Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural stem cells and have a supportive effect on human embryonic stem cell growth. Here, we analyzed expression of PEDF in the murine hematopoietic stem cell (HSC) compartments and found that PEDF is highly expressed in primary long-term HSCs. Theref

One of the promising devices to obtain electrical and thermal energy with considerable high efficiency is the solid oxide fuel cell (SOFC). The electrical energy is the result of the electrochemical reactions that occur inside the fuel cell (FC) when the reactant gases reach the so-called three-phase boundary (TPB). The nonhomogeneous and anisotropic characteristics of the layer between the gas ch

Asthma is a common airway inflammatory disease, associated with a variable degree of airway obstruction. It is a heterogeneous condition with large variations in severity and clinical presentation. Moreover, disease activity can vary from time to time. Taken together, these factors make the diagnosis, monitoring and treatment of asthma challenging. Peripheral airway inflammation has been shown to

The planetary changes associated with the Anthropocene, including climate change and extinction of species, pose severe threats to civilization, humanity, and the natural world as we know it. They also pose special challenges to the human imagination. To meet these challenges, climate change communicators use narratives. Nonfiction books intended for a general audience employ two radically differeThe planetary changes associated with the Anthropocene, including climate change and extinction of species, pose severe threats to civilization, humanity, and the natural world as we know it. They also pose special challenges to the human imagination. To meet these challenges, climate change communicators use narratives. Nonfiction books intended for a general audience employ two radically differe

Deciphering the assembly history of the Milky Way is a formidable task, which becomes possible only if one can produce high-resolution chrono-chemo-kinematical maps of the Galaxy. Data from large-scale astrometric and spectroscopic surveys will soon provide us with a well-defined view of the current chemo-kinematical structure of the Milky Way, but it will only enable a blurred view on the tempora

Cerebral circulation is regulated by two principal systems: autonomic and sensory nerves from cranial ganglia and intrinsic innervation of the cerebral microcirculation. The sympathetic innervation originates from the superior cervical ganglion and stores noradrenaline and neuropeptide Y. It has a role in the extreme limits of the autoregulation. The parasympathetic innervation of the brain circul

Recension av antologin Känslornas revolution

It is vital to extend the service life of existing bridges as far as possible as a means for improved sustainability leading to reduced economic cost and resource consumption. This requirement is especially valid for bridges which are critical components of highly vulnerable infrastructure systems. Achieving this aim requires enhanced methods involving various actions and methods influencing diffe

This paper presents a study where resistivity and integral chargeability three-dimensional (3D) models, representing a volume in the vicinity of a rock quarry is compared to a quasi-3D characterization of rock mass volume. By repeating geological mapping, i.e. with unmanned aerial vehicles, ground based high resolution photography and sampling, as the quarry operation reaches further into the rock