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Background: For decades, early allogeneic stem cell transplantation (HSCT) has been used to slow neurological decline in metachromatic leukodystrophy (MLD). There is lack of consensus regarding who may benefit, and guidelines are lacking. Clinical practice relies on limited literature and expert opinions. The European Reference Network for Rare Neurological Diseases (ERN-RND) and the MLD initiativ

The Cretaceous - Paleogene boundary (K-Pg, 66 Ma) was a time interval with dramatic changes in the Earth’s climate and the ocean environment. It was characterized by severe disruptions of marine biogeochemical cycles due to a meteorite impact during a time of active volcanism. The extinction of calcifiers, among others, influenced biogeochemical cycles and changed the conditions for carbonate depo

Creosote has been used in Sweden as a wood preservative in buildings since the 19th century. These buildings can function as workplaces, homes, and cultural buildings to which the public has access. Creosote contains polycyclic aromatic hydrocarbons (PAH) which are well known carcinogens. To understand exposure and risks in an indoor environment, it is important to determine air levels of parent P

Rosenberg, Tiina, Sandra D'Urso & Anna Renée Winget, eds. 2021. The Palgrave Handbook of Queer and Trans Feminisms in Contemporary Performance. Cham: Palgrave Macmillan. (541 pages)

The Swedish far-right party, the Sweden Democrats (SD), came to power in 2022 and is currently the second-largest party in the Swedish Parliament, the Riksdag. While it has been propagandizing an anti-migrant discourse, another newly founded party has been producing a counter-discourse. The newly created Nyans party claims to represent migrants and minorities in Sweden. However, its discourse uses

Mixed-phase clouds contain both supercooled cloud liquid and ice crystals. In principle, precipitation may be initiated either by the liquid phase or by the ice phase. Ice crystals may grow by vapor diffusion to become snow ("ice crystal process"), forming "cold"precipitation. Equally, cloud droplets, when large enough, coalesce to form "warm"precipitation by the "warm rain process."Warm rain coul

The Cantril Ladder is among the most widely administered subjective well-being measures; every year, it is collected in 140+ countries in the Gallup World Poll and reported in the World Happiness Report. The measure asks respondents to evaluate their lives on a ladder from worst (bottom) to best (top). Prior work found Cantril Ladder scores sensitive to social comparison and to reflect one’s relat

The mild, fast and green removal of hexavalent chromium (Cr(VI)) from wastewater has already attracted extensive attention due to the severe acute toxicity and carcinogenicity of Cr(VI). At present work, Bi2S3/Bi2MoO6 S-scheme heterojunctions were constructed by facile solvothermal assembly and in situ anion exchange methods for visible light-driven efficient photocatalytic removal of Cr(VI). The

For almost a century, the knock-resisting ability of a spark ignition fuel has been quantified with the RON and MON indications, conforming to the corresponding ASTM-D2699 and D2700 methods, respectively. These testing methods rely on specific pressure pickup technology that acts like a low-pass signal filter, thereby cutting off high frequency cylinder pressure information. Within a second-genera

Current precision cancer medicine is dependent on the analyses of a plethora of clinically relevant genomic aberrations. During the last decade, next-generation sequencing (NGS) has gradually replaced most other methods for precision cancer diagnostics, spanning from targeted tumor-informed assays and gene panel sequencing to global whole-genome and whole-transcriptome sequencing analyses. The shi

Pollen-based quantitative vegetation reconstructions using multiple sedimentary basins from the same area, along with their quantified relevant pollen source areas, are a powerful means to study how long-term human impact has affected vegetation and shaped the currently protected heritage landscapes at different spatial scales. Our study presents the outcome of a palynological investigation in Kar

In this narrative review, we survey recent empirical evaluations of AI-based language assessments and present a case for the technology of large language models to be poised for changing standardized psychological assessment. Artificial intelligence has been undergoing a purported “paradigm shift” initiated by new machine learning models, large language models (e.g., BERT, LAMMA, and that behind C

BackgroundSocial concerns about unintentional HIV status disclosure and HIV-related stigma are barriers to pregnant women’s access to prevention of mother-to-child transmission of HIV (PMTCT) care. There is limited quantitative evidence of women’s social and emotional barriers to PMTCT care and HIV disclosure. We aimed to investigate how social concerns related to participation in PMTCT care are aBackground: Social concerns about unintentional HIV status disclosure and HIV-related stigma are barriers to pregnant women's access to prevention of mother-to-child transmission of HIV (PMTCT) care. There is limited quantitative evidence of women's social and emotional barriers to PMTCT care and HIV disclosure. We aimed to investigate how social concerns related to participation in PMTCT care are

Exploring the future hydroclimatic conditions of source region of Yangtze River (SRYaR), an alpine affected by climate change significantly, is essential for basin water resources management and development ss global climate change intensifies and the process of climate warming and humidification in Northwest China. This study proposed a practical framework for assessing water resource response to

Mother-to-child transmission of HIV remains a significant concern in Africa despite earlier progress. Early infant diagnosis (EID) of HIV is crucial to reduce mortality among infected infants through early treatment initiation. However, a large proportion of HIV-exposed infants are still not tested in Kenya. Our objective was to investigate whether weekly interactive text-messages improved preventMother-to-child transmission of HIV remains a significant concern in Africa despite earlier progress. Early infant diagnosis (EID) of HIV is crucial to reduce mortality among infected infants through early treatment initiation. However, a large proportion of HIV-exposed infants are still not tested in Kenya. Our objective was to investigate whether weekly interactive text-messages improved prevent

Retention in prevention of mother-to-child transmission (PMTCT) care is critical to prevent vertical HIV transmission and reduce morbidity and mortality of mother-infant pairs. We investigated whether weekly, interactive text-messaging improved 18-month postpartum retention in PMTCT care. This randomised, two-armed, parallel trial was conducted at six PMTCT clinics in western Kenya. Pregnant womenRetention in prevention of mother-to-child transmission (PMTCT) care is critical to prevent vertical HIV transmission and reduce morbidity and mortality of mother-infant pairs. We investigated whether weekly, interactive text-messaging improved 18-month postpartum retention in PMTCT care. This randomised, two-armed, parallel trial was conducted at six PMTCT clinics in western Kenya. Pregnant women

BackgroundTo improve future mobile health (mHealth) interventions in resource-limited settings, knowledge of participants’ adherence to interactive interventions is needed, but previous studies are limited. We aimed to investigate how women in prevention of mother-to-child transmission of HIV (PMTCT) care in Kenya used, adhered to, and evaluated an interactive text-messaging intervention.MethodsWeBackground: To improve future mobile health (mHealth) interventions in resource-limited settings, knowledge of participants’ adherence to interactive interventions is needed, but previous studies are limited. We aimed to investigate how women in prevention of mother-to-child transmission of HIV (PMTCT) care in Kenya used, adhered to, and evaluated an interactive text-messaging intervention. Method

This article addresses physics teachers’ views about physics teaching in upper-secondary school. Their views have been investigated nationwide through a web-based questionnaire. The questionnaire has been developed based on several published instruments and is part of an ongoing project on the role of mathematics in physics teaching at upper-secondary school. The selected part of the results from