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Highly Sensitive Hydrogen Peroxide Biosensor Based on Tobacco Peroxidase Immobilized on p-Phenylenediamine Diazonium Cation Grafted Carbon Nanotubes : Preventing Fenton-like Inactivation at Negative Potential

Herein, we present a novel electrode platform for H2O2 detection based on the immobilization of recombinant Tobacco Peroxidase (r-TOP) onto graphite electrodes (G) modified with p-phenylenediamine (p-PD) diazonium cation grafted multi-walled carbon nanotubes (MWCNTs). The employment of both p-phenylenediamine moieties and covalent cross-linking by using glutaraldehyde allowed us to enhance the sen

Gambling and self-reported changes in gambling during COVID-19 in web survey respondents in Denmark

Problem gambling is among the public health hazards which may increase due to the COVID-19 pandemic and its consequences on society. Results from a few countries have hitherto been diverse with respect to gambling during the pandemic. The present study aimed to study gambling behaviors during COVID-19 in Denmark, with the same methodology as previously used in Sweden, and also to provide a compari

Infiltration of NK and plasma cells is associated with a distinct immune subset in non-small cell lung cancer

Immune cells of the tumor microenvironment are central but erratic targets for immunotherapy. The aim of this study was to characterize novel patterns of immune cell infiltration in non-small cell lung cancer (NSCLC) in relation to its molecular and clinicopathologic characteristics. Lymphocytes (CD3+, CD4+, CD8+, CD20+, FOXP3+, CD45RO+), macrophages (CD163+), plasma cells (CD138+), NK cells (NKp4

Incidence and prevalence of systemic sclerosis globally : A comprehensive systematic review and meta-analysis

Objectives: We aimed to conduct a systematic review and meta-analysis on the incidence and prevalence of SSc covering the entire literature. Methods: This study followed the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement of 2009. We conducted a systematic search in MEDLINE, Web of Science and Embase to identify articles reporting incide

Preparedness for family caregiving prior to allogeneic hematopoietic stem cell transplantation

Objective Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment associated with high morbidity and mortality. It is often necessary for family caregivers to become highly involved in the care, especially when patients return home after a long period of inpatient care. Family caregivers' preparedness for the tasks and demands of the caregiving role prior to allo-HSC

Destination net-zero : what does the international energy agency roadmap mean for tourism?

The tourism sector has recommitted itself to be ‘climate neutral’ by 2050 through its 2021 Glasgow Declaration: A Commitment to a Decade of Tourism Climate Action. The declared ambition is consistent with the Paris Climate Agreement and net-zero emission targets; however, lacks specific actions by which such a transition might be achieved. The highly influential International Energy Agency (IEA) h

New Lactiplantibacillus plantarum and Lacticaseibacillus rhamnosus strains : well tolerated and improve infant microbiota

Background: Different microorganisms from the environment will begin to colonise the infant during and immediately after the delivery. It could be advantageous to influence the microbiome early on by giving infants probiotic bacteria. The aim of the study was to investigate the tolerance of two probiotic lactobacilli in infants. The effect on the microbiota was also followed. Methods: Thirty-six h

Rugged relief and climate promote isolation and divergence between two neotropical cold-associated birds

The role of historical factors in establishing patterns of diversity in tropical mountains is of interest to understand the buildup of megadiverse biotas. In these regions, the historical processes of range fragmentation and contraction followed by dispersal are thought to be mediated by the interplay between rugged relief (complex topography) and climate fluctuations and likely explain most of th

Translation and validation of Assessment of Work Performance (AWP) into the Icelandic language and culture

BACKGROUND:Evidence-based services in vocational rehabilitation call for valid and reliable assessments of work performance for intervention planning and safe return to work for individuals with illness or injuries. Assessments that are easy to use, culturally adapted, and in a language professionals and clients understand is important for their utility. Translation and adaption of assessments to

Feature selection in jump models

Jump models switch infrequently between states to fit a sequence of data while taking the ordering of the data into account We propose a new framework for joint feature selection, parameter and state-sequence estimation in jump models. Feature selection is necessary in high-dimensional settings where the number of features is large compared to the number of observations and the underlying states d

The trelleborg constructors

This text builds on a manuscript written for a lecture at the Trelleborg Museum in Scania. At the museum one can read that Harald Bluetooth built the ring fortress, just like all the other Trelleborg forts, but is this so? This article looks at the datings, finds and surroundings of the East Danish trelleborg forts and presents another interpretation. A strong aristocracy with an interest in trade

Tax avoidance and state ownership : The case of Sweden

We propose a simple theoretical model for how a company with both private and state shareholders decides on its optimal tax policy. The model predicts that even in the absence of state shareholding, a company will not always pick a tax policy that minimizes taxes. Conversely, majority state ownership will generally not result in zero tax avoidance. Using panel regressions on the entire population