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Long-term biokinetics and radiation exposure of patients undergoing 14C-glycocholic acid and 14C-xylose breath tests.

The (14)C-glycocholic acid and (14)C-xylose breath tests are clinically used for the diagnosis of intestinal diseases, such as bacterial overgrowth in the small intestine. The two tests have in earlier studies been thoroughly evaluated regarding their clinical value, but due to the long physical half-life of (14)C and the limited biokinetic and dosimetric data, which are available for humans, seve

Everolimus With Reduced Calcineurin Inhibitor in Thoracic Transplant Recipients With Renal Dysfunction: A Multicenter, Randomized Trial.

BACKGROUND.: The proliferation signal inhibitor everolimus offers the potential to reduce calcineurin inhibitor (CNI) exposure and alleviate CNI-related nephrotoxicity. Randomized trials in maintenance thoracic transplant patients are lacking. METHODS.: In a 12-month, open-labeled, multicenter study, maintenance thoracic transplant patients (glomerular filtration rate >/=20 mL/min/1.73m and 1 year

Vi ventilerar felaktigt : Anpassa efter årstiden och ändra normvärdena / Så hindras markfukten: Tätt under platta på mark är bästa metoden

Normvärdet 0,5 luftomsättningar per timme är för lågt under den varma årstiden och onödigt hög på vintern. Ventilationen bör variera med årstiden. Helst bör styrningen ske automatiskt via ånghalten i luften. Rekommendationerna i SBN och nuvarande Nybyggnadsregler om hur platta på mark bör utföras har varierat under åren. Men konsekvent har man prioriterat uttorkning av byggfukt och därmed dragit

Initial and long-term effects of enhanced external counterpulsation in patients with refractory angina pectoris

Symptom relief through spinal cord stimulation (SCS) based on the gate-control theory and enhanced external counterpulsation (EECP) through improved coronary perfusion is two treatments in angina pectoris refractory to medication and surgery. The overall aim was to evaluate and compare the initial and longterm effects, utilization and cost of EECP compared to SCS. The effects were also compared to

Nuclear Janus-Activated Kinase 2/Nuclear Factor 1-C2 Suppresses Tumorigenesis and Epithelial-to-Mesenchymal Transition by Repressing Forkhead Box F1.

Progression to metastasis is the proximal cause of most cancer-related mortality. Yet much remains to be understood about what determines the spread of tumor cells. This paper describes a novel pathway in breast cancer that regulates epithelial-to-mesenchymal transition (EMT), motility, and invasiveness. We identify two transcription factors, nuclear factor 1-C2 (NF1-C2) and Forkhead box F1 (FoxF1

A methodological contribution to the assessment of nonword repetition-a comparison between children with specific language impairment and hearing-impaired children with hearing aids or cochlear implants.

Poor nonword repetition is considered as a clinical marker of specific language impairment (SLI). In children with expressive language problems, the analysis and scoring procedures are often insufficiently described. We argue for a combined analysis of segmental and suprasegmental accuracy in nonword repetition tasks as well as an appreciation of gender differences. The view is taken based on empi

The European Waste Hierarchy: From the Socio-materiality of Waste to a Politics of Consumption

The production of municipal solid waste is one central concern for environmental policy, and the socio-materiality of waste – how the organisation of waste streams affects households and other waste producers – is an important issue for sustainability. This article shows how the application of European Union waste policy through its waste hierarchy affects the socio-material status of waste. The w

Association of MC1R Variants and Host Phenotypes With Melanoma Risk in CDKN2A Mutation Carriers: A GenoMEL Study.

Background Carrying the cyclin-dependent kinase inhibitor 2A (CDKN2A) germline mutations is associated with a high risk for melanoma. Penetrance of CDKN2A mutations is modified by pigmentation characteristics, nevus phenotypes, and some variants of the melanocortin-1 receptor gene (MC1R), which is known to have a role in the pigmentation process. However, investigation of the associations of both

The Source of Jus Cogens Obligations: How Legal Positivism Copes with Peremptory International Law

If legal positivists wish to sustain their account of the international legal system, arguably, they have yet to explain how jus cogens obligations can derive from the usual norm-creating processes recognized by international law. This article provides such an explanation exactly. The explanation builds on the distinction between first order rules of jus cogens (commanding or prohibiting some cert

Även Sverige behöver en ny filmhistoria

Kulturartikel om ett planerat svenskt projekt att skriva en ny svensk filmhistoria och en möjlig förebild i det amerikanska projektet History of the American Cinema på University of California Press.