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Aktivitetsanalys av enzymet PARP16 och dess koppling till cancerterapi Cancer är ett ord som troligtvis berör på ett eller annat sätt. Vare sig om man drabbas själv eller inte, så påverkar det alla om det så bara är en närstående till en som blivit drabbad. Studier inom proteinkemin har länge varit av stor betydelse då proteiner spelar en nyckelroll i DNA reparation. En enzymfamilj som är av storResearch in cancer is an ongoing project which not only includes finding more efficient treatment therapies, but also achieving a greater knowledge of how proteins of interest are targeted by inhibitors. Furthermore, research in this field can give us greater knowledge about the development of cancer cells if they are modified. One enzymatic protein family, the PARPs, has been widely studied for d

Purpose: The purpose of this thesis is to understand how a privatization process affects a company’s institutional logic in the presence of path dependence mechanisms, and to delineate the implications this has on the firm’s value creation strategy. Theoretical Perspectives: This thesis builds upon general ownership theories from the perspective of institutional logics. To these perspectives, path

Patent law has been prevalent in climate change discussions, as a factor linking technology, Intellectual Property Rights (IPRs) and the climate crisis. The inventive step, its set threshold and the environmental benefits for the assessment of its current state, are one of the paths where patent law can act as a potential promoter of green technologies. This paper aims to asses how patent law can

Euroscepticism is an old, but nevertheless still dangerous, phenomena for the European Union and for further European integration. Now more than ever, in the wake of Brexit and other crises of the 2000th century, public Euroscepticism is on the rise throughout the European Union member states. Notably, it has been determined that the rise is particularly large within rural areas. The residents of

This thesis scrutinises the concept of the European Super League in light of EU competition law and aims to provide an answer to the question whether the rules on prior authorisation by FIFA and UEFA infringe Article 101 and/or Article 102 TFEU, and whether the European Super League itself infringes Article 101 TFEU. The outcome of this thesis is that both questions must be answered in the affirma

This research aimed to explore the experiences of Lagos State residents during COVID-19 and the relationship between COVID-19 reportage in Lagos State and ethnic inter-relationship. The goal is to understand media influence in a society from the perspectives of people directly influenced by the COVID-19 media frames. This thesis is the first research to explore ethnic polarization in Lagos State w

Patients under the jurisdiction of the Scania Region of Sweden have since 2014 had the ability to choose their care provider regarding opioid substitution treatment, OST. This ability to choose has come from the advancements of the New Public Management, NPM, within Swedish health care. The goal of which has been to increase the availability of OST, as well as to strengthen the patient's auton

Spelreklam utgör idag en majoritet av all marknadsföring som sker. Måttfullhetskravet i spellagen utgör ett krav att spelaktörer ska iaktta måttfullhet vid marknadsföring av spel till konsumenter. Måtfullhetskravet har idag en vägledning som innebär rekommendationer och riktlinjer. Måttfullhetskravet ska förbli flexibelt i spellagen och vid sanktioner ska en helhetsbedömning göras. Detta lämnar 15Gambling advertising today constitutes a majority of all marketing that takes place. The requirement of moderation in the Gambling Act is a requirement that gambling players must observe moderation when marketing games to consumers. The requirement of moderation today has a guide that entails recommendations and marketing guidelines. The moderation requirements must remain flexible in the Gambl

Syfte Syftet med föreliggande studie var att undersökte om det finns en skillnad i upplevd rösthälsa i åldersgrupperna 65-70, 71-75 och 76-80, och ett samband mellan upplevd rösthälsa och omfattning och upplevelse av social delaktighet bland individer mellan 65 och 80 år. Metod En webbenkät avseende upplevd rösthälsa och social delaktighet skapades för allmänt friska deltagare som för närvarande Purpose The aim of this study was to examine whether there was a difference in subjective vocal health in age groups 65-70, 71-75 and 76-80, and an association between subjective vocal health and the extent and experience of social participation among individuals aged 65 to 80 years. Method An online questionnaire regarding subjective vocal health and social participation was distributed to subj

Circular economy has recently become a central part of European policy, bridging the environmental and economic policy domains closer than ever in an attempt to fulfil enhanced environmental ambitions. As economic operators seek to adopt innovative solutions, the issue of how established legal frameworks hamper or facilitate them becomes central. This thesis examines this point in relation to on

Denna masteruppsats baseras på en jämförande undersökning beträffande egennamn och benämningar i den norska och den svenska översättningen av J. K. Rowlings Harry Potter and the Philosopher’s Stone (1997). Syftet med denna uppsats är att undersöka skillnaderna i översättningsval mellan språken vad gäller kategorierna egennamn och benämningar samt om valen varierar beroende på kategori. Uppsatsen b

Transylvania’s countryside, characterized by a mostly agrarian society with a rich multicultural heritage is being threatened by Romania’s tendencies of chaotic modernization and rapid urbanization. This research aims to find a viable solution for sustaining the cultural, natural, and social environment in rural Transylvania, by analysing the potential of tourism development. Integrated Rural Tour

Bakgrund: Kontroll av gastrisk residualvolym (GRV) via aspiration sker på intensivvårdsavdelningar med syfte att säkerställa tillräcklig nutritionstillförsel och utvärdera risken för komplikationer relaterade till enteral nutrition (EN). Studier visar på oenighet huruvida stor GRV faktiskt ökar risken för negativa effekter, dessutom varierar rutiner för GRV-mätning gällande teknik, frekvens och mBackground: Checking gastric residual volumes (GRV) by aspiration is a method practiced on intensive care units with the purpose of lowering the risk of complications due to enteral nutrition (EN) as well as to ensure adequate delivery of EN. Studies have shown disagreement whether large GRVs increase the risk of negative effects, also the methods of measuring vary by technique, frequency and amou

This study seeks to explore the ways Syrian-Armenian migrants in Armenia perceive and narrate homeland, home, and belonging in their post-migration setting. Through the personal stories and experiences of the participants, this study aims to contest and deconstruct the assumptions about the fixed nature of homeland, home, and belonging. While doing so, this thesis relies upon the contemporary theo

States or regions conclude IIAs to protect and promote foreign investments, among other things, by prohibiting states’ from ‘taking’ or adopting measures equivalent to ‘taking’ the foreign investors’ property, known as expropriation. However, the state needs regulatory space, but how much is unclear and controversial. The newly concluded EU and Singapore FTA and IPA are taking a new approach to th

For decades international research has shown that children in out-of-home care have poor dental health compared to their peers. Although new and more rigorous health regulations have been introduced to the Swedish child welfare authority system, this has not been enough to solve the problem. The aim of this study was to examine how child welfare secretaries relate to regulations concerning their r

Studiens syfte är att analysera och skapa en förståelse för hur fenomenet arbetsgemenskap påverkats när arbetet förskjutits till distans hemifrån under Covid-19 pandemin. För att få en nyanserad förståelse för valt forskningsfenomen har anställda både från privat- och offentlig sektor inkluderats. Studien utgår från en kvalitativ metod med semistrukturerade djupintervjuer för att fånga individers

This thesis addresses the role of the corporate purpose in strategic financial communication from the perspective of investor relations professionals (IRPs) with particular reference to their sensemaking process. Strategic financial communication increasingly includes intangible assets that contribute to the value of the company. At the same time, more and more companies are publishing corpora

Schools and libraries in Sweden strive to be inclusive of all groups in society, particularly people with disabilities. Both actors are responsible for making knowledge available to all, as knowledge is a necessary precondition for a democratic society that is both inclusive and well-functional. This study was carried out on behalf of the Svane and Hedda schools in Lund, which will be co-located