Establishment and Evaluation of Affinity Reagents for Mass Spectrometry Based Proteomic Studies on Lysine Methylation
Methylation of lysine (Kme) is known to regulate several important functions, altering gene expression and cell cycle progression. However, mass spectrometry based proteomic analysis of the modification has not been possible due to the lack of efficient purification strategies to enrich modified peptides for analysis. In this study, we identified and evaluated several in-house and commercial candi
