Background: Patients and physicians both play an important role in the diagnosis of malignant melanoma. Objective: The purpose of this study was to assess important factors of delay in diagnosis at different centers and on three continents. Methods: Between October 2001 and October 2002, patients with histologically confirmed invasive melanoma were included in the study and given an established qu

Theoretical work on intraguild predation suggests that if a top predator and an intermediate predator share prey, the system will be stable only if the intermediate predator is better at exploiting the prey, and the top predator gains significantly from consuming the intermediate predator. In mammalian carnivore systems, however, there are examples of top predator species that attack intermediate

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with regard to its clinical course. The limitations of the methods currently available for prognostic assessment in CLL do not allow accurate prediction of the risk of disease progression in Individual patients. The recently developed cDNA array technique provides a unique opportunity to study gene expression in various malignancies. To

The aim of this study is to extend the traffic safety assessment concept to also include normal road user behaviour, thus not only exceptional behaviours such as accidents and serious conflicts. The goal is to provide a framework for a more thorough description and analysis of safety related road user behaviour in order to better understand the traffic safety processes. The traffic safety process

Artikel om ubåtar och ubåtskrigföring på film.

A calculation scheme with significant modifications and improvements for determining the ionization balance and the ion temperature evolution in an electron beam ion trap (EBIT) is presented. The scheme is applied to thorium, tantalum and oxygen ions using a specific set of EBIT operating parameters. The results of the calculation are compared to experiment and previous calculations. Rates for the

This study observed the public health nurse's and the patient's activity level during blood pressure measurement and the kind of nonpharmacological treatment that was given. Using the Nurse Practitioner Rating Form, three structured observations were made of 21 public health nurses at their offices at health care centers. The nurses were randomly selected from 22 health care centers in Southern Sw

Three commercially available, peptide-based enzyme-linked immunosorbent assay (ELISA) systems (Chlamydia trachomatis IgG and IgA EIA [CT-EIA; Labsystems OY, Helsinki, Finland], SeroCT IgG and IgA [SeroCT; Savyon Diagnostics Ltd., Ashdod, Israel], and Chlamydia trachomatis IgG and IgA pELISA [CT pELISA; Medac, Wedel, Germany]) were evaluated for the detection of serum immunoglobulin G (IgG) and IgA

To assess the efficacy and long-term effects of glipizide treatment on glucose and insulin metabolism in individuals with impaired glucose tolerance (IGT). Thirty-seven first-degree relatives of patients with type 2 diabetes fulfilling WHO criteria for IGT were randomized to treatment with either glipizide 2.5 mg once daily or matching placebo for 6 months. A 75 g, 2-h oral (OGTT) and 60 min intra

The concept of critical loads has been an important and successful tool for the development of control strategies for transboundary air pollution in Europe. The use of the concept has led us to a situation where very few areas in Europe will have an exceedance of critical loads for acidification in 2010, indicating that the benefits of further control acidifying substances will be less useful. The

The interaction between cystatin C variants, in which the evolutionarily conserved Gly-11 residue was substituted by Ala, Glu or Trp, and the cysteine proteinases, papain, ficin, actinidin and cathepsin B, was characterized. The substitutions reduced the affinity of binding in a manner consistent with the Gly residue of the wild-type inhibitor, allowing the N-terminal region to adopt a conformatio

I föreliggande rapport redovisas resultat från en brett upplagd laboratorieundersökning av ett stort antal vattenavvisande preparat.

In the present work we determine the adsorption site of two polyatomic molecules, methoxy and ethoxy, on Cu(100). This is accomplished by comparing experimental intramolecular vibrational modes to the corresponding modes calculated by first principle methods. We explore the three different high symmetry adsorption sites on top, bridge and hollow using several different metal clusters to represent

Time-resolved absorption spectroscopy was used to study the femtosecond and picosecond time scale electron injection from the excited singlet and triplet states of Ru(dcbpY)(2)(NCS)(2) (RuN3) into titanium dioxide (TiO2) nanocrystalline particle film in acetonitrile. The fastest resolved time constant of similar to30 fs was shown to reflect a sum of two parallel ultrafast processes, nonergodic ele

Background and Purpose-The proportion of immigrants has increased in Sweden markedly during the last decades, as in many other Western countries. Incidence of stroke has increased during this period. However, it is primarily unknown whether incidence of stroke and stroke subtypes in Sweden is related to country of birth. Methods-Incidence of first-ever stroke was followed during 10 years in a coho

In the licentiate thesis my starting point is the Social Service Act and specifically, chapter 6, paragraph 5 which directs one to primarily consider the suitability of placing a child with a relative or a person known to the family. The objective of the thesis is to examine how the topic concerning placement with relatives arose and how the regulation reflects on child care within social work. An

Upon encounter with antigen, the B lymphocyte population responds by producing a diverse set of antigen-specific antibodies of various isotypes. The vast size of the responding populations makes it very difficult to study clonal evolution and repertoire composition occurring during these processes in humans. Here, we have explored an approach utilizing the H-EPSILON-encoding transcriptome to inves