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Chronic pancreatitis is a common disorder of which the underlying pathogenic mechanisms still are incompletely understood. In the last decade, increasing evidence has shown that activated pancreatic stellate cells play a key role in the fibrosis development associated with chronic pancreatitis as well as pancreatic cancer. During pancreatic injury or inflammation, quiescent stellate cells undergo
Apolipoprotein M (apoM) is a novel apolipoprotein found mainly in high-density lipoproteins (HDL). Its function is yet to be defined. ApoM (25 kDa) has a typical lipocalin beta-barrel fold and a hydrophobic pocket. Retinoids bind apoM but with low affinity and may not be the natural ligands. ApoM retains its signal peptide, which serves as a hydrophobic anchor to the lipoproteins. This prevents ap
Context: Effect of GH therapy in short non GH deficient children, especially idiopathic short stature (ISS) has not been clearly established owing to lack of controlled trials until final height (FH). Objective: To investigate the effect of two GH doses compared with untreated controls on growth to FH in short children mainly with ISS. Design and Setting: A randomized, controlled, long-term multic
Detta är det första av tre inlägg för att ge perspektiv på IKT i matematik- undervisningen. Bakgrunden till inlägget är en nyligen släppt rapport från Skolverket, som visar att användningen av IKT är i stort sett lika låg i flera ämnen, som den var för tre år sedan. Det är, enligt rapporten, fortfarande ovanligt att eleverna använder datorer på lektioner i matematik. Det finns inte heller någon ty
Review of Markus Dahlberg (ed), “Sockenkyrkorna. Kulturarv och bebyggelsehistoria” (Stockholm 2008)
The social consequences of agrarian change have been widely debated. The traditional view of the lower classes becoming increasingly vulnerable due to the loss of access to resources has been met with the revisionist view that this change was counteracted by an increase in the volume and regularity of employment due to investments and new farming practices. This article address this issue by study
Advanced fibrosing interstitial lung disease (ILD) is often progressive and associated with a high burden of symptoms and poor prognosis. Little is known about the symptom prevalence and access to palliative care services at end of life (EOL).
The Lande g(J) factors in the 6snd(1,3)D(2) sequences as well as states from the perturbing configurations of neutral Ytterbium have been measured by time-resolved fluorescence spectroscopy. Strong singlet-triplet mixing effects were observed. The g(J) factors were measured using the Zeeman quantum-beat technique following step-wise laser excitation. The experiment provided new data for checking t
Denna rapport handlar så mycket om "Internet inifrån" att titeln gav sig själv – det var bara det att "Internet Inifrån"-titeln redan är upptagen. Den finns sedan i fjol som beteckning på en LTH-kurs som ges i samarbete med företaget AXIS. Denna har ett renodlat inifrånperspektiv ur teknisk synvinkel. I vår kurs kommer inifrånperspektiven däremot från dem som lär sig med hjälp av Internet. Man är
