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We revisit the discussion on family limitation through stopping and spacing behavior both prior to and during the fertility transition. Using the birth histories of 13 519 settler women in nineteenth century South Africa we find no evidence of parity specific spacing prior to the transition. In addition we find no differences in spacing behavior based on differences in time invariant economic and

This study investigates the long-term social consequences of early-life exposure to adverseconditions in nineteenth-century Poznań. Using linked individual-level records from thePoznań Historical Population Database for birth cohorts 1830–1855, we examine howprenatal stress, infant mortality, early-childhood disease burden, and fluctuations in rye pricesinfluenced the likelihood of marriage and in

Bacteriophages exert strong selective pressure on bacterial populations and play a central role in shaping microbial evolution. In response to phage predation, bacteria have evolved diverse antiphage defence mechanisms that interfere with viral replication through a wide range of molecular strategies. Recent genomic studies have revealed a rapidly expanding repertoire of candidate defence systems,

BackgroundImmune-related hepatitis (ir-hepatitis) ranks among the most frequent adverse events of immune checkpoint inhibitors (ICIs). Limited knowledge exists regarding the incidence, characteristics, and treatment of patients having an inadequate response to initial therapy with steroids. Characterizing ir-hepatitis phenotypes and treatment responses can provide valuable insights for guiding tre

BACKGROUND AND PURPOSE: Pain as a long-term outcome following rectal cancer treatment has received limited attention in previous studies. This prospective cohort study examined pain prevalence up to 5 years post-surgery in patients treated with curative intent. Secondary aims included evaluating pain intensity and its interference with daily life, and comparing pain experiences with a reference po

The HLD-NAC (Hydrophilic-Lipophilic Difference - Net Average Curvature) equation of state is a powerful semi-empirical framework used to predict the phase behavior, solubilization, and interfacial properties of surfactant-oil-water (SOW) systems it is based on the assumption of a normalized curvature for an idealized microemulsion, represented as the coexistence of two fictitious phases: water dro

This essay argues that the concept of global responsibility, as articulated in the works of Karl Jaspers and Hans Jonas, was anticipated in Günther Anders' 1956 opus, Die Antiquiertheit des Menschen. By tracing the phases of Anders' negative anthropology—from his pathology of freedom to the Promethean differential andhis critique of what he considers to be an annihilistic Western stance—I examine

Review of the documentary film "Psychedelic Psalm"

While tau pathology is closely associated with neurodegeneration in Alzheimer's disease (AD), our prior work using multi-modality imaging revealed that mismatch between tau (T) and neurodegeneration (N) may reflect contributions from non-AD processes. The medial temporal lobe (MTL), an early site of AD pathology, is also a common target of co-pathologies such as limbic-predominant age-related TDP-

Abstract – Background: Cytological examination of a fine-needle aspirate (FNA) is a minimally invasive modality that is increasingly used in the diagnosis of lymphoma. Flow cytometry and other ancillary tests make an important contribution to the diagnostic value of FNAs of lymphoid lesions. This review follows the recent publication of the first edition of the WHO Reporting System for Lymph Node,

This pioneering volume explores complex local, global and digital contexts from the perspectives of Digital Theology.The use of and access to digital technology is highly contextual. It differs between regions, generations, classes, religious denominations, and gender. Which problems theologians claim to be important and which developments they ignore is contingent on their cultural, social, econo

This chapter gives an overview of the discussions on online preaching. It identifies and provides examples of three common approaches—message-oriented, media-oriented, and ontology-oriented. In addition, it points to a fourth approach that might be fruitful: the practice-oriented. The chapter also suggests four critical areas in which digital homiletics could benefit from being further developed: