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Protein-specific and shared genetic pathways influence the spread of amyloid-β and tau pathology. Hence, distinct gene expression profiles may induce regional vulnerability of the human cortex to the specific proteinopathies of Alzheimer’s disease.
Gravkistor från domkyrkoområdet till tiden omkring 970 visar att Harald Blåtand var stadens grundare. Med georadar har en fyrsidig anöäggning, troligen ett kloster från 1040-talet, påvisats under den nuvarande domkyrkan. Stenen till byggnaden kom från Helsingborgs- och Ystadstrakten.
A computer simulated microworld was used to study risk management in a critical infrastructure context. 36 students assumed the role of an electric distribution company Chief Executive Officer (CEO) making decision on how to spend resources between investments in risk reduction and other investments. We studied the effect of differences in terms of the incentives to invest in risk reduction and th
Αν και η αρχαία ελληνική αποτελούσε βασικό μάθημα στο Πανεπιστήμιο Lund από την αρχή της λειτουργίας του, η διδασκαλία της Νέας Ελληνικής ξεκίνησε το 1957 υπό την επίδραση του αυξανόμενου ενδιαφέροντος για τη νεοελληνική λογοτεχνία και της ανάγκης εκπαίδευσης των Σουηδών αρχαιολόγων με αντικείμενο έρευνας την Ελλάδα. Το Τμήμα Νεοελληνικών Σπουδών του Πανεπιστημίου Lund, έχοντας πλέον αυτονομηθεί α
Glial cell-line derived neurotrophic factor (GDNF) is a promising therapeutic molecule to treat Parkinson’s disease. Despite an excellent profile in experimental settings, clinical trials testing GDNF have failed. One of the theories to explain these negative outcomes is that the clinical trials were done in late-stage patients that have advanced nigrostriatal degeneration and may therefore not re
Omkring 1080 påbörjades den ännu stående kyrkan. Arbetet utfördes sannolikt till stor den av slavarbetskraft, stenen kom från Hallaröd/Munkarpområdet och kördes längs en väg, vars spår ännu syns i landskapet. En stor del av artikeln behandlar slavar, slavhandel och slavsamhälets upphörande den därmed sammanhängande kolonisationen av Skånes allmänningsskogar
Allelopathy in bryophytes shapes ecosystems by influencing the species composition of both vascular plants and other bryophytes. Several allelopathically active chemicals in bryophytes have been discovered since the latter half of the 20th century and laboratory studies have showed their inhibiting impact on germination, growth and establishment of surrounding plants. However, other studies failed
Background: Total heart volume (THV) within the pericardium is not constant throughout the cardiac cycle and THV would intuitively be lowest at end systole. We have, however, observed a phase shift between ventricular outflow and atrial inflow which causes the minimum THV to occur before end systole. The aims were to explain the mechanism of the late-systolic net inflow to the heart and determine
Background: The aim of this prospective cohort study was to determine the feasibility of incorporating blue light flexible cystoscopy (BLFC) and biopsy/fulguration into routine outpatient follow-up of non-muscle invasive bladder cancer patients. Methods: The study included patients with non-muscle-invasive bladder cancer (NMIBC) who were scheduled for routine follow-up. Hexaminolevulinate was inst
[Preliminary results from bryophyte spore capsule records in the county of Skåne, southernmost Sweden] Occurrences of sporophytes are recorded by inventorers within the bryophyte flora project for Skåne. Here we present commented distribution maps with sporophyte presence/absence indicated for Calliergonella cuspidata, Dicranum scoparium, Encalypta streptocarpa, Homalothecium sericeum, Hylocomium
A rigid mineral-based deposit, termed ultra-high temperature (UHT) fouling, is formed on heat exchanger surfaces during milk processing at 140 °C. The removal of this type of fouling is for the first time assessed using a laser triangulation sensor and a camera, to measure changes in the thickness and to visualize structural changes in the fouling in situ. The process was monitored during both the
Objective: Glycoproteomics is an emerging subfield of proteomics. Tumor-specific variations in protein glycosylation might be potential targets for the development of new cancer diagnostics. Here, we performed high-throughput screening and targeted verification of glycome alterations in serum samples from patients with pancreatic cancer and the precancerous lesion intraductal papillary mucinous ne
Objective: Studies of the etiology of intestinal metaplasia (IM) at a normal appearing gastroesophageal junction (GEJ) are conflicting as associations with both H. Pylori (HP) infection and gastroesophageal reflux has been reported. The aim of this study was to investigate whether IM at the GEJ is associated with gastroesophageal reflux or HP infection. Material and methods: Fifty asymptomatic vol
Performing risk assessments for hierarchical, multi-functional systems, such as a municipality, is an activity that requires input from a multitude of actors. In such systems risk assessments can be performed at many system levels and support different types of decisions. For issues that are constrained to a specific sub-system, such as a municipal department, decisions can be preferably taken at
This paper presents the case study of a newly constructed 1600 m2 kindergarten building in Oslo, Norway. The building has been designed within the framework of the Norwegian Research Council Project LowEx, which aims at engineering solutions to achieve a seasonal coefficient of performance (SCOP) of 6–10 for heating, a seasonal energy efficiency ratio (SEER) of 80–100 for cooling, and an 80% reduc
Critical technical infrastructures constitute the backbone of society by providing essential services to vital societal functions and the community at large, hence it is of essence that these are resilient. Critical infrastructures, e.g. power systems, telecommunication systems and railway systems, are designed and operated based on different philosophies of where to put the resilience emphasis, r
In recent years, cognitive robots have started to find their way into manufacturing halls. However, the full potential of these robots can only be exploited through (a) an integration of the robots with the Manufacturing Execution System (MES), (b) a new and simpler way of programming based on robot skills, automated task planning, and knowledge modeling, and (c) enabling the robots to function in
Objectives. Guidelines of the European Society of Cardiology (ESC) recommend that ferritin and transferrin saturation should be tested in chronic heart failure (HF) and state that iron treatment with ferric carboxymaltose should be considered in HF patients with iron deficiency to alleviate symptoms and improve exercise tolerance and quality of life. This study evaluates the cost effectiveness of
Tetrahydroxystilbene glucoside (TSG) is the main water-soluble component in Polygonum multiflorum Thunb, and it has many cardioprotective effects. Although TSG is able to relax blood vessels, its relaxation of rat superior mesenteric arteries and the underlying mechanism of this process are not clearly understood. The aim of the present study was to use in vivo and in vitro models to investigate t
The aim is to prospectively investigate both the “cohesion” and “network” perspectives of social capital in relation to total, cardiovascular (CVD), cancer and all other causes mortality. The 2008 public health survey in Scania was a postal questionnaire with three letters of reminder, and it was answered in the Autumn by 28,198 respondents (55% participation) aged 18–80 from a stratified random s
