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Popular Abstract in Swedish Lipasadsorption till fasta ytor studerades med hjälp av in situ ellipsometri. Samtidigt mättes aktiviteten av det adsorberade lipaset in situ genom hydrolys av p-nitrofenylacetat. Adsorption mättes till metylerade kiseloxidytor med varierande grad av metylering samt till rent kiseloxid. Olika lipaser studerades; lipas från Humicola lanuginosa (HLL)­vildtypen (WT) och enThe adsorption of lipases to solid surfaces was studied by means of in situ ellipsometry. In addition, the activities of the adsorbed lipases were measured in situ, by the hydrolysis of p-nitro phenyl acetate. Adsorption was made to methylated silica surfaces with varying degree of wettability as well as to clean silica surfaces. Lipases from Humicola lanuginosa (HLL) ­ the wild-type (WT) and a m

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Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in b

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Popular Abstract in Swedish Vår hud och våra slemhinnor är ständigt koloniserade med bakterier som lever i fredligt samspel med vår organism. Dessa bakterier tillhör vår normalflora och kan indelas i kommensaler respektive opportunistiska bakterier. Kommensalerna gagnar värden på olika sätt och orsakar inte sjukdom, till skillnad från opportunisterna som under vissa betingelser kan orsaka infektioAbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and protein, forming organized communities called biofilms. In the biofilm bacteria are protected against hostile environments. Biofilms are important clinically because of their persistence despite host defence and their recalcitrance to antimicrobials. This thesis presents three main findings: (i) biof

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Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide association studies (GWAS). This meta-analysis combines 11 GWAS (5 previously unpublished) and a further three stage 2 data sets, totaling 15,990 CMM cases and 26,409 controls. Five loci not previously asso

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1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav