetus that can affect erythropoiesis. Here, we compared the expression o