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Macaca nemestrina, which may have larger and more numerous pancreatic islets than other species, was used for large scale islet isolation by ductal collagenase perfusion and Ficoll gradient centrifugation. The average yield was 51,000 islet equivalents per pancreas, or 8,750 islets equivalents per g. The average purity was 91%, often exceeding 95%. These are the highest reported size, purity, and
The concentrations of gamma-trace and beta2-microglobulin in cerebrospinal fluid (CSF) and plasma were determined in 64 individuals of various ages without signs of organic disorder in the central nervous system (CNS). A strong connection was found between the CSF level of gamma-trace and the age of the individual, with the CSF level of newborns being 3--4 times that of adults. A similar, but less
OBJECTIVE: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients' psychosocial status and quality of life compared with healthy participants.METHODS: In 37 patients with intraorally or extraorally presenting trigeminal nerve damage diagnosed as painful or nonpainful posttraumatic t
Substitution of IgG in antibody deficiency or application of high-dose intravenous IgG (IVIg) in patients with autoimmunity are well-established treatments. Data on the mode of action of IVIg are, however, controversial and may differ for distinct diseases. In this study, we investigated the impact and molecular mechanism of high-dose IgG treatment in murine autoantibody-induced skin inflammation,
BACKGROUND AND PURPOSE: The aim of this study was to analyze a magnetic resonance imaging (MRI)-only radiotherapy workflow from an economic perspective in terms of reduced time, costs and systematic uncertainties.MATERIAL/METHODS: A documented Swedish clinical implementation of MRI-only radiotherapy was used as template for cost assessments compared to a combined computed tomography (CT)/MRI workf
Myeloproliferative neoplasms (MPNs) are blood cancers that are characterized by the excessive production of mature myeloid cells and arise from the acquisition of somatic driver mutations in haematopoietic stem cells (HSCs). Epidemiological studies indicate a substantial heritable component of MPNs that is among the highest known for cancers1. However, only a limited number of genetic risk loci ha
Heparan sulfate proteoglycans consist of a small family of proteins decorated with one or more covalently attached heparan sulfate glycosaminoglycan chains. These chains have intricate structural patterns based on the position of sulfate groups and uronic acid epimers, which dictate their ability to engage a large repertoire of heparan sulfate-binding proteins, including extracellular matrix prote
BACKGROUND: Patients presenting with peritoneal metastases (PM) of colorectal cancer (CRC) can be curatively treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Angiogenesis is under control of multiple molecules of which HIF1a, SDF1, CXCR4, and VEGF are key players. We investigated these angiogenesis-related markers and their prognostic value in patient
OBJECTIVE: The late revelation of ovarian cancer ensures it as the leading cause of death among gynecologic cancers. Cytoreductive surgery (CRS) and intravenous (i.v.) chemotherapy have been the cornerstone for a long time to treat this disease. More recently, the modality of intraperitoneal administration of chemotherapy under hyperthermic conditions (HIPEC) has been added. This review surveys th
OBJECTIVE: The purpose was to test the hypothesis that the HLA-DQαβ heterodimer structure is related to the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: Next-generation targeted sequencing was used to genotype HLA-DQA1-B1 class II genes in 670 subjects in the Diabetes Prevention Trial-Type 1 (DPT-1). Coding sequences were tra
PURPOSE: Distal ulnar Hounsfield unit (HU) measurements obtained from computed tomography (CT) scans of the wrist can be used to accurately screen for low bone mineral density. It is unknown whether HU measurements can also predict the risk of future fragility fractures. Therefore, the purpose of this study was to determine if the HU values of the distal ulna correlate to fragility fracture risk.M
The diphtheria toxin-like ADP-ribosyltransferases (ARTDs) are an enzyme family that catalyzes the transfer of ADP-ribose units onto substrate proteins by using nicotinamide adenine dinucleotide (NAD(+)) as a cosubstrate. They have a documented role in chromatin remodelling and DNA repair, and inhibitors of ARTD1 and 2 (PARP1 and 2) are currently in clinical trials for the treatment of cancer. The
Monoclonal gammopathy of undetermined significance (MGUS) is the precursor of multiple myeloma (MM) and related disorders. MGUS is characterized by asymptomatic paraproteinemia. In some cases, multiple paraproteins can be identified but the clinical implications of this phenomenon are poorly understood. In this study, we aim to inform the approach to this challenging MGUS subgroup by utilizing dat
Background: The debate over legalizing medical assistance in dying (assisted dying) is ongoing, also in Nordic countries such as Sweden where assisted dying is illegal. A 2020 survey by the Swedish Medical Association highlighted varied perspectives, with 41% of physicians supporting and 34% opposing legalization. Professionals in palliative care were more negative toward it. Objective:
PM för kurs 14 2019-02-19 PM för kurs 14 Examensarbete för psykologexamen Margit Wångby-Lundh KURSANSVARIG 2 Innehåll Kurs 14 ...........................................................................................................4 Kursens mål ...................................................................................................4 Kunskap och förståelse .............................
https://www.psy.lu.se/sites/psy.lu.se/files/pm_for_kurs_14_vt19_-_190219.pdf - 2026-08-01
+0100 Sancit Marci Euangelium Kurztitel Mar26S Titel Sancti Marci Euangelium Entstehungszeit 1526 Textsorte Bibeltext Umfang 14.187 Bearbeitungsstand abgeschlossen; KF, 09.01.2006 Bemerkungen Blattzahlen aus Faksimileausgabe durch z.B. 23 a und 23b gekennzeichnet; aufgelöste Kürzel durch Kursiv gekennzeichnet [‡‡ 22a] [Sancti Marci Euangelium.] Första Capitel. Thetta är begynnilsen aff Jesu Christ
https://www.nordlund.lu.se/fileadmin/user_upload/fornsvenska/rtf/Mar26SLundversion.rtf - 2026-07-24
ISL B37 Litteraturlista Humaniora och teo log i Centrum fö r teo log i och re l ig ionsvetenskap Litteraturlista för ISL B37 Islamologi: Uppsatskurs, 7,5 hp, VT 2026 fastställd av studierektor 2025-12-08 Böcker Björklund, Maria & Ulf Paulsson (2012). Seminarieboken: Att skriva, presentera och opponera. Lund: Studentlitteratur. ISBN 978-91-44-05985-3. Watt, Montgomery W. (2008). Islamic Philosophy
https://www.ctr.lu.se/media/utbildning/dokument/kurser/ISLB37/20261/ISL_B37_Litteraturlista.pdf - 2026-07-31
Marcus GladerInnovation Markets and Competition Analysis- EU competition law and US antitrust lawDatum för disputation: lördagen den 11 december 2004Fakultetsopponent: senior visiting research fellow John Temple, Oxford universitet, EnglandÄmne: civilrättAbstractInnovation issues are increasingly highlighted in public policy, including competition policy. Not only is innovation a major factor behi
https://www.jur.lu.se/forskning/disputationer/disputationer-2004 - 2026-07-31
