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Broad-band spectral electrical impedance tomography (sEIT) measurements with a centralized multiplexer and coaxial cables

Spectral electrical impedance tomography (sEIT) has attracted increasing interest in hydrogeology, biogeosciences, agriculture and environmental studies. However, broad-band sEIT measurements, particularly at frequencies above 50 Hz, have long been challenging due to electromagnetic (EM) coupling effects. Recent advances in instrumentation, data correction and filtering have improved sEIT measurem

Autonomy within limits: Post-growth and social imaginaries of work, education and democracy

Autonomy is central to thinking about democracy and human needs, but the question of how autonomy relates to growth is ambivalent. Is growth necessary to achieve a basic level of autonomy, or is autonomy, in fact, a pre-requisite for post-growth? In this study, we examine this question by focusing on how critical autonomy relates to growth within the domains of democracy, education, and work. Crit

Achieving collaboration between local and regional governments aiming to stagger school starting hours

The peak-hour travel demand is the most important operational cost driver for public transport in Sweden. Implementing staggered school starting hours as a measure to spread out the travel demand has proven to be challenging. This study focuses on overcoming barriers to collaboration between public transport authorities, municipalities, and schools concerning school transport planning and school o

CSF markers of neuroinflammation, synaptic dysfunction and [18F]DOPA-PET in Parkinson's disease

Introduction: Neuromelanin containing cell loss, neuroinflammation and synaptic dysfunction are believed to contribute to Parkinson's disease (PD) pathogenesis. [18F]DOPA PET reflects dopamine storage capacity in the putamen, while midbrain off-target retention of [18F]RO948 is hypothesized to reflect neuromelanin. Objectives: To investigate associations between disease duration, cerebrospinal flu

How long is long enough for traffic conflict observation : An investigation using extreme value theory approaches

Determining the appropriate duration for traffic conflict observation remains a critical yet unresolved challenge in road safety analysis. Existing approaches lack a quantitative approach to determine adequate sample sizes for general conflict-based applications. This study addresses this gap by proposing an extreme value theory based framework to determine appropriate observation durations, based

Spatiotemporal distribution variation of extreme temperatures under elevation-dependent warming and its response characteristics to regional warming in Qinling-Daba Mountains, China

This study analyzed daily temperature data from 114 meteorological stations in the Qinling-Daba Mountains from 1980 to 2017, focusing on core zones (CE I ≥ 2274 m, CE II 1321–2274 m) and peripheral zones (PE I 668–1321 m, PE II < 668 m). Using 15 extreme temperature indices computed with RClimDex, we assessed the spatiotemporal patterns, trends, and response to climate warming of extreme temperatu

Barometry of Clinopyroxene in Xenoliths from the Anaga Region in Tenerife – Constraints on the Magmatic Plumbing System

Cumulate xenoliths from beach boulders in Anaga, Tenerife were analyzed through optical microscopy, scanning electron microscopy (SEM), both EDS and EBSD, and barometric modelling to study the magmatic evolution and volcanic plumbing system of the Anaga massif. Petrographic results indicate crystallization from hydrous basaltic magmas at equilibrium. This was further supported with chemical analy

Evaluation Of Handheld Point-of-Care-Ultrasound (POCUS) in Screening for Abdominal Aortic Aneurysm in Men : A Comparative, Cohort Study

OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld

Analysis of outcome of Lichtenstein groin hernia repair by surgeons-in-training versus a specialized surgeon

PURPOSE: Groin hernia repair is a common procedure in general surgery, and is taught to and performed by surgeons early in their training. The aim of this observational study was to compare hernia repair performance and results of surgical trainees with those of a specialized surgeon, to identify what factors may influence short and long-term outcome, and areas for improvement in surgical training

Interspecies variations in eyeblink conditioning

A central assumption in neuroscience is that learning mechanisms are conserved across species. Eyeblink conditioning, a cornerstone paradigm for studying associative learning and cerebellar function, has been widely used in humans and animal models alike. Yet direct cross-species comparisons remain rare. In this systematic review, we analyzed 484 eyeblink conditioning experiments reported in 271 s

Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in chronic limb-threatening ischaemia (SWEDEPAD 1) : a multicentre, participant-masked, registry-based, randomised controlled trial

BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial

Prostate cancer diagnostics: evolution over 30 years and the impact of education level – a prospective population-based study

Objective: The aim of this study is to describe how the use of diagnostic imagingfor prostate cancer (PCa) has evolved over time and to determine whether thereare any differences in access to diagnostic imaging, type of cancers detected, andmortality based on the education level of patients.Methods: 11,063 men were recruited between 1991 and 1996 and thenprospectively followed until 2020. All new

Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in patients with intermittent claudication (SWEDEPAD 2) : a multicentre, participant-masked, registry-based, randomised controlled trial

BACKGROUND: Drug-coated devices are widely used to reduce restenosis after lower limb revascularisation in patients with peripheral artery disease, but their effect on patient-centred outcomes remains unclear. We assessed the effect of paclitaxel-coated devices on clinically important outcomes in patients with intermittent claudication undergoing infrainguinal endovascular revascularisation.METHOD

The Contribution of BMI to a Young Child's Risk of Islet Autoimmunity Is Dependent on HLA-DR4-DQ8 Without HLA-DR3-DQ2

OBJECTIVE: Childhood obesity may impact the risk of islet autoimmunity (IA). The trajectory of BMI through childhood resembles the early peak incidence of first-appearing autoantibodies against insulin (IAA-first) but not GAD65 (GADA-first). We studied whether a child's BMI can impact the age-related risk of first-appearing IA phenotypes.RESEARCH DESIGN AND METHODS: We identified 7,724 children at

Den prediktiva förmågan hos SÖK-Observations instrument för tidig upptäckt av neuropsykiatriska funktionsnedsättningar hos barn

Bakgrund: Neuropsykiatriska funktionsnedsättningar uppstår oftast tidigt i barndomen, vilket gör tidig identifiering viktig för att stödja hälsosam utveckling. Det saknas ett bredare screeninginstrument för neuropsykiatrisk funktionsnedsättning för barn under två och ett halvt år. SÖK-Observations instrumentet utvecklades för att identifiera atypisk utveckling och autism hos barn vid 8-månaders hä

Energy hardship programmes : a systematic cross-country policy analysis of initiatives addressing equity and low-carbon energy services

Background: Energy hardship can be broadly understood as a situation in which individuals or households are unable to afford basic energy services necessary for sustaining their wellbeing. Despite conceptual challenges and overlaps with similar narratives (e.g., fuel poverty), the literature on energy hardship continues to expand. It represents a critical intersection with sustainable energy syste

Coupling green hydrogen production to community benefits : A pathway to social acceptance?

Hydrogen energy technologies are forecasted to play a critical supporting role in global decarbonisation efforts, as reflected by the growth of national hydrogen energy strategies in recent years. Notably, the UK government published its Hydrogen Strategy in August 2021 to support decarbonisation targets and energy security ambitions. While establishing techno-economic feasibility for hydrogen ene

Enhancing energy control stability under extreme conditions by integrating weather forecasts into ARLEM

Increasing the stability of energy management systems is crucial, especially when facing extreme weather events. A common approach to prevent sudden oscillations is the implementation of predictive models; however, this often requires more complex models and greater computational power. In this work, weather forecasts are integrated into an approach based on Adaptive Reinforcement Learning for Ene

IFNγ+ NKT-like cells are associated with increased incidence of atrial fibrillation in elderly women

Aims T cells are present in atrial tissue from atrial fibrillation (AF) patients. However, prospective studies of T cells and AF development are few. The current aim was to investigate if T-cell subsets are associated with the risk of developing AF. Methods and results T-cell subsets, measured by flow cytometry of cryopreserved mononuclear leucocytes isolated from blood at baseline, were analysed