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The impact of amyloid-β (Aβ) accumulation on regional brain atrophy in preclinical Alzheimer’s disease (AD), and its interaction with risk factors like sex and APOE -ε4 carriership, remains unclear. In this study, we examined these associations in a population of older adults without dementia and evaluated the potential of Aβ-PET for risk stratification. We included 1329 participants (56 % female)
Highbush blueberry production has expanded worldwide in recent decades. To safeguard future yields, it is essential to understand if insect pollination is limiting current blueberry production and which insects contribute to pollination in different production regions. We present a systematic review including a set of meta-analyses on insect-mediated pollination in highbush blueberry. We summarize
Two groups of organisms dominate the decomposition in soil: fungi and bacteria. One of the most important parameters to optimise for any organism is its growth, and thus a direct way to study the effect of environmental factors on fungi and bacteria in soil is to measure their growth rate. However, methodological constraints have historically prevented this direct approach in soil. Using leucine/t
The incidence of cutaneous melanoma (CM) has risen sharply over the past 30 years, coinciding with the rapidly growing tattoo trend. In Sweden, 20% of the population is tattooed. Repeated reports of the presence of carcinogenic chemicals, such as polyaromatic hydrocarbons, aromatic amines and heavy metals in tattoo ink justifies the investigation of CM risk in relation to tattooing. We aimed to in
IMPORTANCE Diurnal fluctuations of motor and nonmotor symptoms and a high prevalence of sleep-wake disturbances in Parkinson disease (PD) suggest a role of the circadian system in the modulation of these symptoms. However, surprisingly little is known regarding circadian function in PD and whether circadian dysfunction is involved in the development of sleep-wake disturbances in PD. OBJECTIVE To d
Early-stage sustainable fashion enterprises face a structural paradox: they are increasingly expected by funders, investors, and programme partners to demonstrate measurable environmental performance, yet the ISO-compliant Life Cycle Assessment (LCA) that rigorous measurement demands is largely inaccessible to ventures operating with small teams, limited data infrastructure, and constrained budget
User Equipment (UE) grouping entails categorizing multiple UEs, including mobile phones or smart devices, according to defined criteria. It provides valuable insights for applications to optimize network resources, enhance handover procedures, and improve user experience. This study investigates UE grouping in a Fifth Generation (5G) Time Division Duplex (TDD) system based on Uplink (UL) Sounding
Sharks are an ecologically important group of fishes important to maintaining ecosystem structure and function, yet the additive effects of climate change and anthropogenic activities threaten their survival. Northwestern Atlantic populations of shortfin mako sharks and white sharks are considered threatened species, with populations in decline since the 1950s. Previous conservation efforts have a
Nationer och aktörer världen över har satt upp klimatmål och strategier för att minska på sina utsläpp av växthusgaser i kampen för att uppnå 1,5 gradersmålet i tid. Norconsult som är ett konsultföretag verksamma inom samhällsplanering och samhällsbyggnad är ett av många företag som satt upp interna mål om utsläppsreduktion för att minska på verksamhetens egen klimatpåverkan. Norconsult hoppas på Global authorities and businesses around the world have come up with a joint climate goal, including strategies to reduce greenhouse gas emissions in an effort to fight and reach the “1.5 degrees” goal in time. Norconsult, which is a consulting company that operates within social planning, and infrastructural design, is one of many modern companies that have initiated their own internal climate go
Title: The perceived innovativeness of the manufacturing process and perceived product quality. The case of creative and technology-intensive industries. Course: BUSN39 Degree Project in Global Marketing Authors: Federica Piccone & Joanna Pilawa Supervisor: Javier Cenamor Keywords: manufacturing process; perceived innovativeness; perceived quality Thesis Purpose: The main purpose is to
Problem: When opening a newspaper today there is a good chance that the headlines have something to do with recent developments in the global climate debate. This development is forcing companies to take action. The problem for many companies, including Thule, is that they are unaware of the environmental work conducted throughout their value chain and also what they need to do to become green. Th
In contrast to the peripheral role of mother tongue as a subject in Sweden, English has retained an elevated position. Together with Swedish, English is characterized as being crucial to Swedish society, positioning both languages at the top of the linguistic hierarchy. Given the generally perceived low status of mother tongue instruction (MTI) and high status of English in Sweden, an interesting
Eld är en av de viktigaste störningsprocesserna som påverkar den terrestra biosfären genom att forma vegetationens spridning, komposition, struktur, växtdiversitet och biokemiska cykler. Några av de mest påverkade ekosystemen är våt-torra områden, här klassificerade som savann eller Medelhavsområden. Denna påverkan kan studeras på olika sätt, antingen genom ett långvarigt och fortlöpande experimenFire is one of the most important disturbance processes affecting the terrestrial biosphere, altering the vegetation composition and distribution, structure, plant diversity and biogeochemical cycles. Some of the most influenced ecosystems are wet-dry areas, here classified as savannah or Mediterranean regions. The influence can be studied in different ways, either by long-term experiments like th
The main objective of this study is to investigate the environmental work progress in Sweden with a focus on buildings. Variety of actions as well as investment programs have come and gone, likewise the public and political commitment to the issue. Today, there is a common knowledge about how our human actions lead to a negative impact on the environment. We need more coordinated actions to revers
Background: Metastases from primary breast cancers can involve single or multiple organs at metastatic disease diagnosis. Molecular risk factors for particular patterns of metastastic spread in a clinical population are limited. Methods: A case-control design including 1357 primary breast cancers was used to study three distinct clinical patterns of metastasis, which occur within the first six mon
Type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD) often co-occur. Defining causal pathways underlying this relationship may help optimize the prevention and treatment of both diseases. Thus, we assessed the strength and magnitude of the putative causal pathways linking dysglycemia and fatty liver, using a combination of causal inference methods.Measures of glycemia, insulin dynam
PurposeThe purpose of this paper is to analyse the impact of six energy consumption factors (unsold products, product returns, packaging, freight transport, passenger transport and buildings) on the total energy consumption in three types of distribution channels for e-commerce and conventional trade.Design/methodology/approachThe study uses a quantitative calculation model where input data for th
Background: Most studies on synthetic computed tomography (sCT) generation for brain rely on in-house developed methods. They often focus on performance rather than clinical feasibility. Therefore, the aim of this work was to validate sCT images generated using a commercially available software, based on a convolutional neural network (CNN) algorithm, to enable MRI-only treatment planning for the
