Purpose: Neurofilament light (NfL) is a biomarker reflecting neurodegeneration and acute neuronal injury, and an increase is found following hypoxic brain damage. We assessed the ability of plasma NfL to predict outcome in comatose patients after out-of-hospital cardiac arrest (OHCA). We also compared plasma NfL concentrations between patients treated with two different targets of arterial carbon

This report presents an integrated simulation-based approach to study the on-site production of concrete frameworks by considering the multiple effects of weather on work task productivity and concrete curing process. The suggested approach enable to systematically study how different weather conditions and the use of climate-improved concrete in combination with different methods to shield concre

The construction workflow of in-situ concrete frames in multi-storey residential buildings is highly complex and dynamic. Discrete-event simulation (DES) offers capabilities to model and analyse such complexity. Although DES has successfully been used by researchers in a wide range of construction-related applications there are not many examples demonstrating how different simulation outputs (time

The erection process of in situ cast concrete frameworks in multi-storey housing consists of multiple on site activities in which labour, equipment and materials are interacting in a complex system. Studies have shown that the current process involves a wide range of non-value adding activities, resulting in poor process efficiency. This paper presents a model developed for discrete-event simulati

In Sweden and elsewhere in the world the construction industry has encountered criticism due to its lower productivity gains in comparison to other industries. This is why continual improvement of processes and forms of cooperation are important, as is utilisation of technologies giving greater efficiencies. The focus in Sweden has mainly been on the construction of multifamily buildings, both bec

Ribonucleotide reductase (RNR) is a central enzyme for DNA building block synthesis. Most aerobic organisms, including nearly all eukaryotes, have class I RNRs consisting of R1 and R2 subunits. The catalytic R1 subunit contains an overall activity site that can allosterically turn the enzyme on or off by the binding of ATP or dATP, respectively. The mechanism behind the ability to turn the enzyme

This paper studies the Swedish experience of the international crisis of 1907, which is often compared with the crisis of 2008. By constructing a new dataset from previously unanalyzed monthly bank-level data, we document high-frequency changes in bank outcomes throughout the 1907 crisis. While distressed banks suffered substantial withdrawals of foreign funds and liquid domestic liabilities, we s

Automated consistent software updating is challenging for distributed internet-of-things applications. We are developing a solution based on allowing several versions of the software to coexist on the same device, so that new and old software can be gradually phased in and out. We demonstrate our solution using a smart-city application for preventing thefts of bike batteries.

Human dependence is a phenomenon with above all negative connotations. We tend to associate it either with addiction or an economic, social and emotional lack of independence and view it as an impediment to women’s liberation. Dependence has been viewed as mutually exclusive to freedom. This is particularly the case in a country like Sweden, where independence is built in to the societal system so

Educational and income gradients in health are well established in the literature but there is need for a better understanding of how mental health inequalities change over time, and what drives the development. We aim to study how psychiatric diagnosis and its income-related inequality have changed over time in Sweden and to make a first attempt at disentangling the development by decomposing any

Photonic materials for high-temperature applications need to withstand temperatures usually higher than 1000 °C, whilst keeping their function. When exposed to high temperatures, such nanostructured materials are prone to detrimental morphological changes, however the structure evolution pathway of photonic materials and its correlation with the loss of material's function is not yet fully underst

Mortality differentials by socioeconomic status (SES) are among the most pervasive facts of contemporary demography. However, while the mortality gradient by income, class and education is well-established for the period after 1970, evidence regarding the origins of the gradient is still scarce. The aim of this thesis is to explore the development of SES differences in all-cause and cause-specific