Galectins are family of cytosolic proteins that function as both positive and negative modulators of various cell processes. Galectin-3 has an altered expression pattern in pathophysiological processes, such as cancer or chronic inflammation, which makes it an interesting target for pharmaceutical research. The treatment of galectin-3 ill-regulation was shown effective in serious conditions like i

This paper looks into the responses of cocoa farming households to a negative shock in the global cocoa price with regards to how they invest into the future of their children. The specific child outcomes of focus are child employment rates, school attendance, and household expenditure on schooling and related activities. A differences-in-differences approach is used in line with previous literatu

I takt med att det globala samhället blir större och större och mer och mer utvecklat, kräver mänskligheten mer energi. Idag kommer mycket energi runt om i världen från kol, olja och naturgas, så kallade icke-förnybara energikällor. Dessa är begränsade resurser som kommer att ta slut om vi använder dem ens i närheten av den utsträckning vi gör idag. Dessutom bidrar deras användning till en ökad väSyntheses of novel homo- and heteroleptic iron(II) N-heterocyclic carbene complexes have been pursued. The heteroleptic complexes contain donor-acceptor structures meant to enhance their sensitization activity when operating as a part in a dye sensitized solar cell by slowing down charge recombination. Syntheses of two related heteroleptic complexes were completed but require additional characteri

This report examines the concept of validating financial risk models, specifically Value-at-Risk, and compares the required regulatory tests with more advanced validation methods based on testing different martingale characteristics. The validation methods are considered in a classic backtesting scenario on a real custom portfolio, a Monte Carlo experiment to compare the empirical power on differe

Extracellulära vesiklar (EV) är membranbundna vesiklar som utsöndras från de flesta celler och släpps ut i biologiska vätskor. De är 30 - 5000 nm i diameter stora och innehåller biologiska molekyler som RNA, lipider och proteiner. De spelar en nyckelroll för kommunikationen mellan cellerna, så kallad, intercellulär kommunikation. EV är ett utmärkt medel för långdistans kommunikation mellan celler.The aim of this thesis was to reveal how nano-sized extracellular vesicles (EVs) isolated from human breast milk and Aascaris suum, parasitic worm incubation media interacts with hydrophilic, hydrophobic and DOPC surfaces and colloidally characterize EVs and EV fluids by determining their hydrodynamic radius and zeta potential. Dynamic Light Scattering (DLS) was used to determine the size and zet

A visit of an art exhibition can lead to feelings of frustration, exclusion, and not-being welcomed.Above all exhibitions of contemporary and modern art can due to the often conceptuel and abstract caracter of the artworks experienced as exclusive.As many researches has shown a museum visit become meaningful to us if a relation to what is seen can generates.Not just the consumption of cultural sup

Adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC) are the most common forms of lung cancer. These two subtypes of lung cancer are usually classified by visual inspection clinically. Our aim is to design an effective strategy based on convolutional neural networks to classify histopathology slides of these two types of lung cancer. With augmentation of the histopathology slides, different cl

Fruits and vegetables (F&V) waste in retail stores linked to consumer dissatisfaction has led to an increased interest in new preservation solutions to extend the shelf-life of fresh produce. In this study, the potential of controlled atmosphere (CA) combined with optimal temperature and relative humidity (RH) to extend the shelf-life of fruits and vegetables (F&V) in retail stores for shoReducing fruits & vegetables waste in retail stores with an innovative preservation solution Storing fruits and vegetables under controlled atmosphere and optimal temperature and humidity conditions could help improving consumer satisfaction and visual quality of fruits and vegetables in retail stores. The impact of an innovative solution on the shelf-life of fruits and vegetables and its env

This thesis addresses the research problem of volatile growth and in particular economic shrinking in developing countries. A single case study of Nigeria drawing on qualitative as well as quantitative data assesses four potential factors behind the country’s frequent and high shrinking rates between 1960 and 2017. The study finds a lack of structural transformation, productivity and diversificati

