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BackgroundDiabetes mellitus (DM) poses a significant risk for the development of active tuberculosis (TB) and complicates its treatment. However, there is inconclusive evidence on whether the TB-DM co-morbidity is associated with a higher risk of developing multi-drug-resistant tuberculosis (MDR-TB). The aim of this meta-analysis was to summarize available evidence on the association of DM and MDR
BackgroundThe outpatient therapeutic care program (OTP) of children with severe acute malnutrition (SAM) has been decentralized to health post level in Ethiopia since 2008–2009. However, there is a lack of evidence regarding treatment outcomes and factors related to the duration of stay on treatment after its decentralization to health post level.ObjectiveThis study was aimed to assess treatment o
The Ambient-Pressure X-ray Photoelectron Spectroscopy (APXPS) endstation at the SPECIES beamline at MAX IV Laboratory has been improved. The latest upgrades help in performing photo-assisted experiments under operando conditions in the mbar pressure range using gas and vapour mixtures whilst also reducing beam damage to the sample caused by X-ray irradiation. This article reports on endstation upg
It is commonly assumed that personalization technologies used by Google for the purpose of tailoring search results for individual users create filter bubbles, which reinforce users’ political views. Surprisingly, empirical evidence for a personalization-induced filter bubble has not been forthcoming. Here, we investigate whether filter bubbles may result instead from a searcher’s choice of search
The 17 UN Sustainable Development Goals (SDGs) provide a framework for “peace and prosperity for people and the planet, now and into the future” (UN, 2015). Fast-moving societal questions as the ones related to the SDGs are often addressed from within traditional disciplinary research paradigms, which might not be best equipped for tackling the emerging challenges. At Lund University, an interdiscThe 17 UN Sustainable Development Goals (SDGs) provide a framework for “peace and prosperity for people and the planet, now and into the future” (UN, 2015). Fast-moving societal questions as the ones related to the SDGs are often addressed from within traditional disciplinary research paradigms, which might not be best equipped for tackling the emerging challenges. At Lund University, an interdisc
This study examines the articulation of anti-gender politics in the parliamentary debates centred on two citizens’ initiatives in Finland and Romania. Although different in their endeavours (in Finland, supporting equal marriage rights; in Romania, attempting to legislate pre-emptively against them), these citizens’ initiatives resulted in significant defeats for the wider anti-gender campaigns in
En klimapolitik der kun hviler på produktionssiden misser store klimapotentialer. Vi bliver derfor nødt til at huske forbrugssiden, skriver forskere fra Klima- og Omstillingsrådet i dette debatindlæg.
Repeated injury of the lung epithelium is proposed to be the main driver of idiopathic pulmonary fibrosis (IPF). However, available therapies do not specifically target the epithelium and human models of fibrotic epithelial damage with suitability for drug discovery are lacking. We developed a model of the aberrant epithelial reprogramming observed in IPF using alveolar organoids derived from huma
Extracellular vesicles (EVs) are derived from the membrane of platelets and released in the circulation upon activation or injury. Analogous to the parent cell, platelet derived EVs play an important role in hemostasis and immune responses by transfer of bioactive cargo from the parent cells. Platelet activation and release of EVs increases in several pathological inflammatory diseases, such as se
Social media and digital communication not only provide ways for organisations to engage stakeholders in new and more dialogic ways but have also opened a historically unprecedented Pandora’s box of disinformation techniques. Conventional crisis communication is well prepared to engage critical stakeholders, but its routines are ill-adapted to exploitative actors who employ deceptive or malicious
Min diktsamling fick 1a priset ex-æquo vid poesitävlingen "I Murazzi 2023". Priset bestod i en utgivning hos förlaget Genesi editrice.
One of the biggest challenges in urban densifications is securing adequate daylight access. This study examines the potential of using semantic 3D city models as input to daylight simulations. It is focusing on investigating input data requirements to these simulations from a geodata, 3D city model specification and measuring guideline perspective. To achieve this, geodata simulation input require
While fastidious microbes can be abundant and ubiquitous in their natural communities, many fail to grow axenically in laboratories due to auxotrophies or other dependencies. To overcome auxotrophies, these microbes rely on their surrounding cohort. A cohort may consist of kin (ecotypes) or more distantly related organisms (community) with the cooperation being reciprocal or nonreciprocal and expe
Biogenic production and release of methane (CH4) from thawing permafrost has the potential to be a strong source of radiative forcing. We investigated changes in the active layer microbial community of three sites representative of distinct permafrost thaw stages at a palsa mire in northern Sweden. The palsa site (intact permafrost and low radiative forcing signature) had a phylogenetically cluste
Functional attributes of microbial communities are difficult to study, and most current techniques rely on DNA- and rRNA-based profiling of taxa and genes, including microarrays containing sequences of known microorganisms. To quantify gene expression in environmental samples in a culture-independent manner, we constructed an environmental functional gene microarray (E-FGA) consisting of 13,056 mR
Thawing permafrost promotes microbial degradation of cryo-sequestered and new carbon leading to the biogenic production of methane, creating a positive feedback to climate change. Here we determine microbial community composition along a permafrost thaw gradient in northern Sweden. Partially thawed sites were frequently dominated by a single archaeal phylotype, Candidatus 'Methanoflorens stordalen
Permafrost contains about 50% of the global soil carbon. It is thought that the thawing of permafrost can lead to a loss of soil carbon in the form of methane and carbon dioxide emissions. The magnitude of the resulting positive climate feedback of such greenhouse gas emissions is still unknown and may to a large extent depend on the poorly understood role of microbial community composition in reg
Most free-living planktonic cells are streamlined and in spite of their limitations in functional flexibility, their vast populations have radiated into a wide range of aquatic habitats. Here we compared the metabolic potential of subgroups in the Alphaproteobacteria lineage SAR11 adapted to marine and freshwater habitats. Our results suggest that the successful leap from marine to freshwaters in
