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Background: Breast cancer diagnoses are limited in low- and middle-income settings due to lack of medical resources. In these settings, point-of-care ultrasound (POCUS) combined with artificial intelligence (AI)-based interpretation could be a suitable approach. Purpose: To compare the performance of an AI-based breast cancer classification algorithm with radiologists and assess whether POCUS perf
Background Screening with digital breast tomosynthesis (DBT) detects more cancers than with digital mammography (DM), but has small effect, if any, on interval cancer incidence. Methods Data were pooled from two randomized trials within the MAITA Consortium, including 100743 women (664 cancers) screened at baseline and 82938 women (550 cancers) followed for cumulative incidence at subsequent round
Abstract - Instructional Course Structure • Chair: Jenny Carroll. • Speakers: Lisbeth Nilsson, Kirsty Taylor and Iwona Orlowska. Objectives • To share the process and outcomes of establishing an early mobility playgroup for children aged 6 months - 3 years who have complex neuro-disability. • To explore how the ‘Driving to Learn’ approach and the ALP-tool (Assessment of Learning Powered mobility
Purpose: Children gain increased health and well-being by participating in physical activity (PA) and exercise. Globally, only 19% of children meet the World Health Organisation recommendations on PA and the rates are even lower among children with disabilities. Children with disabilities are often dependent on assistive exercise products (AEP) to be able to perform PA and exercise. The aim was
Cancer cells display marked heterogeneity in size and morphology, traits long recognized in pathology as indicators of pleomorphism and poor prognosis. Yet, the functional significance and phenotypic consequences of these morphological variations within a single cancer cell population remain poorly understood. Here, we employed a deterministic lateral displacement (DLD) microfluidic device with a
A novel phylogenetic hypothesis for the subfamilies Dyopsinae and Thiacidinae is presented. For the first time, the type genus and species of Thiacidinae, Thiacidas postica Walker, is sequenced and analysed within an expanded dataset that includes a diverse array of representative Noctuidae. Utilizing a combination of phylogenomic data and traditional phylogenetic analyses based on legacy (Sanger)
To estimate prevalence and associated factors of comorbid fibromyalgia in axial spondyloarthritis (axSpA), and to explore discriminative capacity (for discerning fibromyalgia) of algometry-assessed pain sensitivity measures. AxSpA patients from the population-based SPARTAKUS cohort evaluated for fibromyalgia (1990 ACR criteria) were included (n = 243; r-axSpA/nr-axSpA = 165/78). Factors associated
In 2024–2025, the Cystic Fibrosis Foundation (US) and Cystic Fibrosis Trust (UK) hosted an International CFRD Consortium round-table webinar series for basic science, translational, and clinical researchers with the goal of sharpening mechanistic understanding of CFRD pathogenesis and prioritizing therapeutic development. This review summarizes the research priorities identified in the Internation
Snow flies ( Chionea ) are wingless crane flies uniquely adapted to extreme cold environments. Adults remain active throughout winter and move rapidly across the snow, even at temperatures below freezing. To investigate the molecular adaptations that make this possible, we sequenced and annotated the genome of Chionea alexandriana and compared it with related species and with the cold-adapted midg
Neurodegenerative diseases have traditionally been defined in vivo based on clinical symptoms. However, the development of biomarkers has enabled a shift towards in vivo biological definitions. There is now a need to characterize memory clinic populations using multi-dimensional biomarker information. Here, we employed a data-driven approach to develop a biological framework for categorizing indiv
The study of clines, or geographical variations of a given trait, can help understand how the interactions of genetics and local environments determine phenotypic diversity. The marine snail Littorina saxatilis (Olivi, 1792) exhibits a gradual change in the relative frequencies of shell color morphs across populations in the estuary system of the Rias Baixas (Galicia, NW Iberian Peninsula). A cons
This chapter analyzes how Lundin Oil responded publicly and legally to accusations of complicity in human rights violations connected to its operations in southern Sudan. Since receiving a concession in Block 5A in 1997, the company has faced persistent accusations from civil society organizations. In 2010, the Swedish Prosecution Authority launched a preliminary investigation, and in 2023, two fo
The JPL rover Perseverance's investigations of Jezero crater's floor reveal that the ultramafic Séítah formation and the overlying mafic Máaz formation are deformed into a broad, low-amplitude structural dome. Mastcam-Z stereo images processed into digital outcrop models, together with RIMFAX ground-penetrating radar profiles, were used to reconstruct the three-dimensional stratal geometry of both
Background: Obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity; however, its relationship with subclinical coronary atherosclerosis detected incidentally on routine chest computed tomography (CT) remains incompletely defined. We aimed to evaluate the association between questionnaire-based OSA risk and moderate-to-severe coronary artery calcification (CAC) in patie
Corporate misconduct is a persistent feature of contemporary organizational life, yet corporations rarely acknowledge wrongdoing when confronted with allegations of harm. Instead, they rely on discursive strategies that protect legitimacy, organizational identity, and moral credibility. This chapter examines how corporations employ techniques of neutralization to defend themselves against accusati
Persistent circulating tumor DNA (ctDNA) during neoadjuvant treatment (NAT) of early breast cancer (EBC) indicates high-risk disease. Similarly, detection of ctDNA post-resection indicates molecular residual disease (MRD) and impending relapse. For ctDNA to be integrated into EBC management, accessible and scalable diagnostics are required. Here we apply an ultrasensitive, personalized tumor-infor
Minnesord över Eva Österbergs gärning som historiker, hennes forskningsinsatser och värdefulla arbete som handledare.
