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Novel antibiotics, such as antimicrobial peptides (AMPs), have recently attended more and more attraction. In this work, dispersed cubic liquid crystalline gel (cubosomes) was used as drug delivery vehicles for three AMPs (AP114, DPK-060 and LL-37). Association of peptides onto cubosomes was studied at two cubosome/peptide ratios using high performance liquid chromatography, ζ-potential and circul

Purpose. Congenital heart disease (CHD) is reported to be associated with Hirschsprung disease (HD). The aim was to evaluate any differences between children with HD with and without CHD, respectively, with regard to patient characteristics, medical care, and patient reported bowel function. Method. This is a retrospective chart study and a cross-sectional long-term follow-up of patients older tha

This chapter reflects on the relationship between various stakeholders in the health-care industry and intelligent medical systems. It takes into consideration the potential impact that intelligent systems have on health care. The aim of the chapter is to emphasise a set of decisive factors for the successful deployment of intelligent systems in health care including the individual needs of patien

Analytical relations to describe experimentally measured traction-separation laws are often expressed in dimensionless quantities. The traction and the separation are commonly normalized using the cohesive strength and a length measure, respectively. The ratio between the fracture energy and the cohesive strength is often used as a length measure. An alternative length measure is the ratio between

Climate change and water extraction may result in increased exposition of the biota to ultraviolet-B radiation (UVB) in high-altitude Andean lakes. Although exposition to lethal doses in these lakes is unlikely, sub-lethal UVB doses may have strong impacts in key compartments such as zooplankton. Here, we aimed at determining the effect of sub-lethal UVB doses on filtration rates of two cladoceran

The figure-ground segmentation of humans in images captured in natural environments is an outstanding open problem due to the presence of complex backgrounds, articulation, varying body proportions, partial views and viewpoint changes. In this work we propose classspecific segmentation models that leverage parametric max-flow image segmentation and a large dataset of human shapes. Our contribution

Skeletal muscle has high energy requirement and alterations in metabolism are associated with pathological conditions causing muscle wasting and impaired regeneration. Congenital muscular dystrophy type 1A (MDC1A) is a severe muscle disorder caused by mutations in the LAMA2 gene. Leigh syndrome (LS) is a neurometabolic disease caused by mutations in genes related to mitochondrial function. Skeleta