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OBJECTIVE: To analyze the extent of tumor necrosis factor-alpha (TNFalpha) and TNFbeta gene polymorphism in patients with AD and to relate it to intrathecal levels of these cytokines. METHODS: Analyses of TNFalpha and TNFbeta gene polymorphism were performed using PCR in 52 patients with AD and in 25 control subjects, and the levels of corresponding cytokines were analyzed using ELISA. RESULTS: Pa
Popular Abstract in Swedish Avhandlingen innehåller sju artiklar. Här presenteras ett nytt koncept för att beskriva hur fukt transporteras i porösa material. Detta bygger på införandet av en äkta flödespotential, Kirchhoff's potential. Betraktelsesättet täcker hela processen från mätning av materialdata till numerisk beräkning av fukttransport. Modeller för beräkning av fuktinträngning vid stegäThe work presented in this thesis is focused on the development of the new concept to describe isothermal moisture transport using Kirchhoff potentials. The first four papers deal with moisture transport in porous media using Kirchhoff potentials. The last three papers deal with wood. Here the theory is extended to the case of anisotropic moisture transport. The seven papers have the following con
Polymer gel electrolyte membranes were prepared by first casting films of poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP), lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) salt, and poly(ethylene glycol) (PEG) monomethacrylate and dimethacrylate macromonomers. Polymerization of the macromonomers initiated by UV-irradiation then generated solid films having phase-separated morphologi
Objective To investigate the cross-sectional relationship between subjective quality of life and sociodemographic clinical and social factors over three points of assessment during a 6-year follow-up, and to investigate longitudinal predictors of subjective quality of life. Method We investigated a sample of people with severe mental illness (n = 92), mainly with a psychosis diagnosis, at baseline
Girls take up smoking at least as frequently as boys. Few studies have focused on gender differences in the impact of adolescent smoking. We evaluated the sex-specific effect of adolescent smoking on respiratory symptoms and lung function. All students in junior high and high schools in Nord-Trondelag County Norway, 1995-97, were invited to participate in a cross-sectional study. Information on sm
Metabotropic glutamate receptor type 5 (mGluR5) modulates dopamine and glutamate neurotransmission at central synapses. In this study, we addressed the role of mGluR5 in L-DOPA-induced dyskinesia, a movement disorder that is due to abnormal activation of both dopamine and glutamate receptors in the basal ganglia. A selective and potent mGluR5 antagonist, 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] pyri
The photodissociation dynamics of CH2ICH2I, CF2ICF2I, and CF2BrCF2I have been studied in solution after excitation at 266 nm. Formation of I-2 is apparent within tens of picoseconds in solutions of CH2ICH2I and CF2ICF2I in acetonitrile. but not from CF2BrCF2I, More I-2 is formed from CH2ICH2I rather than from CF2-ICF2I, as expected if the 12 formation is a result of secondary dissociation of the h
The aim of the study was to evaluate the influence of a-ketoglutarate (AKG), at pH 2 or 5, combined with vitamin B-6 (AKG 2B, AKG 5B) or C (AKG 2C, AKG 5C), on the performance and haemoglobin and amino acid levels in growing rats. Eighty rats were divided into 5 treatment groups and stayed on trial for 9 d (n=16) or 18 d (n=10). No significant differences in average daily gain (ADG), average daily
During the last decades, there has been concern that the environmental contaminants, such as POPs, may contribute to sex ratio changes in offspring of exposed populations. Accidental exposure to TCDD has been shown to be associated with fewer sons in men who were exposed in adolescence or earlier in life. However, it is not known whether POPs could change the proportion of X- and Y-sperm. A variet
Sulfate adsorption was implemented in the dynamic, multi-layer soil chemistry model SAFE. The process is modeled by an isotherm in which sulfate adsorption is considered to be fully reversible and dependent on sulfate concentration as well as pH in soil solution. The isotherm was parameterized by a site-specific series of simple batch experiments at different pH (3.8–5.0) and sulfate concentration
The E-GIS project partnership comprised 10 partners (universities, organisations and private bodies) from 6 European countries; Bulgaria, Lithuania, The Netherlands, Norway, Portugal and Sweden. The E-GIS project was initiated in order to: • Establish competent nettworks between universities and private bodies for cooperation on an European level within the GIS area – both for this project and fo
