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An investigation of Thapsia garganica afforded a series of tetracyclic C-19 dilactones, whose production was dependent on the time and location of the collection. These unusual tetrahomosesquiterpenoids are presumably biosynthesized via a carbon dioxide-triggered electrophilic polyolefin cyclization. Despite the structural differences with thapsigargin, these compounds showed SERCA-inhibiting prop

The effect of loss of bond for longitudinal reinforcement on the structural behavior of RC beams is investigated in a test series of six beams where nominal length without bond is varied. Loss of bond is created with plastic tubes surrounding the longitudinal reinforcement leaving short bonded lengths over support and at positions where stirrups are crossing the longitudinal reinforcement. Using a

This thesis deals with the development of the DP (the Determiner Phrase) in bilingual first (2L1) and in adult second (L2) language acquisition of French. The thesis shows that the children and the adult Swedish learners acquire syntactic categories differently: the children follow a structural economy principle in positing as small categories as possible (Rizzi, 1998). The adult learners aim to

This is a historical account of the development of the concept frontotemporal dementia, beginning with our discovery in the late 60s of a simple degenerative form. It was named frontal lobe degeneration of non-Alzheimer type to clearly separate it from the then almost totally dominating diagnosis Alzheimer disease. In the absence of immunohistochemical methods for specific disease markers, we had

PURPOSE: This Swedish multicenter trial was performed on patients with known or suspected lesions of the CNS for which an MR examination using a contrast medium was indicated. A total of 8 MR centers participated in the study to establish the safety and efficacy of Omniscan (gadodiamide injection) in clinical routine using a standard dose of 0.1 mmol Gd/kg b.w. MATERIAL AND METHODS: Seven hundred

A general approach to exploratory analysis and modeling of network data is to investigate dyad distributions. We discuss clustering of dyad distributions when there are several variables defined on the vertices, and these variables interact with the arc values of the network. As an illustration we use data on achievement, race, sex and friendship for children in 48 different school classes. A clus

Hereditary cystatin C amyloid angiopathy (HCCAA) is an autosomal dominant disorder leading to massive brain hemorrhage and death in young adults (Jensson et al., 1987). A variant of a potent inhibitor of cysteine proteinases, cystatin C (Barrett et al., 1984), is deposited as amyloid fibrils in the cerebral arteries of the patients (Ghiso et al., 1986). We have used the full length cystatin C cDNA

A need for a hand-ergonomics training kit has been identified to increase critical thinking concerning choice of hand tools. This study deals with the design, use and evaluation of a hand-ergonomics training kit for use in ergonomics training programmes. The effects on awareness of hand ergonomics among training course participants have been evaluated by means of a questionnaire and interviews at

The use of topographical data in hydrological and agricultural applications has increased with GPS data availability and the concept of precision agriculture. This thesis investigates the relationships between topography and in one case simulated soil moisture and in the other case yield. The yield was recorded with a new optical sensor, which uses a digital camera to detect objects and records th

The crustacean cuticle has numerous projections and some of these projections, the setae, have important mechanical as well as sensory functions. The setae display a wide diversity in their external morphology, which has led to great problems separating setae from other projections in the cuticle and problems in making a consistent classification system. Here, the cuticular projections on the mout

This report presents results regarding fear of crime amongst young people in a small Swedish town, Ljungby. It also considers the experience of violence and other types of crime. A questionnaire was distributed to 320 students in upper secondary school during October 2001. The results from these questionnaires shows that female students more often than male students state that they are worried whe

Objectives: To identify genetic and non-genetic risk factors for papillary serous uterine cancer. Methods: A case-control study was conducted. Case women with papillary serous uterine cancer were compared with two control groups: 1) women with endometrioid uterine cancer and 2) healthy women with no past history of cancer. Cases and controls were matched for age (within two years) and ethnic group

Metal-organic chemical vapour deposition growth of titanium oxide on moderately pre-oxidised Si(1 1 1) using the titanium(IV) isopropoxide precursor has been studied for two different growth modes, reaction-limited growth at 300 degrees C and flux-limited growth at 500 degrees C. The interfacial properties have been characterized by monitoring synchrotron radiation excited Si 2p photoemission spec

The performance of a 5' nuclease real-time PCR assay was studied to optimize an automated method of detection of preenriched Salmonella enterica cells in buffered peptone water (BPW). The concentrations and interactions of the PCR reagents were evaluated on the basis of two detection responses, the threshold cycle (C(T)) and the fluorescence intensity by a normalized reporter value (DeltaR(n)). Th

Gene therapy holds great promise for treating many genetic diseases, including muscular dystrophies. Mutations in the gene encoding laminin alpha2 chain ? an extracellular protein prominently expressed in the neuromuscular system ? cause a severe neuromuscular disorder: congenital muscular dystrophy type 1A (MDC1A). Currently, there is no treatment for MDC1A. Preclinical studies are the first step

Children's utilization of curative care was studied to analyse the division of responsibilities between undifferentiated primary care and specialized care. All chronically ill (n = 510), a control group (n = 287) and the total population 0-15 years of age (n = 6080) in a primary care district were studied using register data. Chronically ill children comprised 8.4% of the total child population an

In this paper we present a novel method for predictive coding with application to transmission of speech over packet-switched networks. Our method uses multiplexing to distribute a part of the information about a segment of each speech signal in several data packets while keeping the data packet rate and payload for that part of the information unchanged. We investigate three multiplexing schemes: