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A 37-year-old man sustained occlusion of the right coronary artery after a bicycle accident with blunt chest trauma over the left scapula. Acute coronary angiography was performed because of chest pain and ST-segment elevation. Despite surgically successful acute revascularization the patient developed a transmural inferior wall infarction. Coronary artery occlusion after blunt chest trauma is rar

Somatic mosaicism, the presence of genetically distinct cells within an organism, has been increasingly associated with human morbidity, ranging from being a cause of rare syndromes to a risk factor for common disorders such as malignancy and cardiovascular disease. Previous studies interrogating the normal prevalence of somatic mosaicism have focused on adults. We here present an estimate of the

Abstract: Animal models of Parkinson's disease (PD) are important for understanding the mechanisms of the disease and can contribute to developing and validating novel therapeutics. Ideally, these models should replicate the cardinal features of PD, such as progressive neurodegeneration of catecholaminergic neurons and motor defects. Many current PD models emphasize pathological forms of α-synucle

Human lactoferrin is an iron-binding glycoprotein that is particularly prominent in exocrine secretions and leukocytes and is also found in serum, especially during inflammation. It is able to sequester iron from microbes and has immunomodulatory functions, including inhibition of both complement activation and cytokine production. This study used mutants lacking pneumococcal surface protein A (Ps

In preclinical research, allergic asthma is investigated in rats sensitised with the antigen ovalbumin (OVA), followed by a challenge with aerosolised OVA to induce an inflammatory reaction of the lower airways. This causes diffuse, nonfocal ventilation defects that lead to heterogeneously distributed signal intensities in hyperpolarised (HP) (3)He MR images, which are difficult to assess directly

Laser-induced fluorescence (LIF) was used to characterise the localisation of an intravenously administered trimethylated carotenoporphyrin [CP(Me)(3)] and a trimethoxylated carotenoporphyrin [CP(OMe)(3)] in an intramuscularly transplanted malignant tumour (MS-2 fibrosarcoma) and healthy muscle in female Balb/c mice, 3, 24, 48 and 96 h post injection. The fluorescence was induced with a dye laser

Clin Microbiol InfectAbstract Propionibacterium acnes is a common and probably underestimated cause of delayed joint prosthesis infection. Bacterial biofilm formation is central in the pathogenesis of infections related to foreign material, and P. acnes has been shown to form biofilm both in vitro and in vivo. Here, biofilm formation by 93 P. acnes isolates, either from invasive infections (n = 45

Aims  In a cohort of men and women with Type 1 diabetes, prospectively followed for > 20 years, vibrotactile sense in fingers was investigated and related to neurophysiological tests, glycaemic level and clinical score. Methods  Out of 58 patients, diagnosed at the age of 15-25 years and recruited 1984-1985, 32 patients (13 women, median age 52 years, range 44-75 years; 19 men, median age 52 years

Atypical hemolytic uremic syndrome has been associated with dysregulation of the alternative complement pathway. In this study, a novel heterozygous C3 mutation was identified in a factor B-binding region in exon 41, V1636A (4973 T > C). The mutation was found in three family members affected with late-onset atypical hemolytic uremic syndrome and symptoms of glomerulonephritis. All three patients

The growth-promoting polyamines are polybasic compounds that efficiently enter cancer cells by as yet incompletely defined mechanisms. Strategies to inhibit their internalization may have important implications in the management of tumor disease. Here, we show that cellular binding and uptake of polyamines are inhibited by a single chain variable fragment anti-heparan sulfate (HS) antibody. Polyam

A noncompetitive flow immunoassay system (FIA) for the analysis of interleukin-8 (IL-8) in cell samples was developed. Affinity interaction assays based on offline incubation of excess labeled antibodies and antigen (IL-8) were carried out. The residual unbound labeled antibody was trapped in an immunoaffinity column with immobilized IL-8 while the immunocomplex, labeled antibody/IL-8, was detecte

Rationale: Mechanisms underlying vasomotor abnormalities and increased peripheral resistance exacerbating heart failure (HF) are poorly understood. Objective: To explore the role and molecular basis of myogenic responses in HF. Methods and Results: 10 weeks old C57Bl6 mice underwent experimental myocardial infarction (MI) or sham surgery. At 1 to 12 weeks postoperative, mice underwent hemodynamic

This paper presents diagnostic criteria for Menière’s disease jointly formulated by the Classification Committee of the Bárány Society, The Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the Equilibrium Committee of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society. The classification includes two

Syftet är att beskriva och analysera hur ett kundrelationsperspektiv kan förbättra kunskapsintensiva organisationer. Frågeställningen är följande: Hur kan kundrelationsperspektivet förbättra förvaltandet av kunskap inom kunskapsintensiva organisationer? För att ta reda på detta utgår vi från Relationsmarknadsföringsteorier. De aspekter och centrala begrepp ur tankegångarna kring kundrelationer som

The fatty acid compositions of forty-five strains of anaerobic curved rods isolated from vaginal content were analysed by gas chromatography. Twenty-six of the strains were of a short Gram-variable type and 19 of a long Gram-negative type. The bacteria were subjected to alkaline saponification, after which the liberated fatty acids were methylated using boron trichloride-methanol. The samples were

The iron-chromium (Fe/Cr) catalyst is used for high-temperature water-gas shift (HT WGS) reaction. A major concern using the Fe/Cr catalyst is that it contains hexavalent chromium (Cr+6) which is a potent carcinogen causing health and environmental issues. In order to reduce the usage of chromium in industrial HT WGS applications, a chromium-free catalyst needs to be developed. The aim of this the

Nyhetsbrev_2023-2.pub NYTT FRÅN SACO Sommarhälsning från Saco! Sacos styrelse önskar alla medlemmar en riktigt skön och ledig sommar! Sommaruppehåll Samtliga fack samt SLU har enats om att ha ett uppehåll under sommaren. Under tiden mellan 5 juli - 14 augusti har vi inga MBL förhandlingar oavsett vilka ärenden det gäller. Men givetvis har personalavdel- ningen alltid någon som går att nå och det g

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/slu/nyhetsbrev/nyhetsbrev_2023-2.pdf - 2026-09-18