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A Multidisciplinary Assessment of Children with Severe Language Disorder

This study presents results from a multidisciplinary assessment of ten Swedish children with severe language disorder, aged 4;4-10;0. The children underwent an extensive medical examination. They were also tested by a clinical child psychologist. A thorough neurolinguistic examination was done as well as detailed linguistic analyses of the children's speech production. The results of our study rev

Coalitions in EU negotiations

Coalitions will probably become an increasingly important theme in European Union (EU) politics. The spread of decision making by majority voting promotes coalition-building behaviour. The impending enlargement is predicted to differentiate and polarize policy standpoints within the EU. Increasing levels of policy conflict imply increased propensities for coalition building. Still, the role and na

DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E

The present work investigates the occurrence and significance of aberrant DNA methylation patterns during early stages of atherosclerosis. To this end, we asked whether the genetically atherosclerosis-prone APOEnull mice show any changes in DNA methylation patterns before the appearance of histologically detectable vascular lesion. We exploited a combination of various techniques: DNA fingerprinti

Experiences of stigma among people with severe mental illness. Reliability, acceptability and construct validity of the Swedish versions of two stigma scales measuring devaluation/discrimination and rejection experiences

Stigma has been identified as one of the most important obstacles for a successful integration of people with mental illness into the society. Research about stigma has shown negative attitudes among the public towards people with mental illness. Studies so far have, however, put little emphasis on how these negative attitudes are perceived by the mentally ill persons. The aim of the present study

OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis

Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee,

The Malmo International Brother Study (MIBS): further support for genetic predisposition to inhibitor development in hemophilia patients

The issue of factors predisposing for inhibitor development in haemophilia patients is still largely unresolved. In an attempt to address this problem, we initiated a registry in 1996 of siblings with haemophilia and with or without a history of inhibitors. Four hundred and sixty families have accrued, of whom 388 suffer from haemophilia A and 72 haemophilia B. Twenty-five of the brother pairs are

Systemic interleukin-6 response to colorectal surgery originates from the bowel.

Background: Surgical trauma evokes a systemic cytokine response which is enhanced in patients with colorectal cancer. The aim of this study was to locate the origin of the systemic cytokine response to colorectal surgery. Methods: The concentrations of interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) were analysed in systemic and mesenteric venous blood in 12 patients operated on

Revealing the mechanisms of sexual isolation in a case of sympatric and parallel ecological divergence

Two ecotypes of a marine intertidal snail (Littorina saxatilis), living at different microhabitats and shore levels, have evolved in sympatry and in parallel across the Galician rocky shore. These ecotypes differ in many traits (including size) due to differential adaptation. They meet, mate assortatively, and partially hybridize at the mid shore where the two microhabitats overlap. The partial se

Insulin and free oestradiol are independent risk factors for benign prostatic hyperplasia

The aetiology of benign prostatic hyperplasia (BPH) remains unclear. The objective of the present study was to test the insulin, oestradiol and metabolic syndrome hypotheses as promoters of BPH. The design was a risk factor analysis of BPH in which the total prostate gland volume was related to endocrine and anthropometric factors. The participants studied were 184 representative men, aged 72-76 y

Calculating the soot particle size distribution function in turbulent diffusion flames using a sectional method

Soot formation in a turbulent jet diffusion flame is modeled using an unsteady flamelet approach in post-process. In the present work, we apply a detailed kinetic soot model with a sectional method, and study the evolution of the particle size distribution. Detailed information on the evolution of the soot particle size distribution function is acquired. It is found that the particle size distribu

Propofol sedation and gastric emptying in volunteers

BACKGROUND: The purpose of this study was to evaluate the effects of light propofol sedation on gastric emptying and orocecal transit time (OCT). METHODS: Ten healthy male volunteers were studied on 2 occasions separated by at least 1 week and were randomly allocated to receive either propofol sedation or i.v. saline as a control. During propofol sedation the volunteers were sedated to grade 2-3 o

Incorporating Forecasts of Rainfall in Two Hydrologic Models Used for Medium-Range Streamflow Forecasting

This study reports on the performance of two medium-range streamflow forecast models: (1) a multilayer feed-forward artificial neural network; and (2) a distributed hydrologic model. Quantitative precipitation forecasts were used as input to both models. The Furnas Reservoir on the Rio Grande River was selected as a case study, primarily because of the availability of quantitative precipitation fo

Re-evaluation of clinical dementia diagnoses with pittsburgh compound B positron emission tomography.

There is an overlap regarding Pittsburgh compound B (PIB) retention in patients clinically diagnosed as Alzheimer's disease (AD) and non-AD dementia. The aim of the present study was to investigate whether there are any differences between PIB-positive and PIB-negative patients in a mixed cohort of patients with neurodegenerative dementia of mild severity regarding neuropsychological test performa

High resolution sparse estimation of exponentially decaying signals

We consider the problem of sparse modeling of a signal consisting of an unknown number of exponentially decaying sinusoids. Since such signals are not sparse in an oversampled Fourier matrix, earlier approaches typically exploit large dictionary matrices that include not only a finely spaced frequency grid but also a grid over the considered damping factors. The resulting dictionary is often very

Torrötning av rejekt från förbehandling av matavfall.

När källsorterat matavfall från hushållen rötas i en biogasanläggning av modellen omrörd tank behövs en förbehandling för att göra materialet pumpbart och ta bort orenheter. En typ av förbehandling innebär att avfallet passerar genom en skruvpress som delar avfallet i en pumpbar fraktion och en torr fraktion, så kallat rejekt. På NSR förbehandlas matavfallet med denna teknik och rejektet skickas i