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The past 23 years of post-socialist restructuring of health system funding and management patterns has brought many changes to small Balkan markets, putting them under increasing pressure to keep pace with advancing globalization. Socioeconomic inequalities in healthcare access are still growing across the region. This uneven development is marked by the substantial difficulties encountered by loc
The Port of Rotterdam is an important industrial cluster mainly comprising of oil refining, chemical manufacturing and power and steam generation. In 2015, the area accounted for 18 % of the Netherlands' total CO2 emissions. The Port of Rotterdam Authority is aware that the port's economy is heavily exposed to future global and EU decarbonization policies, as the bulk of its activities focuses on
Buildings are responsible for a third of global greenhouse gas emissions, with much of their life cycle impacts stemming from embodied impacts of building materials. Both at EU and Member State level, circular economy and resource efficiency policies are promoting production of lower-impact building materials with secondary material input. However, secondary material strategies do not result in ca
The consideration of local knowledge in assessments and governance of biodiversity and ecosystems is a vital challenge for a just and sustainable future. This requires in-depth consideration of the intricate ways people know, engage with and are affected by natural environments. However, the concept of local knowledge is fluid, and several interpretations are in use, which can complicate construct
Biocoal is a fossil- free reductant in metallurgical processes. Due to the increasing use, risks associated with self-heating needs to be better understood. In this work, the apparent activation energy and reaction kinetics of a commercial biocoal were investigated using isothermal calorimetry, differential scanning calorimetry, thermogravimetric analysis, and basket heating tests, including the c
Background: Emerging and re-emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods: A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to members of the International Society of Blood Transfusio
PURPOSE: This study aimed to describe the current management of patients with keratoconus in European and Middle Eastern countries through the collection of real-world data from clinicians actively managing keratoconus.METHODS: Computer-assisted web interviewing survey targeting ophthalmologists actively involved in collagen cross-linking (CXL) management. The questionnaire covered clinician demog
In these times, when global warming is escalating and the finite resources of the world are consumed in a fast pace, it is very important to find sustainable solutions for the near future. Transport is one of the sectors that need to find alternative solutions to the utilisation of fossil fuels. This master thesis investigates biogas production from ley crops, which is a mixture of different speci
Sustainable development “which meets the needs of the present without compromising the ability of future generations to meet their own needs,” (WCED 1987) is a global development objective of paramount importance. However, on the ground, ‘sustainable development’ is – in my experience – often little more than a buzzword for securing grants. From a strong sus-tainability standpoint, this thesis doc
Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas
Identifying concomitant Lewy body (LB) pathology through seed amplification assays (SAA) might enhance the diagnostic and prognostic work-up of Alzheimer’s disease (AD) in clinical practice and trials. This study examined whether LB pathology exacerbates AD-related disease progression in 795 cognitively impaired individuals (Mild Cognitive Impairment and dementia) from the longitudinal multi-cente
Therapies against cell-surface targets (CSTs) represent an emerging treatment class in solid malignancies. However, high-throughput investigations of CST expression across cancer types have been reliant on data sets of mostly primary tumors, despite therapeutic use most commonly in metastatic disease. We identified a total of 818 clinical trials of CST therapies with 78 CSTs. We assembled a data s
Selecting the most suitable procurement strategy is crucial to the efficient management of supply chain operations and the prevention of stock shortages. Nevertheless, when dealing with a wide variety of products, this task becomes an intricate challenge. While traditional and advanced procurement tools are available, applying them across such diverse product ranges is often impractical. This rese
The European Union has committed to achieving climate neutrality by the year 2050, with Sweden setting an even more ambitious target of reaching this milestone by 2045. A subgroup comprising 23 pioneering Swedish municipalities, collectively representing 40% of the country's population, aims to attain climate neutrality by 2030. Globally, buildings and construction sector contribute nearly 40% of
Family accommodation (FA) is widely-recognised as an important clinical phenomenon in obsessive–compulsive disorder (OCD) and anxiety disorders, and is related to poorer treatment outcomes. However, FA has not been quantitatively explored in Body Dysmorphic Disorder (BDD). The aim of this study was to investigate the patterns and correlates of maternal accommodation in adolescent BDD, and its asso
While the associations of mid-life cardiovascular risk factors with late-life white matter lesions (WMH) and cognitive decline have been established, the role of cerebral haemodynamics is unclear. We investigated the relation of late-life (69–71 years) arterial spin labelling (ASL) MRI-derived cerebral blood flow (CBF) with life-course cardiovascular risk factors (36–71 years) and late-life white
Humanity has long battled mosquitoes and the diseases they transmit—a struggle intensified by climate change and globalization, which have expanded mosquito ranges and the spread of associated diseases.1 Additionally, widespread insecticide resistance has reduced the efficacy of current control methods, necessitating new solutions.2,3 Nootkatone, a natural compound found in grapefruit, shows promi
Speckle metrology is a powerful optical sensing tool for non-destructive testing (NDT) and advanced surface characterization, enabling ultra-precise measurements of surface deformations and displacements. These capabilities are critical for material analysis and surface assessment in sensing-driven applications. However, traditional correlation methods often struggle to balance resolution and robu
This white paper presents a comprehensive biobanking framework developed at the European Cancer Moonshot Lund Center that merges rigorous sample handling, advanced automation, and multi-omic analyses to accelerate precision oncology. Tumor and blood-based workflows, supported by automated fractionation systems and standardized protocols, ensure the collection of high-quality biospecimens suitable
Icy dust particles emerge in star-forming clouds and are subsequently incorporated in protoplanetary disks, where they coagulate into larger pebbles up to millimeter in size. In the disk midplane, ices are shielded from UV radiation, but moderate levels of disk turbulence can lift small particles to the disk surface, where they can be altered, or destroyed. Nevertheless, studies of comets and mete
