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With their superficially shark-like appearance, the Mesozoic ichthyosaurs provide a classic illustration of major morphological adaptations in an ancestrally terrestrial tetrapod lineage following the invasion of marine habitats1, 2–3. Much of what is known about ichthyosaur soft tissues derives from specimens with body outlines4, 5–6. However, despite offering insights into aspects of biology tha

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Purpose: The mean diffusivity (MD) is sensitive to the microstructure of the cortex. However, partial volume effects with CSF and white matter (WM) may obscure pathology-related alterations. This work investigates both existing approaches and a novel approach for reducing partial volume effects. Theory and Methods: A bias in MD arises due to partial volume effects, higher-order terms, and the nois

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We simulate interactions between adsorbing and nonadsorbing surfaces immersed in solutions containing monodisperse semiflexible chains. Apart from the nature of the surfaces, we investigate responses to changes of the intrinsic chain stiffness, the degree of polymerization, and the bulk concentration. Our simulations display a sufficient accuracy and precision to reveal free-energy barriers that a

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We introduce four-point functions in the hadronic ladder resummation approach to large N-c QCD Green functions. We determine the relevant one to calculate the B-K kaon parameter in the chiral limit. This four-point function contains both the large momenta QCD OPE and the small momenta ChPT at NLO limits, analytically. We get (B) over cap (X)(K) = 0.38 +/- 0.15. We also give the ChPT result at NLO

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Mixtures of carboxymethyl cellulose (CMC) or hydrophobically modified CMC with an oppositely charged surfactant (benzyldimethyltetradecylammonium chloride) in water were prepared. When the global polymer concentration is 0.18% by weight and the surfactant content is high enough, a precipitate with hexagonal order is formed. The precipitate composition shows practically constancy in its water conte

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BACKGROUND: Adolescent smokers are often unsuccessful in quitting and difficult to retain in cessation programs. In health promotion, focusing on the right target groups is essential. Aim. The aim was to examine if adolescent occasional smokers differ from daily smokers, and if possible differences could be useful for targeted smoking cessation programs. METHODS: Ninety-one percent of all teenager

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Estramustine (EM), a complex between estradiol-17 beta and nornitrogen mustard, is commonly used in the treatment of prostatic cancer. The exact mechanism of action is unknown but has previously been considered to be mediated through non-DNA targets, specifically with the mitotic spindle, and to be related to the intact EM complex. In the present study, using different cell-systems (monocyte phago

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This paper examines whether the higher wages paid by foreign-owned manufacturing plants than by domestically owned plants, typical of most countries, represents a higher price for labor. That is, does it reflect a higher price for workers of a given quality, as represented by the level of education? We then ask whether foreign-owned plants pay a higher price for labor given the characteristics of

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Carbon storage dynamics in vegetation and soil are determined by the balance of carbon influx and turnover. Estimates of these opposing fluxes differ markedly among different empirical datasets and models leading to uncertainty and divergent trends. To trace the origin of such discrepancies through time and across major biomes and climatic regions, we used a model-data fusion framework. The framew

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Quantum mechanical weak values of projection operators have been used to answer which-way questions, e.g. to trace which arms in a multiple Mach–Zehnder setup a particle may have traversed from a given initial to a prescribed final state. I show that this procedure might lead to logical inconsistencies in the sense that different methods used to answer composite questions, like “Has the particle t

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The discrete circle map is the archetypical example of a driven periodic system, showing a complex resonance structure under a change of the forcing frequency known as the devil's staircase. Adler's equation can be seen as the direct continuous equivalent of the circle map, describing locking effects in periodic systems with continuous forcing. This type of locking produces a single fundamental re

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We propose a phenomenological model for the polygonal hydraulic jumps discovered by Ellegaard and co-workers, based on the known flow structure for the type-II hydraulic jumps with a "roller" (separation eddy) near the free surface in the jump region. The model consists of mass conservation and radial force balance between hydrostatic pressure and viscous stresses on the roller surface. In additio

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To investigate the effects of changes in biopolymer composition on moisture in acetylated poplar wood (Populus euramericana Cv.), the acetylation of control wood was compared to the acetylation of wood with reduced hemicellulose or lignin content (about 9% reduction of total specimen dry weight in both cases). Time-domain nuclear magnetic resonance relaxometry of water-saturated wood gave spin–spi

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In this paper different approaches to groundwater flow and its effect in the vicinity of a borehole ground heat exchanger are discussed. The common assumption that groundwater flow in hard rock may be modelled as a homogeneous flow in a medium with an effective porosity is confronted and models for heat transfer due to groundwater flow in fractures and fracture zones are presented especially from

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The behavior of poly-gamma-methyl-L-glutamate (pMeE) at the air-water interface has been studied with the surface film balance technique. In addition, Langmuir-Blodgett (LB) films of pMeE deposited on mica and quartz have been studied by atomic force microscopy (AFM) and circular and linear dichroism (CD and LD) spectroscopy. Depending on the spreading solvent, pMeE displays strikingly different c

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The efficacy and safety of high-dose intravenous polyspecific immunoglobulin G (IVIG) as adjunctive therapy in streptococcal toxic shock syndrome (STSS) were evaluated in a multicenter, randomized, double-blind, placebo-controlled trial. The trial was prematurely terminated because of slow patient recruitment, and results were obtained from 21 enrolled patients (10 IVIG recipients and 11 placebo r

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The CCSD(T) method has been used to compute a highly accurate quartic force field and fundamental frequencies for all 16O and 18O isotopomers of the ozonide anion. The CCSD and CASPT2 methods have also been used to verify the reliability of the CCSD(T) fundamental frequencies. The computed fundamental frequencies are in agreement with gas-phase experiments, but disagree with matrix isolation exper