Filetype
Colorectal cancer is one of the leading causes of death worldwide. Polyps are early symptoms of colorectal cancer and prone to malignant transformation. Polyp segmentation of colonoscopy images can help diagnosis. However, existing studies on polyp segmentation of colonoscopy images face two main difficulties: blurry polyp boundaries, close resemblances between polyps and surrounding tissues. The
We investigate the collective dynamics of a population of X Y model-type oscillators, globally coupled via non-separable interactions that are randomly chosen from a positive or negative value and subject to thermal noise controlled by temperature T. We find that the system at T = 0 exhibits a discontinuous, first-order like phase transition from the incoherent to the fully coherent state; when th
PurposeDrylands account for 47.2% of land area and contain 15.5% of global carbon (C). However, the variation in organic and inorganic C stocks across latitudinal gradients in arid and semiarid shrubland ecosystems remains understudied, and we lack in-depth understanding of the main drivers of C variation at this spatial scale.MethodsHere, we sampled soils from 95 sites across a latitudinal gradie
Introduction: A decrease in ischemic stroke (IS) incidence has been observed in high income countries during the last decades. Whether this has influenced the occurrence of aphasia in IS is uncertain. We therefore examined the incidence rate and potentially related determinants of aphasia in IS. Methods: We prospectively examined consecutive patients admitted to hospital with first-ever acute IS b
Increasing climatic and human pressures are changing the world's water resources and hydrological processes at unprecedented rates. Understanding these changes requires comprehensive monitoring of water resources. Hydrogeodesy, the science that measures the Earth's solid and aquatic surfaces, gravity field, and their changes over time, delivers a range of novel monitoring tools that are complement
Climate change is expected to increase woody vegetation abundance in the Arctic, yet the magnitude, spatial pattern and pathways of change remain uncertain. We compared historical orthophotos photos (1952 and 1979) with high-resolution satellite imagery (2015) to examine six decades of change in abundance of white spruce Picea glauca and tall shrubs (Salix spp., Alnus spp.) near the Agashashok Riv
Operating enormous, integrated refineries and clusters, the petrochemical industry runs processes in which hydrocarbons are turned into the fundamental components for plastics and other synthetic materials. Continuing a historical trend of consistent output growth, petrochemicals are the largest current driver of oil demand growth. At the same time, the industry is under increasing pressure to tra
Immunotherapies with antibody-drug-conjugates (ADC) and CAR-T cells, targeted at tumor surface antigens (surfaceome), currently revolutionize clinical oncology. However, target identification warrants a better understanding of the surfaceome and how it is modulated by the tumor microenvironment. Here, we decode the surfaceome and endocytome and its remodeling by hypoxic stress in glioblastoma (GBM
Inhalation therapy treating severe infectious disease is among the more complex and emerging topics in controlled drug release. Micron-sized carriers are needed to deposit drugs into the lower airways, while nano-sized carriers are of preference for cell targeting. Here, we present a novel and versatile strategy using micron-sized spherical particles with an excellent aerodynamic profile that diss
The advancement of mobile technologies and their ability to utilize the Global Positioning System (GPS) to accurately locate their substantial number of users, prompt Location-Based Services (LBS) significantly. Ride-sharing is a popular means of transportation that utilizes LBS. With the rapid development of smart cities and their impact on addressing the critical issues of urban life such as tra
Background: Reuse of sterile textiles could potentially reduce the carbon footprint of operating theatres. The aim of this mixed-methods study is to gain a deeper understanding of the implementation of reusable drapes and gowns across different contexts through applying the Consolidated Framework for Implementation Research (CFIR).Methods: A mixed-methods analysis was performed of cross-sectional
The Nature-Based Solutions (NbS) framework offers a promising pathway to address societal challenges such as food security, water management, and biodiversity loss, all under accelerating climate change. Aquatic ecosystems are central to addressing these challenges; however, their current implementation remains largely focused on isolated sites, limiting their effectiveness at landscape scales. He
Wild bees foraging in contemporary agricultural landscapes are, because of agricultural intensification, faced with the challenges of reduced flower-rich habitats, as well as a changed spatio-temporal distribution of flower resources. As a result of this and other stressors such as pesticide exposure, widespread declines of bees have been reported. However, all bees are not equally affected. To be
Highlights: Women predominantly exhibit HFpEF compared to men. Factors exclusive to women, such as adverse pregnancy outcomes and premature menopause, elevate the risk of HF. The establishment of sex-specific optimal drug dosages and concrete guidelines for device therapy is essential. Concerted multidisciplinary initiatives are crucial to bridge the existing sex disparities in HF management. Hear
The increasing depletion of fossil fuels, rising greenhouse gas emissions, and a growing global population have increased the need for sustainable food and energy sources. Traditional industrial biotechnology, which relies on plant-based feedstocks, competes with food production for arable land. In contrast, marine macroalgae do not require cultivatable land, irrigation by fresh water or fertilize
Cardiometabolic diseases are the leading preventable causes of death in most geographies. The causes, clinical presentations, and pathogenesis of cardiometabolic diseases vary greatly worldwide, as do the resources and strategies needed to prevent and treat them. Therefore, there is no single solution and health care should be optimised, if not to the individual (ie, personalised health care), the
Reduction in White Blood Cell, Neutrophil, and Red Blood Cell Counts Related to Sex, HLA, and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes Reduction in White Blood Cell, Neutrophil, and Red Blood Cell Counts Related to Sex, HLA, and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes Falastin Salami,1 Hye-Seung Lee,2 Eva Frey
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/92%2009102019_679_092_MP177_Salami_Diabetes_2018.pdf - 2026-10-19
