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Comparative Analysis of Pharmacokinetic-Pharmacodynamic Models for Propofol and Remifentanil Using Model Predictive Control

This study aims to compare the effectiveness of different Pharmacokinetic-Pharmacodynamic (PK-PD) models for administering Propofol and Remifentanil, two critical agents in anesthesia. Initially, different PK models were introduced: one for Propofol based on the Schnider model and another for Remifentanil using the Minto model. Alternatively, both drugs were modeled using the Eleveld models. The P

Ethnographies of global health governance and diplomacy : A practical guide

n the past two decades, medical anthropology has increasingly turned its attention to the global, including ethnographic fieldwork at global health mega-events and the processes behind global health initiatives. Similar developments have taken place in political and legal anthropology, with researchers looking at United Nations organizations, transnational epistemic communities, and other global s

Critical needs to close monitoring gaps in pan-tropical wetland CH4 emissions

Global wetlands are the largest and most uncertain natural source of atmospheric methane (CH4). The FLUXNET-CH4 synthesis initiative has established a global network of flux tower infrastructure, offering valuable data products and fostering a dedicated community for the measurement and analysis of methane flux data. Existing studies using the FLUXNET-CH4 Community Product v1.0 have provided inval

Acoustic Trapping of Extracellular Vesicles

Extracellular vesicles (EVs) are membrane enclosed biological nanoparticles released by cells. In the past two decades, EVs have gained a lot of attention due to their role in numerous biological processes. However, their small nature complicates isolating them from biological fluids with cumbersome techniques, such as ultracentrifugation. Acoustic trapping is a technique that uses ultrasonic stan

Extravert Surgical Resident Applicants Get Higher 360-Degree Evaluations From Coworkers

INTRODUCTION: 360-degree evaluations are used as an assessment in order to identify strengths and weaknesses of, or as a continuous evaluation for, residents. The aim of this study was to investigate the relationship between personality and ratings on 360-degree evaluations among surgical residency applicants. A secondary aim was to describe the personality profile of applicants for a surgical res

Looking back at the TEDDY study : lessons and future directions

The goal of the TEDDY (The Environmental Determinants of Diabetes in the Young) study is to elucidate factors leading to the initiation of islet autoimmunity (first primary outcome) and those related to progression to type 1 diabetes mellitus (T1DM; second primary outcome). This Review outlines the key findings so far, particularly related to the first primary outcome. The background, history and

Investigation of the combustion characteristics and knock tendencies of neat C1–C4 alcohol fuels using a CFR engine

Even though it is primarily used in blends with gasoline, neat ethanol is considered an excellent fuel for spark-ignition engines, as demonstrated by its widespread use as a transportation fuel in Brazil. The use of biologically produced alcohols in neat form has the potential to displace larger amounts of fossil fuels, compared to using them solely as oxygenate blend components. Consequently, fur

Lubunya Assemblages : Queer Networked Resistances in Turkey

Den här avhandlingen undersöker hur digital teknik påverkar queeraktivismoch rum för motstånd i dagens Turkiet. Genom att studera nätverksbaserademotståndspraktiker som sträcker sig över tid och som finns både online ochoffline, syftar avhandlingen till att utforska hur digital teknologi har präglatqueera motståndskulturer. Målsättningen är att bidra till akademiska debatterom ontologiska och episFrom a multi-sited ethnographic perspective, I analyse the impacts of digital technologies on queer activism in contemporary Turkey with a focus on networked resistance practices such as Pride activism and queer knowledge production at the digital level. By so doing, I aim to explore how queer spaces of resistance and practices of sexual citizenship are (re)articulated within a context of heteropa

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The need to make young scientists aware of their social responsibilities is widely acknowledged, although the question of how to actually do it has so far gained limited attention. A 2-day workshop entitled "Prepared for social responsibility?" attended by doctoral students from multiple disciplines in climate science, was targeted at the perceived needs of the participants and employed a format t