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BACKGROUND AND PURPOSE: The treatment landscape for patients with advanced non-small cell lung cancer (NSCLC) has evolved significantly since the introduction of immunotherapies. We here describe PD-L1 testing rates, treatment patterns, and real-world outcomes for PD-(L)1 inhibitors in Sweden. MATERIALS AND METHODS: Data were obtained from the Swedish National Lung Cancer Registry for patients wit
Introduction: Early recognition of pain in children is crucial, and their self-report is the primary source of information. However, communication about pain in healthcare settings can be challenging. For non-verbal communication regarding different symptoms, children prefer digital tools. The electronic Faces Thermometer Scale (eFTS) utilizes a universal design with colors, face emojis, and numbe
A continuously growing and mutating market with increasing demands on environmental sustainability, illuminated by unraveling environmental threats, highlights the need for greater resource efficiency in modern manufacturing industries. Machining has become pivotal in the pursuit of sustainability given its superior efficiency in manufacturing of metallic products. In theory, the efficiency of a m
In medical and biomedical education, traditional teaching methods often struggle to engage students and promote critical thinking. The use of AI language models has the potential to transform teaching and learning practices by offering an innovative, active learning approach that promotes intellectual curiosity and deeper understanding. To effectively integrate AI language models into biomedical e
We explain how the accelerating field amplitude and phase vary with modulator voltage in pulsed radio frequency high-power amplifiers based on klystron tubes. Changes in modulator voltage give rise to correlated changes of amplitude and phase, affecting the properties of the accelerated beam, in particular energy, arrival time, and bunch duration. We show, both theoretically and experimentally, th
Objective. To examine the changes in health-related quality of life (HRQoL) in patients with coronary artery disease (CAD) in terms of age, gender, and treatment strategy in Iran. Methods and Materials. Forty-nine patients responded to the Iranian version of the 36-item short form (SF-36) questionnaire to evaluate the HRQoL at first and third year after treatment. The paired and independentWilcoxo
This chapter provides an overview of current research on thinking-for-speaking and second language acquisition. The Thinking-for-Speaking hypothesis (Slobin, 1996) posits that whilst in the process of producing speech, speakers channel their attention according to the linguistic categories of their language. As a result, speakers of different languages think differently during speech production. W
The emergence of short video (e.g. TikTok) provides a new avenue for destination marketing. However, limited research exists on short ice-snow destination videos, which are significant for Nordic winter tourism marketing. Drawing on a model based on parasocial interaction theory, this study finds that ice-snow celebrity attachment positively predicts Chinese tourists’ parasocial interaction, enjoy
This chapter reviews the available empirical evidence for a universal metaphoric structure such as TIME IS SPACE and its effects on temporal cognition in L2 users. The chapter covers previous experimental evidence that lends support to the psychological reality of the TIME IS SPACE metaphor, while also revealing cross-linguistic differences in how this fundamental metaphor is instantiated across t
The temporal focus hypothesis (TFH) entails that individuals who value the past tend to conceptualize it in front, whereas individuals who value the future tend to map the future in front instead (de la Fuente et al., 2014). This varies as a function of culture, individual differences, and context. Here, we extend this line of inquiry by testing a contextual variable, namely COVID-19 quarantine st
Mapping of algae on facades and difficult-to-reach parts of tall buildings is demonstrated using a low-cost 3D-printed hyperspectral fluorescence lidar (HSFL).The 3D-printed HSFL has the potential for rapid and cost-effective remote assessment of algae.
Green inventory management is concerned with the overarching question of how to efficiently manage inventories and thereby material flows in supply chains, considering both economic and environmental consequences, commonly translated into costs and emissions. As inventory decisions are interlinked with production and transportation decisions, a total cost and emissions perspective is important to
Purpose: This paper aims to challenge the view of Sweden’s climate leadership by problematizing its domestic climate adaptation governance and highlighting the need for a more holistic view of adaptation. The paper highlights aspects that are troublesome for not only the built environment along coastlines but also the future of Sweden’s standing as a climate leader. The paper concludes with recomm
Galectin-3 (Gal-3) is a multifunctional protein that plays a pivotal role in the initiation and progression of various central nervous system diseases, including cancer. Although the involvement of Gal-3 in tumour progression, resistance to treatment and immunosuppression has long been studied in different cancer types, mainly outside the central nervous system, its elevated expression in myeloid
The first example of a material capable of spatiotemporal catch and release of singlet oxygen (1O2) in gel phase is presented. Several low molecular weight organogelators based around an oxotriphenylhexanoate (OTHO) core are developed and optimized with regard to; their gelation properties, and ability of releasing 1O2 upon thermal and/or photochemical external stimuli, in both gel phase and solut
The concentration of colored dissolved organic matter (CDOM) in lakes is strongly influenced by climate, land cover, and topographic settings, but it is not known how drought may affect the relative importance of these controls. Here, we evaluate the controls of CDOM during two summers with strongly contrasting values of the Palmer drought index (PDI), indicating wet vs. dry conditions. We hypothe
Representations of the slim body have traditionally been at the centre of scholarly interest in dieting culture, whereas food often remains a shadowy presence compared with more persistent themes of body discipline, slenderness and anti-fat messages. This article offers a different perspective on weight-loss dieting, placing food at the very centre of the analysis. By examining different diets in
Background: There has been a notable decrease in antibiotic prescribing in the last thirty years in Sweden. Little is known about factors influencing antibiotic prescribing over several years. Objective: To compare primary care physicians who, over time, reduced their antibiotic prescribing for respiratory tract infections with those who remained either high or low prescribers regarding potentiall
