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Departure deviations from shunting yards impact the reliability of rail freight services and the punctuality of a railway network. Therefore, the statistical analysis of these deviations are necessary for improving the operation of trains in mixed-traffic networks. In our paper, we conduct a detailed statistical analysis of departure deviations considering individual shunting yards characteristics

Background: Despite their vulnerability to the toxic effects of certain metals, biomonitoring data on adolescents are limited. In the present study, we assessed blood concentrations of toxic metals (cadmium [Cd], total mercury [Hg], and lead [Pb] in a national representative sample of Swedish adolescents. We also examined the associations of Cd, total Hg and Pb with habitual intakes of major energ

Musical performance is a multimodal experience, for performers and listeners alike. This paper reports on a pilot study which constitutes the first step toward a comprehensive approach to the experience of music as performed. We aim at bridging the gap between qualitative and quantitative approaches, by combining methods for data collection. The purpose is to build a data corpus containing multimo

”Vilken svensk författare motsvarar Japans Yukio Mishima, Tysklands Ernst Jünger och Frankrikes Louis Ferdinand Céline?”, frågar en svensk debattör och forskare i en artikel 2016. Till dessa om än famösa så välkända namn adderar frågeställaren Norges Knut Hamsun respektive Finlands Örnulf Tigerstedt. Med denna fråga som utgångspunkt granskas och prövas i artikeln såväl nazistiska partiledare och n"Which Swedish author could be compared to Yukio Mishima of Japan, Ernst Jünger of Germany and Louis-Ferdinand Céline of France?”, a Swedish debater and researcher asks in an article in 2016. To these well-known, even if infamous, authors, Knut Hamsun of Norway and Örnulf Tigerstedt of Finland are added. With the question raised, Nazi party leaders and Nazi followers as well as national poets of S

Near ambient pressure scanning photoelectron microscopy adds to the widely used photoemission spectroscopy and its chemically selective capability two key features: (1) the possibility to chemically analyse samples in a more realistic gas pressure condition and (2) the capability to investigate a system at the relevant spatial scale. To achieve these goals the approach developed at the ESCA Micros

It is of great importance to understand how terrestrial ecosystems will respond to global changes. However, most experimental approaches have focused on single factors. In natural systems, moisture and temperature often change simultaneously, and they can interact and shape microbial responses. Even though soil moisture and temperature are very important factors controlling microbial activity, the

Objectives: This study sought to compare interrupted and uninterrupted oral anticoagulant therapy (I-OAC vs. U-OAC) in patients on OAC undergoing percutaneous coronary intervention. Background: There is a paucity of data regarding the optimal peri-procedural management of OAC-treated patients. Methods: In the SWEDEHEART registry, all patients on OAC who were admitted acutely and underwent percutan

Background: Treatment adaptation based on tumour biomarker response during radiotherapy of prostate cancer, could be used for both escalation and de-escalation of radiation doses and volumes. To execute an adaptation involving extension of treatment volumes during radiation can however be restricted by the doses already delivered. The aim of this work was to develop a treatment planning method tha

Background: PAM50 breast cancer intrinsic subtyping adds prognostic information in early breast cancer; however, the role in metastatic disease is unclear. We aimed to identify PAM50 subtypes in primary tumors (PTs) and metastases to outline subtype changes and their prognostic role. Methods: RNA was isolated from PTs, lymph node metastases (LNMs), and distant metastases (DMs) in metastatic breast

PurposeTo validate a candidate instrument, to be used by different professionals to assess image quality in digital mammography (DM), against detection performance results.MethodsA receiver operating characteristics (ROC) study was conducted to assess the detection performance in DM images with four different image quality levels due to different quality issues. Fourteen expert breast radiologists

Maternal obesity may lead to epigenetic alterations in the offspring and might thereby contribute to disease later in life. We investigated whether a lifestyle intervention in pregnant women with obesity is associated with epigenetic variation in cord blood and body composition in the offspring. Genome-wide DNA methylation was analyzed in cord blood from 208 offspring from the Treatment of Obese P

Preeclampsia (PE) is a pregnancy disorder associated with placental dysfunction and elevated fetal hemoglobin (HbF). Early in pregnancy the placenta harbors hematopoietic stem and progenitor cells (HSPCs) and is an extramedullary source of erythropoiesis. However, globin expression is not unique to erythroid cells and can be triggered by hypoxia. To investigate the role of the placenta in increasi

AbstractObjective: To investigate the time to maximal platelet inhibition after an oral loading dose of ASA. The effect of ex vivo reversal platelet inhibition by desmopressin(DDAVP) was also studied.Methods: Ten healthy volunteers were given a 300 mg ASA-tablet. Blood was sampled at 0, 15, 30, 60, 120, and 180 minutes. DDAVP was added to the samplestaken at 120 minutes.Samples were analyzed with Objective: To investigate time to maximal platelet inhibition after an oral loading dose of ASA. The effect of ex vivo reversal platelet inhibition by desmopressin (DDAVP) was also studied. Methods: Ten healthy volunteers were given a 300 mg ASA-tablet. Blood was sampled at 0, 15, 30, 60, 120 and 180 minutes. DDAVP was added to the samples taken at 120 minutes. Samples were analysed with a Multi

OBJECTIVE: To investigate the effect on pregnancy outcome of integrating a comprehensive management plan for patients with type 1 diabetes (T1D) into the World Health Organization universal maternal care infrastructure. RESEARCH DESIGN AND METHODS: A comprehensive preconception-to-pregnancy management plan for women with T1D was implemented in 11 centers from 8 Chinese cities from 2015 to 2017. Se

This paper discusses the future of migrants with acute heart problems and without permanent permission to remain in the country where they are seeking asylum. What does the country they have traveled to owe them? Specifically, what healthcare services are they entitled to? This may seem a niche problem, but numbers of migrants with acute heart problems could increase in the future. Besides, simila

Beginning in the 1890s, workers’ associations and social-democratic activists in Sweden developed a series of People's Parks (Folkets parker) that extended across the length and breadth of the country. By the the mid-twentieth century, nearly every city, town, and village boasted its own People's Park. Built for relaxation and recreation, as well as for political agitation, Folkets parker also rep