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Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

Multiple myeloma (MM) is a plasma cell malignancy with a significant heritable basis. Genome-wide association studies have transformed our understanding of MM predisposition, but individual studies have had limited power to discover risk loci. Here we perform a meta-analysis of these GWAS, add a new GWAS and perform replication analyses resulting in 9,866 cases and 239,188 controls. We confirm all

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

A recent comprehensive whole genome analysis of a large breast cancer cohort was used to link known and novel drivers and substitution signatures to the transcriptome of 266 cases. Here, we validate that subtype-specific aberrations show concordant expression changes for, for example, TP53, PIK3CA, PTEN, CCND1 and CDH1. We find that CCND3 expression levels do not correlate with amplification, whil

Non-bee insects are important contributors to global crop pollination.

Wild and managed bees are well documented as effective pollinators of global crops of economic importance. However, the contributions by pollinators other than bees have been little explored despite their potential to contribute to crop production and stability in the face of environmental change. Non-bee pollinators include flies, beetles, moths, butterflies, wasps, ants, birds, and bats, among o

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer.

Whilst common genetic variation in many non-coding genomic regulatory regions are known to impart risk of colorectal cancer (CRC), much of the heritability of CRC remains unexplained. To examine the role of recurrent coding sequence variation in CRC aetiology, we genotyped 12,638 CRCs cases and 29,045 controls from six European populations. Single-variant analysis identified a coding variant (rs31

Cervical carcinoma and sexual behavior: collaborative reanalysis of individual data on 15,461 women with cervical carcinoma and 29,164 women without cervical carcinoma from 21 epidemiological studies

High-risk human papillomavirus (HPV) types cause most cervical carcinomas and are sexually transmitted. Sexual behavior therefore affects HPV exposure and its cancer sequelae. The International Collaboration of Epidemiological Studies of Cervical Cancer has combined data on lifetime number of sexual partners and age at first sexual intercourse from 21 studies, or groups of studies, including 10,77

Population genomics of Bronze Age Eurasia

The Bronze Age of Eurasia (around 3000-1000 BC) was a period of major cultural changes. However, there is debate about whether these changes resulted from the circulation of ideas or from human migrations, potentially also facilitating the spread of languages and certain phenotypic traits. We investigated this by using new, improved methods to sequence low-coverage genomes from 101 ancient humans

Aging studies for the ATLAS Transition Radiation Tracker (TRT)

A summary of the aging and material validation studies carried out for the ATLAS Transition Radiation Tracker (TRT) is presented. Particular emphasis is put on the different phenomena observed in straw tubes operating with the chosen Xe/CF4/CO2 mixture. The most serious effects observed are silicon deposition on the anode wire and damage of the anode wire gold plating. Etching phenomena and active

Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).

BACKGROUND: It is widely believed that cancer can be prevented by high intake of fruits and vegetables. However, inconsistent results from many studies have not been able to conclusively establish an inverse association between fruit and vegetable intake and overall cancer risk. METHODS: We conducted a prospective analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC)

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

BACKGROUND: Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.METHODS: We used data from 4,325 BRCA1 and 2,568 BRCA2 mutation carriers to analyze the pathology of invasive breast, ovarian, and contralateral breast cancers.RESULTS: There was strong evidence t

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Filosofins historia: Tentamen (100 poäng) Höst 2025 G: 50-74 poäng VG: 75-100 poäng OBS! Skriv dina svar så tydligt som möjligt. Det är diF ansvar aF se Gll aF läraren kan läsa din handsGl. Tema 1: FörsokraGker Gll Aristoteles (25 poäng) Fråga 1.1 (välj endast en fråga av a och b; svara med 5 Gll 10 rader; 5 poäng) a) Redogör för Anaximandros apeiron b) Redogör för Parmenides ’det varande’ Fråga 1

https://www.ht.lu.se/media/utbildning/dokument/kurser/FTEA13/20261/Exempeltentor_VT26_teoretisk_filosofi_grundkurs.pdf - 2026-05-21

Arbets- och miljömedicin

Arbets- och miljömedicin | Lund Ar be ts - oc h m ilj öm ed ic in S yd Rapport nr 18/2017 Åtgärdsnivåer mot belastningsskada Inger Arvidsson Ergonom, Dr Med Vet Camilla Dahlqvist Biomedicinsk analytiker, doktorand Henrik Enquist Civilingenjör, Tekn Dr Catarina Nordander Överläkare, docent Arbets- och miljömedicin Syd 2017-11-13 1 http://www5.lu.se/upload/GrafiskProfil/Logotyper/Lunds_universitet_C

https://www.vetenskaphalsa.se/wp-content/uploads/2023/10/Atgardsnivaer-mot-belastningsskada.pdf - 2026-05-28

