Filetype
OBJECTIVE: To investigate markers of endothelial activation in muscle biopsies from rheumatoid arthritis (RA) patients with and without extra-articular manifestations (ExRA). PATIENTS AND METHODS: Nine consecutive ExRA patients were compared with nine RA controls without ExRA, matched for age, sex and duration of RA. Muscle biopsies were obtained from the lateral vastus or anterior tibial muscle.
The objective of this study was to examine the possibility of measuring the growth of three white-rot fungi in soil contaminated with polycyclic aromatic hydrocarbons (PAHs), by estimating the soil levels of the phospholipid fatty acid (PLFA) 18:2ω6,9. The effect of the fungi on the PAH concentration and on the indigenous bacterial population in the soil was monitored. As shown by visual examinati
Postmenopausal overweight women have an increased risk of breast cancer. The link between obesity and breast cancer could be mediated through hyperinsulinemia. Insulin and insulin-like growth factor-1 (IGF-1) stimulate mammary cell proliferation in vitro, and cell proliferation is directly linked to the risk of breast cancer. Our objective was to investigate the relationship between breast cancer
A Swedish non-word repetition test for preschool children was constructed with the aim of measuring short-term phonological memory, which has been shown to correlate with language development and language proficiency. Normative data based on results for 200 children four to six years of age are presented. An item analysis of the original 30-item test resulted in a shortened 24 non-word version fou
Treatment of [(mu-H)Os-3(CO)(10)(mu-OMe)] (1) with dppm {dppm = bis(diphenylphosphino)methane} at 110 degrees C gave the known compound [Os-3(CO)(10)(mu(2)-eta(2)-dppm)] (2) and the new compound [(mu-H)Os-3(CO)(8)(mu-OMe)(mu(2)-eta(2)-dppm)] (3). A similar reaction of 1 with dppe {dppe=bis(diphenylphosphino)ethane} afforded two products, [(mu-H)Os-3(CO)(8)(mu-OMe)(mu(1)-eta(2)-dppe)] (5) and [(mu-
Social phobia is one of the most frequent mental disorders and is accessible to two forms of scientifically validated treatments: anti-depressant drugs and cognitive behavior therapies (CBT). In this last case, graded exposure to feared social situations is one of the fundamental therapeutic ingredients. Virtual reality technologies are an interesting alternative to the standard exposure in social
Uppkomsten av NOSAM har sin grund i att dagens moderna samhällsutveckling mer eller mindre tvingar regioner att samarbeta för att stärka sin attraktionskraft gentemot omvärlden. Helt enkelt en ökad konkurrens. NOSAM innefattar ett regionalt område med tio olika medlemskommuner och befinner sig i en region som under de senaste 15 åren, mycket på grund av brobygget, genomgått en rad förändringar. Fö
Structural properties of encapsidated flexible polyelectrolytes in viral capsids with dodecahedral charge distribution have been investigated by Monte Carlo simulations using a coarse-grained model. Several capsid charge distributions ranging from a homogeneous surface charge distribution (lambda=0) to a complete dodecahedral distribution (lambda=1) at constant total capsid charge and fixed radial
Airway reactivity to bronchoconstrictor mediators changes with age. We studied the effects of maturational change on airway responses induced by a thromboxane A2 mimetic, U-46619 (2, 6 and 20 nmol/kg; i.v.), leukotriene D4 (0.6 and 2 nmol/kg; i.v.) or vehicle (0.9% NaCl; i.v.) in immature (196 +/- 3 g: 2 weeks) and adult guinea pigs (512 +/- 5 g: 11 weeks). In the same animals, we measured both lu
Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived
We simulate interactions between adsorbing and nonadsorbing surfaces immersed in solutions containing monodisperse semiflexible chains. Apart from the nature of the surfaces, we investigate responses to changes of the intrinsic chain stiffness, the degree of polymerization, and the bulk concentration. Our simulations display a sufficient accuracy and precision to reveal free-energy barriers that a
Intraspecific brood parasites lay their eggs in the nests of conspecifics. There are a number of methods for detecting intraspecific brood parasitism (IBP) in birds based on egg morphology. Here we test Eadie's (1989) method, which calculates the Euclidean distances between eggs in a given clutch in a three-dimensional space (weight, length and width). A parasitised clutch is predicted to contain
Cell adhesion molecules (CAMs) mediate cell attachment and stress transfer through extracellular domains. Here we forcibly unfold the Ig domains of a prototypical Ig superfamily CAM that contains intradomain disulfide bonds. The Ig domains of all such CAMs have conformations homologous to cadherin extracellular domains, titin Ig-type domains, and fibronectin type-III (FNIII) domains. Atomic force
In order to elucidate the composition of the female sex pheromone of the northern (beech) winter moth, Operophtera fagata Scharf. (Lepidoptera: Geometridae), ovipositor extracts of unmated, calling females were analysed by gas chromatography with simultaneous electroantennographic and flame ionization detection (GC-EAD/FID). Male antennal responses indicated three active components, two of which h
Several different methods were used to investigate the vesicle-to-micelle transition induced by the addition of the nonionic surfactant octaethylene glycol n-dodecyl monoether (C12E8) to spontaneously formed vesicle dispersions of dioctadecyldimethylammonium bromide and chloride (DODAX, X = Cl- and Br-). Dynamic light scattering reveals that fast mode micelles are formed upon addition of C12E6. Th
Arabidopsis thaliana has two isoforms of alpha-glycan phosphorylase (EC 2.4.1.1), one residing in the plastid and the other in the cytosol. The cytosolic phosphorylase, PHS2, acts on soluble heteroglycans that constitute a part of the carbohydrate pool in a plant. This study aimed to define a physiological role for PHS2. Under standard growth conditions phs2 knock-out mutants do not show any clear
When DNA molecules are heated they denature. This occurs locally so that loops of molten single DNA strands form, connected by intact double-stranded DNA pieces. The properties of this "melting" transition have been intensively investigated. Recently there has been a surge of interest in this question, in part caused by experiments determining the properties of partially bound DNA confined to nano
