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A novel hollow-fibre microporous membrane liquid-liquid extraction for determination of free 4-isobutylacetophenone concentration at ultra trace level in environmental aqueous samples

In this study, a method was developed for determination of the free concentration of 4-isobutylacetophenone, a toxic degradation product of ibuprofen, in river and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up and gas chromatography-mass spectrometry (GC-MS), respectively. In this n

Globalization and risky human-capital investment

Globalization is supposed to increase the mobility of highly skilled labor and to reduce governments' scope for redistribution. We show that this increases the private incentives for education and may decrease, but may also increase, the government's incentives to provide education subsidies in a framework in which education investment is risky. Globalization shifts the cost of these subsidies to

Multiple Windows for Estimation of Locally Stationary Transients in the Electroencephalogram

In this paper, multiple windows, optimal for locally stationary processes (MW-LSP) are used to estimate the spectrogram of the electroencephalogram (EEG) where we focus on the ability to estimate transient frequency changes. A peak of known frequency was evoked in the EEG spectrum in a predetermined time interval, by using a 9 Hz flickering light. We investigate the multiple windows corresponding

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Stabilization of the state of equilibrium of affine system controlled by saturating control is investigated. Saturating stabilizing control is designed by means of rescaling of control laws after linearization of the system under feedback control. A method for estimation of the stabilized region of state space is provided. As an example, a solution to the task of stabilization of the orientation o

Bose-Einstein correlations in W+W- events at LEP2

Bose-Einstein correlations (BEC) between final state particles in the reaction e(+)e(-) -> W+ W- -> q(1)(q(2)) over barq(3)(q(4)over bar>) over bar) have been studied. Data corresponding to a total integrated luminosity of 550 pb(-1), recorded by the DELPHI detector at centre-of-mass energies ranging from 189 to 209 GeV, were analysed. An indication for inter-W BEC between like-sign particles has

Loss of size-selectivity of the glomerular filtration barrier in rats following laparotomy and muscle trauma.

Post-traumatic microalbuminuria may be caused by either charge- or size-selective alterations in the glomerular filtration barrier, or both, and/or to a reduction in proximal tubular protein reabsorption (PTR). This study was performed to elucidate the pathophysiology of the increases in glomerular permeability occurring in rats exposed to laparotomy or to laparotomy and muscle trauma. In anaesthe

Effects of pH management during selective antegrade cerebral perfusion on cerebral microcirculation and metabolism: alpha-stat versus pH-stat

BACKGROUND: Selective cerebral perfusion (SCP) is used for extending the period during which surgical procedures can be safely performed. We sought to determine the direct effects of pH management on cerebral microcirculation and metabolism during SCP. METHODS: An experimental SCP porcine model was created by selectively allowing cold perfusate only into the bicarotid brachiocephalic trunk during

Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis

Tissue factor (TF) is the cellular receptor for factor FVIIa (FVIIa), and the complex is the principal initiator of blood coagulation. The effects of FVIIa binding to TF on cell migration and signal transduction of human fibroblasts, which express high amounts of TF, were studied. Fibroblasts incubated with FVIIa migrated toward a concentration gradient of PDGF-BB at approximately 100 times lower

Effect of bioactive polypeptides on leaking large bowel anastomosis and intestines in the rat.

Anastomotic leakage and postoperative adhesions represent major complications after colorectal surgery. We have previously shown a positive effect on both anastomotic strength and abdominal adhesions by the use of differently charged bioactive polypeptides. The present study aimed to investigate the effect of the same polypeptides on the healing of an insufficient intestinal anastomosis, as well a

Disc Hemorrhages and Treatment in the Early Manifest Glaucoma Trial.

PURPOSE: To evaluate the effect of intraocular pressure (IOP)-reducing treatment on the development of disc hemorrhages in patients with glaucoma. DESIGN: Prospective cohort study of patients in the Early Manifest Glaucoma Trial, followed up to 11 years (median = 8 years). PARTICIPANTS: Patients with newly detected glaucoma randomized to argon laser trabeculoplasty plus betaxolol (n = 129) or no i

The accuracy of migration distance measures

The spatial dimension in the definition of internal migration usually refers to the distance someone has tomove to be regarded as a migrant. Lack of precise data on migration distances, however, has obliged migration researchers to use aggregate distance measures whose accuracy is largely unknown, raising potentially serious validity concerns for research. The aim of this paper is to examine the a

Postprandial blood glucose response in relation to gastric emptying and satiety in healthy subjects.

Glucostatic appetite regulation has numerous determinants, among others: cephalic phase digestion, gastric emptying and absorption, together influencing postprandial blood glucose responses and satiety. This short communication presents and reviews studies of gastric emptying, antral distension and postprandial glucose response and their relation to reports of satiety in healthy non-obese over nig