Induced pluripotent stem cells (iPSCs) generated from somatic cells of patients can be used to model different human diseases. They may also serve as sources of transplantable cells that can be used in novel cell therapies. Here, we analyzed neuronal properties of an iPSC line derived from a patient with a juvenile form of Huntington's disease (HD) carrying 72 CAG repeats (HD-iPSC). Although its i

Many patients experience postoperative nausea and vomiting (PONV). Preoperative treatment with carbohydrate solutions seems to improve the course after different types of surgery. This study was undertaken to investigate the potential value of different models for preoperative hydration/nutrition, in addition to our ERAS (enhanced recovery after surgery) protocol.

Background: The presence of echolucent carotid plaques as defined by low ultrasound grey-scale median (GSM) is associated with a higher risk of stroke and myocardial infarction. Betablockers have shown possible anti-atherosclerotic effects. The aim of the present study was to determine if there is an association between carotid plaque GSM and treatment with betablockers. Methods: The GSM of the ca

This paper analyses household behaviour as response to changes in waste management systems. The paper discusses the results of a case study from Vellinge municipality (Sweden), where the introduction of separate food waste collection is thought to have a role in reducing the total amount of household waste and improving the sorting of packaging waste. The study relies on data from official waste s

OBJECTIVE: The aim was to compare skin assessment by palpation and by high-frequency ultrasound in patients with SSc with disease duration

Background: Serum creatinine-based estimates of GFR may be inaccurate in the elderly and there is need for improvement. Serum Cystatin C, not being influenced by muscle volume, may be more accurate. Material and methods: GFR was measured with plasma clearance of iohexol in 50 elderly persons aged >70 years. Blood tests were drawn for analysis of creatinine, albumin and urea. Cystatin C was analyse

Model-based process design is increasingly popular when designing pharmaceutical purification processes. The effect of uncertainties in concentration measurements on the estimation of model parameters is analyzed for two cases of non-isocratic adsorption chromatography. A model, calibrated to experiments, is used to generate data by adding a Monte Carlo sampled error in the inlet concentrations. N

The MUSA (Morphological Uterus Sonographic Assessment) statement is a consensus statement on terms, definitions and measurements that may be used to describe and report the sonographic features of the myometrium using gray-scale sonography, color/power Doppler and three-dimensional ultrasound imaging. The terms and definitions described may form the basis for prospective studies to predict the ris

Popular Abstract in Swedish En värld av mikrober Vi lever i en värld full av olika bakterier och svampar, så kallade mikrober. Med tanke på artrikedomen och mängden av infektiösa mikrober vi dagligen kommer i kontakt med kan det nästan tyckas som ett smärre mirakel att vi trots allt är så friska som vi är. Detta är dock nästan helt och hållet vårt medfödda immunförsvars förtjänst. Immunförsvaret Abstract The epidermis is one of our primary interfaces towards the external milieu. Following injury, the physical barrier function of the skin is destroyed and the epidermis is left vulnerable to microbial invasion. Inducible innate immune response mechanisms exist to keep the wound site free from infection, thus allowing the wound to heal and the epidermis to re-establish its barrier function.

Since Varian (Econometrica 50:945–973, 1982; Review of Economic Studies 50:90–110, 1983) made checking for consistency with revealed preference conditions more accessible to empirical researchers; researchers have often used revealed preference procedures to test their maintained hypotheses and narrow the scope of their demand studies. The tests developed by Varian are for the direct utility funct

The standard pharmacological treatment for Parkinson's disease using the dopamine precursor levodopa is unfortunately limited by gradual development of disabling involuntary movements for which the underlying causes are poorly understood. Here we show that levodopa-induced dyskinesia in hemiparkinsonian rats is strongly associated with pronounced 80 Hz local field potential oscillations in the pri

It is important to identify patients who are at risk for infections with extended-spectrum β-lactamase (ESBL)-producing bacteria in order to reduce mortality, to avoid spread of resistant bacteria in hospitals, and to minimize the number of patients receiving unnecessary treatment with broad-spectrum antibiotics. A case-control survey among Swedish patients was performed at Skåne University Hospit

In this study, the transmission and reflection of two conductive fabrics are investigated in the frequency range from 2 to 18 GHz. One of the fabrics is a non-woven polypyrrole and the other consists of a polyethylene warp with steel threads in the weft. Reflection and transmission measurements are performed in order to characterize the electromagnetic properties of the materials. Reflection measu

Functional magnetic resonance imaging (fMRI) is a widely used tool for studying brain function in vivo. The technique is based on acquiring brain images sensitive to the physiological response following neural activation, and hence, allows brain activity to be examined and documented. In this thesis, methods for fMRI mapping of the primary somatosensory cortex (S1) are optimised and subsequent

Objectives: This paper describes the dietary intake of total fat, saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA) and cholesterol of participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) in 27 centres across 10 countries. Methods: Between 1995 and 2000, a stratified random sample of 36 034 participants (age range 35-74 years) complet

In this study, the spatial representativeness of eddy covariance (EC) methane (CH4) measurements was examined by comparing parallel CH4 fluxes from three short (6 m) towers separated by a few kilometres and from two higher levels (20 m and 60 m) at one location. The measurement campaign was held on an intensively managed grassland on peat soil in the Netherlands. The land use and land cover types