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This research seeks to identify critical factors that influence the success to implementing design thinking in the prototype design process within SMEs clusters in developing countries like Bolivia. The determinants of design thinking implementation are generally underexplored, therefore exhibiting its innovative point and contributing to the relevant debate in the field of design, as well as orga
The closed-cycle hydrogen-fueled argon power cycle is a zero emissions concept that combines a carbon-free fuel with argon as a diluent replacement for nitrogen. The lack of nitrogen in the argon power cycle results in zero NOx emissions on an internal combustion engine platform. There is also massive efficiency improvement because argon is monatomic and has a very high ratio of specific heats. HoThe closed-cycle hydrogen-fueled argon power cycle is a zero emissions concept that combines a carbon-free fuel with argon as a diluent replacement for nitrogen. The lack of nitrogen in the argon power cycle results in zero NOx emissions on an internal combustion engine platform. There is also massive efficiency improvement because argon is monatomic and has a very high ratio of specific heats. Ho
This is a study about conversion in the letter to the Colossians. It argues that the recipients of the letter constituted a group primarily made up of non-Jews who had responded to the message about a Jewish Messiah and formed an association-like group dedicated to his worship. The study spans many fields of research, including New Testament Studies, Archaeology, and modern Conversion Studies. As
Ur förordet:Designen på vardagsnära produkter spelar en viktig roll för att underlätta energi- och resursbesparande beteende. Denna rapport är baserad på projektet ”Standardalternativ som potentiellt verktyg för att främja energieffektivt beteende”. Projektet syftar till fördjupad förståelsen för hur standardalternativ påverkar användare och hushållens energianvändning genom designen. Resultaten g
Background: Inhibition of factor Xa (FXa) by tissue factor pathway inhibitor α (TFPIα) is potentiated by FV-Short and protein S. The C-terminus of TFPIα is important for formation of the TFPIα/protein S/FV-Short complex. It contains a hydrophobic sequence (LIKT). The purpose was to investigate the importance of the LIKT sequence.Methods: Two TFPIα C-terminal peptides were synthesized, one wild-typBackground: Inhibition of factor Xa (FXa) by tissue factor pathway inhibitor α (TFPIα) is potentiated by FV-Short and protein S. The C-terminus of TFPIα is important for formation of the TFPIα/protein S/FV-Short complex. It contains a hydrophobic sequence (LIKT). The purpose was to investigate the importance of the LIKT sequence.Methods: Two TFPIα C-terminal peptides were synthesized, one wild-typ
Protein-stabilized oil–water emulsions are increasingly encountered in biorefinery and agro-industrial streams, yet their treatment by membrane filtration remains limited by insufficiently understood fouling mechanisms. Unlike synthetic surfactants, proteins exhibit intrinsic charge regulation and environment-dependent interfacial behavior that strongly influence droplet-droplet and droplet–membra
Wall-resolved large eddy simulations (LES) are performed to investigate turbulent heat transfer in a rough pipe over a range of Prandtl () numbers. The rough surface is generated using a controlled numerical procedure that allows independent specification of roughness correlation length, amplitude, and skewness; a statistically Gaussian height distribution is considered as a baseline case. The r
Matrix cooling is an internal cooling concept for gas turbine blades that combines structural reinforcement with enhanced heat transfer through a rib-crossing lattice geometry. The repeated flow redirection generates strong shear layers, impingement, and vortical structures that significantly influence turbulent transport and heat transfer. This study presents a numerical investigation of turbulen
This study models Additive Manufacturing (AM) roughness using a statistical distribution of spheres and performs high-fidelity simulations at a bulk Reynolds number of 12,000 and a large range of Prandtl numbers to evaluate heat transfer on a rough pipe. Statistical measures were deployed to highlight a clear correlation between roughness features and heat transfer. To directly connect surface top
Growth of the intermetallic compound (IMC) Cu6Sn5 in Sn/Cu coatings is a major source of stress evolution and is closely linked to the reliability of electroplated Sn layers, including their susceptibility to whisker formation. Here, we investigate how Sn grain morphology and grain boundary (GB) transport control stress development during diffusion-controlled Cu6Sn5 growth. A thermodynamically con
Railway traffic is experiencing notable growth but also faces competition from other modes of transport with considerable technological developments. One way to improve rail transport is by optimizing train operations at both the management and train levels. At the train level, the implementation of Automatic Train Operation (ATO) can be employed. This ATO facilitates efficient operation and serve
The growing need for intelligent transportation systems (ITS) to provide advanced train-related information has driven the development of train delay prediction models. The study used a case study in Sweden to illustrate how various prediction models can be evaluated under various aspects and dimensions in order to determine their effectiveness in practical implementation. The outputs of three pre
This thesis examines the taxation of employment income derived from cross-border work in light of new ways of working. Its central focus is Article 15 of the OECD Model Tax Convention, which allocates taxing rights over income from employment primarily on the basis of where the work is physically performed. The thesis asks whether this framework remains suitable in a labour market increasingly cha
Background: Heterogeneous treatment response, characterized by simultaneous regression of some lesions and progression of others within the same patient, is increasingly recognized in metastatic breast cancer (mBC) and may reflect biological heterogeneity. However, this response pattern is not captured by current response assessment frameworks. We aimed to determine the prevalence of heterogeneous
Bounding the correlations predicted by quantum theory is an important challenge in quantum information science. Today’s leading approach is semidefinite programming relaxations, but existing methods still cannot account for many relevant types of constraints. Here, we propose a general semidefinite relaxation methodology that can incorporate a breadth of constraints needed in various quantum corre
Background Accurate response assessment during systemic therapy of metastatic breast cancer (mBC) is essential to guide treatment decisions. We aimed to compare the applicability of RECIST 1.1 (CT) and PERCIST (FDG-PET) for response evaluation in mBC within a contemporary real-world setting. Methods In this retrospective cohort study, mBC patients undergoing systemic therapy between 2017 and 2025
Correlations that do not admit a deterministic explanation are a central feature of quantum theory and a key resource for quantum information processing. Identifying and certifying such correlations, however, remains a fundamental challenge. In this work, we advance on this problem by considering deterministic correlations in the prepare-and-measure scenario consistent with a wide range of communi
We establish a connection between Hardy's paradox and nonlocality sharing in sequential bipartite scenarios, where each subsystem is measured in turn by a chain of observers. We show that any correlations exhibiting a Hardy paradox in the two-input two-output scenario enable sequential violations of the CHSH inequality between arbitrarily many pairs of observers, using only projective measurements
Bimetallic CuZn (brass) nanoparticles are key materials in catalytic applications, yet access to the full compositional range remains challenging using conventional wet chemical synthesis. In this study, we demonstrate the physical synthesis of CuZn nanoparticles across a broad compositional range using spark ablation of alloyed feedstocks (Cu25Zn75, Cu50Zn50, Cu75Zn25). In spark ablation, the nan
This study deals with the stratospheric aerosol during the 17 years of lidar measurements with CALIOP aboard the CALIPSO satellite. To obtain extinction from the backscattering measurements, we estimated the lidar ratios of the main aerosol injections into the stratosphere. The stratospheric background is estimated by making a subdivision of the stratosphere into nine parts, spanned by three latit
