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The functional decline of hematopoietic stem cells (HSCs) with age is a well-documented phenomenon, associated with various health complications, including anemia, impaired immune responses, and chronic inflammation. This dysfunction can contribute to the onset of hematological disorders such as myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML

Enhancers are central regulators of cell-type-specific gene expression, yet direct functional mapping of active enhancer-promoter interactions in single cells remains technically challenging. DNA adenine methyltransferase (Dam)-based chromatin recording offers a strategy to mark genomic regions proximal to proteins associated with active transcription sites in vivo, including enhancer regions, and

The introduction of the Environmental Transmission Electron Microscope (ETEM) has revolutionized scientific studies by allowing in-situ studies of nano and angstrom scale samples in varying environments. In combination with the introduction of the Microelectromechanical Systems (MEMS) chip the ETEM has become a powerful tool for high resolution imaging of material interaction. However, the MEMS ch

With climate change causing more intense rainfall events and prolonged droughts, freshwa-ter resources are increasingly under pressure worldwide, including in regions such as Sweden where water scarcity was previously unexpected. While water conservation can reduce de-mand to some extent, long-term water security requires alternative and resilient water sources. Wastewater represents a reliable so

The city is a place where different activities take place side by side. The private next to the public, the sacred next to the everyday. For this, a rich variety of spaces is required - fronts and backs, insides and outsides, large and small, common and private. A spatial ecology of rooms, streets, passageways, and courtyards, relating and dependent on each other. Both general and specific. What m

Accurate thermometry is essential for experiments in cryogenic environments, particularly those using dilution refrigeration to reach milli-Kelvin temperatures. In this thesis, the calibration range of a Cernox CX1050 sensor was extended below its nominal lower limit of 1.4 K. In addition, the response of RuOx sensors at different positions within the dilution refrigerator was examined to assess t

Indoor positioning is a challenging problem due to complex environments, signal attenuation, and multi-path effects. A promising approach to this problem is channel charting on wireless networks, where high-dimensional channel state information (CSI) is mapped into a low-dimensional latent space, which preserves spatial relationships in a self-supervised manner. Channel charting can be deep learni

This thesis investigates the possibility of shortening setup times for the hardware testing rigs at BorgWarner’s Landskrona location. All the test rigs in question use the same measurement and control software, NI VeriStand. NI VeriStand is a data acquisition and control software created by National Instruments. This software needs a certain file, a system definition file,to coordinate the communi

The Machine and Assembly Hall in Varvsstaden (Malmö, Sweden) is a heritage industrial building currently being refurbished into office space. As part of the renovation, the historic cast-iron framed windows will be complemented by an inner insulating window installed approximately 500 mm inside the existing line, creating an air cavity and altering the mechanical loading conditions of the original

The decrease in wetland area worldwide has caused serious declines to populations of aquatic organisms. Stormwater ponds are constructed to clean runoff water and act as buffers for floods but are also part of the aquatic landscape. In this thesis I have studied how they can contribute to biodiversity by examining which environmental factors influence benthic macroinvertebrate richness, abundance

Detta examensarbete utvärderar effekterna av vägbelysning på cykling på supercykelvägen mellan Lund och Dalby, med särskilt fokus på en landsbygdsmiljö. Syftet är att undersöka hur belysning påverkar cyklisters framkomlighet, upplevd trafiksäkerhet och trygghet. Studien tillämpar en kombinerad metodansats som kombinerar clock-change-metoden, videobaserade hastighetsmätningar och semistrukturerade This thesis evaluates the effects of road lighting on cycling on the super cycleway between Lund and Dalby, with a focus on a rural environment. The aim is to assess how lighting influences cyclists’ mobility, perceived traffic safety, and perceived safety. The study applies a mixed-method approach, combining the clock-change method to analyze cycling volumes, video-based speed measurements, and s

This thesis examines whether more generous unemployment insurance is associated with greater household portfolio risk-taking in Europe by reducing background income risk. Using a largely balanced panel of European countries, the analysis measures household risk-taking as the share of household financial assets held in equity and investment fund shares. Unemployment insurance generosity is proxied

The democratic implications of environmental policy instruments, is a complex matter of theoretical and normative questions, this paper aims to explore. The purpose is to analyse how different governance tools like regulatory and market-based instruments, relate to central democratic values in environmental policymaking. Rather than treating policy instruments as neutral technical tools, the study

Uppsatsens ämne är hur ”ändrade förhållanden” i kommersiella avtal behandlas inom avtalsrätten. Med ändrade förhållanden i avtalsrätten syftas det i uppsatsen till den situation då en plötsligt inträffad händelse, oväntad och ej orsakad av parterna drabbar avtalet. Om händelser i en pågående turbulent omvärld kan anses utgöra ändrade förhållanden är ett högaktuellt ämne som har väckt frågor om hurThe topic of this essay is how “changed circumstances” in commercial agreements are treated in contract law. In this essay, changed circumstances in contract law refers to a situation where a sudden incident, that is unexpected and not caused by the parties, affects the contract. Whether or not ongoing events in a turbulent world can be considered to constitute so-called changed circumstances is a

Blue carbon, defined as carbon fixed by marine plants, has gained attention as a climate change mitigation strategy. Coastal ecosystems play an important role in blue carbon storage due to their high carbon burial rates. Although the dynamics of the partial pressure of CO2 in seawater (pCO2) are closely related to blue carbon processes, studies investigating pCO2 variability in coastal areas remai

Understanding the physical properties and flow behaviour of foods is essential for designing reliable processing equipment. In this thesis, the rheological properties and flow behaviour of Pasta Filata cheese are investigated to improve the understanding of the flow-distribution inside a Tetra Pak Cheese Extruder. Uneven flow-rates have been observed during production, which lead to inconsistent d