Colombia committed to reduce 20% of its emissions by 2030 in the framework of Paris Agreement. The study provides a systemic approach that considers the two main drivers of the emissions in the country to know how realistic is the mentioned intended National Determined Contribution (iNDC). It analyzes deforestation and road transport with a methodology that combines analyses of their current situa

Previous research has shown a link between investor sentiment and stock market movement, as well as the correlation of search engine queries and market volatility. This research aims to extend these findings by predicting the exact firm-level daily return of Apple and Amazon. The daily returns are predicted with an artificial neural network model. In theory, this model is able to learn similarly t

Växtprotein - lösningen för bekämpning av typ 2 diabetes? Mer än 400 miljoner människor i världen lider av diabetes typ 2 vilket gör det till en avde vanligaste folkhälsosjukdommarna enligt World Health Organisation (WHO). Thiazolidinediones (TZDs) används vid behandling av typ 2 diabetes då det höjer känsligheten för insulin. Kunskap om mekanismen kring TZD har tidigare varit begränsad vilket reMore than 400 million people in the world have type 2 diabetes, making it one of the most common diseases internationally according to the World Health Organization. Thiazolidinediones (TZDs) is used to treat type 2 diabetes since it increases the sensitivity of insulin in peripheral tissues. The knowledge about the mechanism how TZD works is limited which has resulted in patients getting serious

The master thesis is a collaboration between Trelleborg AB and the division of Production and Materials Engineering at Lund University, Faculty of Engineering. The objective of the thesis has been to analyse the current production system from a lean perspective, identify an area in need of improvement and generate concrete solutions for how the studied area can be improved in terms of cost, perfor

Examensarbetet gick ut på att undersöka lösningar på PLC till PLC-kommunikation mellan olika PLC-system. Ändamålet är att lägga grund till en produkt som kan ta hand om all kommunikation mellan flera maskiner med olika PLC-system på en fabrikslinje. Detutreddes vilka kommunikationsprotokoll som var lämpliga om PLC:er från Omron och Siemens användes. Efteråt undersöktes tredjeparts leverantörers l

This study investigates the lamella settlers in Ringsjö water treatment plant, Sweden, in terms of water movement and performance. The treatment plant has two blocks with differences in the flocculation and lamella settlers, where block 1 is not able to process the maximum designed flow rate without the addition of polymers. Through data analysis the problem was confirmed, showing that the two des

The purpose of this study is to discover the characteristics of consumer brand relationships between consumers and woke brands and thus contribute to the research field of consumer brand relations. This will be achieved by looking to the relationship in the context of postmodern consumers and specifically three purposively selected cases; Pepsi, Always and Gillette. The study is based on three ca

Titel: “Jag tar aldrig av mig jobbhatten”, en kvalitativ studie om hur chefer uppfattar sin psykosociala ohälsa. Nivå: Kandidatuppsats i Service Management, VT 2019 Universitet: Lunds Universitet, Campus Helsingborg, Institutionen för Service Management Handledare: Johan Alvehus Syfte och frågeställning: Syftet med denna studie är att undersöka den organisatoriska- och sociala ohälsa som exis

The behavior of a firm to engage in international innovation collaborations is characterized by complex relations that are identified at more than one level. However, less has been done to understand multilevel interactions and the effects of the national framework conditions. In this respect, this study elaborates a comprehensive set of country and firm-level variables, including the properties o

Bakgrund: Denna studie utforskar klienter, terapeuter och handledares erfarenheter av lekmannaterapi som traumabehandling i norra Uganda. Deltagarnas erfarenheter av vad som anses vara viktigt gällande implementering, planering och kontext utforskas tillsammans med vilka möjligheter och begränsningar deltagarna ser gällande detta behandlingsupplägg. Metod: 14 semistrukturerade intervjuer genomfördBackground: This study explored the experiences of clients, therapists and supervisors in regards to lay therapy as trauma treatment in Northern Uganda. The participants’ experiences of what is important in the implementation, planning and context for such treatment setup to be successful, as well as the potentials and limitations are explored. Method: A total of 14 semi-structured interviews were