Climate change adaptation, which has previously been seen as a national and local matter, is today systematically addressed by international institutions such as the UNFCCC, the FAO and the WTO. Research has focused on the overarching institutional architecture of global adaptation, particularly how it relates to development, political economy, efficiency and equity. In contrast to the transnation

This article aims to apply convergence, a new media concept, to tourism studies in order to enhance the understanding of tourists' agency in destination marketing. Tourists create media products/images which circulate online through various channels like social media. These products are then available for consumption by other tourists, which in turn influences new media products. They all become p

Understanding neurocognitive mechanisms supporting the use of multiple languages is a key question in language science. Recent neuroimaging studies in monolinguals indicated that core language areas in human neocortex together with sensorimotor structures form a highly interactive system underpinning native language comprehension. While the experience of a native speaker promotes the establishment

TP53 mutations in the absence of 17p-deletion correlate with rapid disease progression and poor survival in chronic lymphocytic leukemia (CLL). Herein, we determined the TP53 mutation frequency in 268 newly diagnosed CLL patients from a population-based material. Overall, we detected TP53 mutations in 3.7% of patients (n = 10), where 7/10 cases showed a concomitant 17p-deletion, confirming the hig

Abstract in UndeterminedPurpose – This paper seeks to develop an integrated framework to examine how entrepreneurs' work experience is associated with the generation of new business ideas. The framework combines human capital theory with theory and research on entrepreneurial learning.Design/methodology/approach – A statistical analysis on a sample of 291 Swedish entrepreneurs is conducted.Finding

A drawback when hobbing lead crowned helical gears is that the gear tooth will be manufactured with alignment errors, often denoted flank twist. Together with other source deviations, these errors must not exceed the predetermined tolerances if the gear is to be finished hobbed. A simulation model is developed where the hobbing process can be analysed without additional errors resulting from real

Hemophilia A is a congenital, recessive, X-linked bleeding disorder that is managed with infusions of plasma-derived or recombinant factor (F) VIII. The primary considerations in FVIII replacement therapy today are the: 1) immunogenicity of FVIII concentrates, 2) role of longer-acting FVIII products, 3) prophylactic use of FVIII in children and adults with severe hemophilia A, and 4) affordability

Lipase-catalyzed ethanolysis of triolein was studied as a model for biodiesel production. Four lipases were immobilized on porous polypropylene, and ethanolysis reactions were carried out in methyl t-butyl ether. The reaction products were analyzed using gas chromatography. Three of the four lipases studied were efficient in the conversion of triolein to 2-monoolein, but slow in the final step of

Feedforward from measurable disturbances is a powerful complement to feedback control to improve disturbance rejection capability. Recent works have remarked the necessity of a design strategy for those cases where the ideal feedforward controller is not realizable. In this paper, a simple shaping design procedure is presented together with straightforward rules to obtain optimal feedforward contr

Fabry disease (FD) may cause stroke and is reportedly associated with typical brain findings on magnetic resonance imaging (MRI). In a large group of young patients with an acute cerebrovascular event, we wanted to test whether brain MRI findings can serve to suggest the presence of FD.

Energy selective neutron radiography was performed to describe a complex structure in polycrystalline materials. Experiments were performed with currently the highest energy and spatial resolutions achieved simultaneously, by employing a double crystal monochromator for selecting narrow energy bands from the initially polychromatic neutron beam and the neutron absorbing scintillator screen coupled

The females of the four continental Greenomyia Brunetti species in Europe are associated with the males, diagnosed and keyed, providing the first association and description of the females of G. baikalica Zaitzev, 1994 and G. stackelbergi Zaitzev, 1982. Colour photographs of their habitus and line drawings of their female terminalia are provided. Greenomyia mongolica Lagtovka & Matile, 1974 is

All animals flap their wings in powered flight to provide both lift and thrust, yet few human-engineered designs do so. When combined with flexible wing surfaces, the resulting unsteady fluid flows and interactions in flapping flight can be complex to describe, understand, and model. Here, a simple modified actuator disk is used in a quasi-steady description of the net aerodynamic lift forces on s

The purpose of the study was to explore the role of the physical environment for creative employees. The results are based on interviews with office-working digital artists. The physical work environment was considered to offer three types of support for creative work for the participants: functional, psychosocial, and inspirational. Creative processes would find better breeding ground if function

Objectives The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components. Background It is unclear whether the LPA variants rs10455872 and rs3798220, which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis

The aim of this study was to determine, through a genome-wide association study (GWAS), the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis (SSc). We considered limited (IcSSc) and diffuse (dcSSc) cutaneous involvement, and the relationships with presence of the SSc-specific auto-antibodies, anti-centromere (ACA), and anti-topoisomerase I (ATA). Four GWAS

ABSTRACT: Streptococcal toxic shock syndrome is most frequently associated with Streptococcus pyogenes of the M1 serotype. Simvastatin protects against M1 protein-induced acute lung damage, although downstream mechanisms remain elusive. Herein, we hypothesized that geranylgeranylation might regulate proinflammatory effects in M1 protein-induced lung injury. Male C57BL/6 mice received the geranylge

Background: Extended-spectrum beta-lactamase (ESBL)-producing bacteria are an escalating problem threatening health. Devastating consequences can result in neonatal intensive care units (NICU) due to these bacteria. The aim of this study was to investigate the efficacy of once-a-week screening (July 2010 to September 2012) versus screening on demand (April 2008 to June 2010). Materials and methods