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Clinical parameters predicting complications in native kidney biopsies

Background. Renal biopsies are essential in nephrology but they are invasive and complications can occur. The aim of this study was to explore clinical parameters that can be used as predictors for biopsy complications. Methods. Clinical parameters such as demographics, biopsy indications, serology, comorbidities and clinical chemistry were retrieved from a regional biopsy registry between 2006 an

Museomics : Phylogenomics of the Moth Family Epicopeiidae (Lepidoptera) Using Target Enrichment

Billions of specimens can be found in natural history museum collections around the world, holding potential molecular secrets to be unveiled. Among them are intriguing specimens of rare families of moths that, while represented in morphology-based works, are only beginning to be included in genomic studies: Pseudobistonidae, Sematuridae, and Epicopeiidae. These three families are part of the supe

Common Susceptibility Loci for Male Breast Cancer

BackgroundThe etiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is unknown. A previous genome-wide association study of MBC identified 2 predisposition loci for the disease, both of which were also associated with risk of FBC.MethodsWe performed genome-wide single nucleotide polymorphism ge

The pentatricopeptide repeat protein EMP603 is required for the splicing of mitochondrial Nad1 intron 2 and seed development in maize

Intron splicing is an essential event in post-transcriptional RNA processing in plant mitochondria, which requires the participation of diverse nuclear-encoded splicing factors. However, it is presently unclear how these proteins cooperatively take part in the splicing of specific introns. In this study, we characterized a nuclear-encoded mitochondrial P-type pentatricopeptide repeat (PPR) protein

Democratic emancipation in Scandinavian offender rehabilitation : – Between policy discourse and actual practice

This PhD project balances an interest in social work and its prospects for deliv-ering emancipation or relief from stigma, etc. through motivational agency, on the one hand, with an attentiveness to recent developments in Scandinavian criminal policy, on the other. In my attempts at »bridging« these interests I have come to focus on offender rehabilitation. In this short paper I shall present the

Agreement of the modified Medical Research Council and New York Heart Association scales for assessing the impact of self-rated breathlessness in cardiopulmonary disease

Background: The functional impact of breathlessness is assessed using the modified Medical Research Council (mMRC) scale for chronic respiratory disease and with the New York Heart Association Functional Classification (NYHA) scale for heart failure. We evaluated agreement between the scales and their concurrent validity with other clinically relevant patient-reported outcomes in cardiorespiratory

Bygd, by och bostad runt Uppåkra : Landskapet med sin centralplats

Uppåkra har länge framstått som en solitär i ett tomt landskap. Bakgrunden till denna uppfattning, snarare än realitet, kommer av det faktum att få arkeologiska undersökningar har gjorts i centralplatsens närhet. Inom en fem kilometers radie runt Uppåkra har emellertid flera undersökningar utförts under 2000-talet inom uppdragsarkeologin. Dessa har skapat en hälsosam kontrast till den fyndrika pla

Phosphorylation and glycosylation isoforms of bovine κ-casein variant E in homozygous Swedish Red cow milk by liquid chromatography-electrospray ionization mass spectrometry

Variations in the phosphorylation and glycosylation patterns of the common κ-casein (CN) variants A and B have been explored, whereas studies on variant E heterogeneity are scarce. This study reports for the first time the detailed phosphorylation and glycosylation pattern of the κ-CN variant E in comparison with variants A and B. Individual cow milk samples representing κ-CN genotype EE (n = 12)

From the Guest Editors Splintering Urbanism at 20 : Mapping Trajectories of Research on Urban Infrastructures

Stephen Graham and Simon Marvin’s Splintering Urbanism: Networked Infrastructures, Tech- nological Mobilities and the Urban Condition (2001) brought the study of infrastructure to the core of urban studies and inspired the “infrastructural turn” in the social sciences more widely. The book catalyzed a rich trove of research on how technology and society are impli- cated in the production of contem

The external effects of offshoring on job security in SMEs

We investigate the effects of offshoring on job security using matched employer-employee data from Sweden. Between 1997 and 2011, the share of offshoring firms fell from around 25 to 22% while offshoring per worker within offshoring firms almost doubled. We use this variation to contribute to the literature by examining the effects of the neighboring firms’ offshoring (external offshoring) on job

Understanding secondary nucleation of the amyloid β peptide

Alzheimer’s Disease (AD) is a devastating neurodegenerative disease associated with massive neuronal cell death during its pathology. The involvement of the amyloid β 42 (Aβ42) peptideand its role in neurotoxicity is now well established. It is known that the production of oligomers during the aggregation of Aβ42 into highly ordered fibrils is responsible for neuronal cell death. However, the effo

Long-term outcomes after fenestrated endovascular aortic repair for juxtarenal aortic aneurysms

Objective: Fenestrated endovascular aortic aneurysm repair (FEVAR) for juxtarenal aortic aneurysm (jAAA) disease is safe and effective with good short- and mid-term outcomes. The durability issues have mainly focused on the proximal and distal seal and target vessel (TV) instability, and long-term data are scarce. In previous studies, we have reported the short-term outcomes after FEVAR and compar

Differential associations between neocortical tau pathology and blood flow with cognitive deficits in early-onset vs late-onset Alzheimer’s disease

Purpose: Early-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease (LOAD) differ in neuropathological burden and type of cognitive deficits. Assessing tau pathology and relative cerebral blood flow (rCBF) measured with [18F]flortaucipir PET in relation to cognition may help explain these differences between EOAD and LOAD. Methods: Seventy-nine amyloid-positive individuals with a cl

Legacy of the disowned : Findings ambátts in High Medieval Scania and Östergötland through ceramic production

rapidly and on a large scale, judging from the very short introduction phase for late Slavic pottery and the absence of hybrid forms between this tradition and the local Scandinavian ware. Late Slavic ware became a Scanian cultural trait after only one generation; this tradition is today called “Baltic ware”, as it was produced outside the Slavic area by an increasing number of local potters. AfteThe existence of slavery in Viking-Age and high medieval Scandinavia is accepted as a fact. Law codes, literary sources and some few burials vouch for that. It is, however, more complicated to ascertain regional differences in the use of slaves, their ethnic identities and geographical distribution, as well as changes in the intensity of their exploitation over time. A new source, household potter

Beyond Demonstrators—tackling fundamental problems in amplifying nature-based solutions for the post-COVID-19 world

Nature-based Solutions (NbS) are currently promoted as a panacea for improving human-nature relations. Yet the way of amplifying and mainstreaming NbS beyond scientific demonstrator projects into policy contexts is still bearing shortcomings, in particular in the uncertain futures of a post-COVID-19 world. Successful NbS amplification may be achieved by (1) using multi-scalar action to balance dif

Post-Truth Implications for COVID-Era Healthcare : Verification, Trust, and Vaccine Skepticism

Why, in the midst of the global Coronavirus pandemic, do so many people seem resistant to the recommendations of established medical experts? In this chapter, I explore possible structural causes of this resistance in the U.S. context. I argue that in the “post-truth” era, attempts to encourage people to wear face masks and get vaccinated confront challenges pertaining to how scientific knowledge