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Optimisation of cultivation conditions in the industrial production of probiotics is crucial to reach a high-quality product with high probiotic functionality. The production process includes a fermentation step to produce biomass, accompanied by centrifugation to concentrate the cells. Subsequently, the cells are treated with stabilising solutions (lyoprotectants) before they are subjected to fre
The conserved ESX-1 type VII secretion system is a major virulence determinant of pathogenic mycobacteria, including Mycobacterium tuberculosis and Mycobacterium marinum. ESX-1 is known to interact with infected macrophages, but its potential roles in regulating other host cells and immunopathology have remained largely unexplored. Using a murine M. marinum infection model, we identify neutrophils
ObjectiveSex differences regarding the safety and efficacy of carotid revascularization in carotid artery stenosis have been addressed in several studies with conflicting results. Moreover, women are underrepresented in clinical trials leading to limited conclusions regarding the safety and efficacy of acute stroke treatments.MethodsA systematic review and meta-analysis was performed by literature
The relation between worship and gender is a hot topic in the Catholic Church. In recent decades, the debate has mostly been about breaking with patriarchal and male dominated liturgical forms and traditions. Yet, in Catholic traditionalist Catholic liturgy, due to the reform after the Second Vatican council, is considered to have lost much of its former masculine character. In my article, I addre
BACKGROUND: Exposure to adverse childhood experiences (ACE) have been found to have profound negative consequences on an individuals' health. Non-suicidal self-injury (NSSI) is a clinically complex and serious global health issue and is closely related to suicide attempts. Previous research has found associations between ACE and NSSI and suicide attempts in clinical samples. However, this associat
The cortical alterations underpinning the acquisition of motor skills remain debated. In this longitudinal study in younger adults, we acquired performance and neuroimaging (7T MRI) measures weekly over the course of 6 weeks to investigate neural changes associated with learning sequences of simultaneous finger presses executed with the non-dominant hand. Both the intervention group (n = 33) and t
Abnormal left ventricular contractile reserve (LVCR) is associated with adverse cardiac outcomes in different patient cohorts and might be useful in the detection of cardiomyopathy in childhood cancer survivors (CCS) after cardiotoxic treatment. The aim of this study was to evaluate LVCR by dobutamine stress echocardiography (DSE) combined with measures of myocardial strain in CCS previously treat
Flank wear VBmax remains one of the most essential and used metrics for measuring tool wear. VBmax is used to characterize tool wear rate, machinability of materials, the quality of machined surface. While VBmax measures the size of wear scar, the shape of the tool wear remains less used but not the least applicable for such characterization. However, quantification of the wear shape requires a mo
Studies of therapy-related AML (t-AML) are usually performed in selected cohorts and reliable incidence rates are lacking. In this study, we characterized, defined the incidence over time and studied prognostic implications in all t-AML patients diagnosed in Sweden between 1997 and 2015. Data were retrieved from nationwide population-based registries. In total, 6,779 AML patients were included in
This study examined journalists' perceptions regarding the legal system's ability to protect them against online harassment. By utilizing open-ended survey responses from respondents with varying levels of trust in the legal system, the findings suggested a need for increased technical proficiency, resources, and priority within the legal system to adequately address the issue. Additionally, a rec
Tungsten is a prime candidate material for use in plasma facing components in nuclear fusion reactors. This would entail weathering extreme conditions, such as high thermal loads and particle bombardment. It is of vital importance to understand how tungsten mechanically responds to these conditions, and how it is impacted by the defects that form. The current communication considers how the mechan
