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REMO-HAM is a new regional aerosol-climate model. It is based on the REMO regional climate model and includes most of the major aerosol processes. The structure for aerosol is similar to the global aerosol-climate model ECHAM5-HAM, for example the aerosol module HAM is coupled with a two-moment stratiform cloud scheme. On the other hand, REMO-HAM does not include an online coupled aerosol-radiatio
Some foreign policy analysts believe that what we are witnessing in the 21st century is nothing short of a reconfiguring of the global political order - with China firmly positioned at the helm as a (re)emerging great power. At present, the notion of the imminent establishment of a ‘new world order with Chinese characteristics’ is increasingly gaining traction. This sentiment has long permeated fo
BACKGROUND: Insulin resistance (IR) in skeletal muscle is a key feature of the pre-diabetic state, hypertension, dyslipidemia, cardiovascular diseases and also predicts type 2 diabetes. However, the underlying molecular mechanisms are still poorly understood.METHODS: To explore these mechanisms, we related global skeletal muscle gene expression profiling of 38 non-diabetic men to a surrogate measu
The ongoing COVID-19 pandemic has radically changed the way we live and had an enormous impact on the global healthcare system [ [1]]. Among many restrictions imposed on the societies, the national lockdowns have particularly disrupted the natural social networks and forced citizens to involuntary isolation. As a result, many patients have felt discouraged to visit their doctors, while emergency d
Improvement of structural efficiency in various materials is critically important for sustainable society development and the efficient use of natural resources. Recently, a lot of attention in science and engineering has been attracted to heterogeneous-structure materials because of high structural efficiency. However, strategies for the efficient design of heterogenous structures are still in th
Purpose – The 2004 Boxing Day tsunami prompted global efforts to develop end-to-end multi-hazard warning systems. Taking this event as a starting point, and drawing on experiences from the following advancement of the Indonesian tsunami early warning system, this paper aims to highlight the importance of paying attention to human factors and the perceptions and behaviors of end recipients when try
The use of radio signal for position tracking (positioning) and navigation has a long tradition. Most notably, global navigation satellite systems (GNSS) are now widely applied for civilian applications, ranging all the way from tracking of cargo containers to gaming. However, GNSS suffers from limited coverage in dense urban areas and indoors and also from a limited position accuracy, which rules
The African continent is facing one of the driest periods in the past three decades as well as continued deforestation. These disturbances threaten vegetation carbon (C) stocks and highlight the need for improved capabilities of monitoring large-scale aboveground carbon stock dynamics. Here we use a satellite dataset based on vegetation optical depth derived from low-frequency passive microwaves (
Energy intensive industries (EIIs), producing the basic materials and products needed in society, contribute significantly to global emissions of greenhouse gases (GHGs). Motivated by the fear of carbon leakage, climate policy has so far treated the EIIs leniently with e.g. low carbon prices and/or free allocation of emission allowances. This has not resulted in more than marginal emission abatemeEnergy intensive industries (EIIs), producing the basic materials and products needed in society, contributesignificantly to global emissions of greenhouse gases (GHGs). Motivated by the fear of carbon leakage, climatepolicy has so far treated the EIIs leniently with e.g. low carbon prices and/or free allocation of emissionallowances. This has not resulted in more than marginal emission abatement.
Background: Fitness costs imposed on bacteria by antibiotic resistance mechanisms are believed to hamper their dissemination. The scale of these costs is highly variable. Some, including resistance of Staphylococcus aureus to the clinically important antibiotic mupirocin, have been reported as being cost-free, which suggests that there are few barriers preventing their global spread. However, this
Apolipoprotein (APOE) ε4 is a major genetic risk factor for Alzheimer's disease (AD), but its importance for the clinical and biological heterogeneity in AD is unclear, particularly at the prodromal stage. We analyzed 151 prodromal AD patients (44 APOE ε4-negative and 107 APOE ε4-positive) from the BioFINDER study. We tested cognition, 18F-flutemetamol β-amyloid (Aβ) positron emission tomography,
The aim of this paper is to critically examine, discuss, draw conclusions, and come up with ideas how to harmonize GIS education in order to realize the envisaged clientele benefits globally. The paper draws experiences and lessons learnt, with examples from ongoing joint GIS MSc programs/courses being implemented in Mozambique, Rwanda, and Uganda. All the five courses (3 in Uganda, 1 in Mozambiqu
Multipotent progenitor cells confirm their T cell–lineage identity in the CD4–CD8– double-negative (DN) pro-T cell DN2 stages, when expression of the essential transcription factor Bcl11b begins. In vivo and in vitro stage-specific deletions globally identified Bcl11b-controlled target genes in pro-T cells. Proteomics analysis revealed that Bcl11b associated with multiple cofactors and that its di
This article explores the paradox of corporations using social and environmental justice concerns to market products that are themselves made in conditions of environmental and social injustice, most often in the Global South. The effects of the fashion industry on people is two-pronged: 1) the unsafe and exploitative conditions under which many garment workers operate, and 2) the severe and harmf
Large-scale science research facilities, such as those for investigation into the smallest components of physical matter, often consist of buildings with quite extraordinary features as regards shape and scale. These architectures are semiotically interesting in several ways: they have extraordinary outer forms that reflect the their inner activities; they require forms of mediation and planning t
With the increased concern about energy security, air pollution and global warming, the possibility of using polymer electrolyte fuel cells (PEFCs) in future sustainable and renewable energy systems has achieved considerable momentum. A computational fluid dynamic model describing a straight channel, relevant for water removal inside a PEFC, is devised. A volume of fluid (VOF) approach is employed
Germany has one of the most ambitious climate policy goals worldwide, having pledged to reduce national emissions by 40% by 2020, and 80–95% by 2050 (base year: 1990). 2015 data suggests that progress on decarbonisation has slowed, also because emissions from the transport sector have grown. Road transport, which is contributing 20.5% to Germany's CO2 emissions, has become a major obstacle to achi
ABSTRACT: In the light of the observed and projected regional warming trend in northern Europe, new recommendations are needed for climate-proofing the selection of forest trees seedlings and growth estimates. Drawing on recently developed climate data sets, both observations of the recent past, and scenarios for the future we present and analyse a set of climate indices tailored to be used for op