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Filosofins historia: Tentamen (100 poäng) Höst 2025 G: 50-74 poäng VG: 75-100 poäng OBS! Skriv dina svar så tydligt som möjligt. Det är diF ansvar aF se Gll aF läraren kan läsa din handsGl. Tema 1: FörsokraGker Gll Aristoteles (25 poäng) Fråga 1.1 (välj endast en fråga av a och b; svara med 5 Gll 10 rader; 5 poäng) a) Redogör för Anaximandros apeiron b) Redogör för Parmenides ’det varande’ Fråga 1

https://www.fil.lu.se/media/utbildning/dokument/kurser/FTEA13/20261/Exempeltentor_VT26_teoretisk_filosofi_grundkurs.pdf - 2026-05-28

Oki-jesper andersson luca candiani jacob loefving

Inledning Avfallstudie - kring effektivt kunddeltagande Jesper Andersson Luca Candiani Jacob Löfving Handledare: Kurs SMKK01 Hervé Corvellec Kandidatuppsats Vt 2011 2 Förord Vi vill tacka vår handledare Hervé Corvellec för hans hjälp och hans kunskap i ämnet. Annika Owesson på Stadsbyggnadsförvaltningen Renhållningsverket och Jenny Westin på Avfall Sverige tackas även för att de ställt upp och sva

https://www.ses.lu.se/sites/ses.lu.se/files/oki-jesper_andersson_luca_candiani_jacob_loefving.pdf - 2026-05-29

MDC CV 2007-2012 - all variables

MDC CV rescreening 2007-2012: QuestionnaireContents Factors which are likely to have an effect on the emergence of cancer and cardiovascular diseases, such as occupation, physical activity, psychosocial environment, tobacco and alcohol consumption, health, diseases in the family, etc. Other variables are questions about PSA test (only men), hormonal replacement therapy and mammographic screening (

https://www.malmo-kohorter.lu.se/malmo-kost-cancer-mkc/datainsamling-mkc/mdc-cv-2007-2012-all-variables - 2026-05-29

Bilaga till ansökan, KPU VT 2022

Bilaga till ansökan, KPU VT 2022 LUNDS UNIVERSITET lnsitutionen för utbildni ngsvetenskap Bilaga till ansökan, KPU Du ansöker till utbildningen via ditt konto på antagning.se Om du inte har ett konto ska du först skapa ett. I samband med din ansökan till utbildningen fyller du också i detta formulär och laddar upp på antagning.se senast sista anmälningsdag. Aktuella anmälningsdatum hittar du på de

https://www.uvet.lu.se/fileadmin/user_upload/uvet/lararutbildning/pdf/Bilaga_till_ansoekan__KPU_VT_2024_.pdf - 2026-04-20

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1 LIVA14/LIVB10, delkurs 3: Från barocken till romantiken. Litteraturhistorisk översiktskurs HT 2023 Lärare: Erik Zillén (erik.zillen@litt.lu.se) Dag Tid & sal Moment Fr 27/10 10–12, A129b Litteratur och historia. Barocken Att läsa: Rosendahl Thomsen 2015 – LHV, s. 203–209 Må 30/10 Barockpoesi 10–12, L201 grupp LIVA14 13–15, L201 grupp LIVB10 Att läsa: dikter av Donne, Bradstreet, Gryphius, Queved

https://www.sol.lu.se/media/utbildning/dokument/kurser/LIVB10/20232/LIVA14_LIVB10_dk3_anvisningarHT2023_1.pdf - 2026-05-04

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1 LIVA04, delkurs 3: Från barocken till romantiken. Litteraturhistorisk översiktskurs HT 2022 Lärare: Erik Zillén (erik.zillen@litt.lu.se) Dag Tid & sal Moment Må 31/10 10–12, C337LUX Litteratur och historia. Barocken Att läsa: Rosendahl Thomsen 2015 – LHV, s. 203–209 Ti 1/11 Barockpoesi 10–12, H405 grupp A 13–15, L403 grupp B Att läsa: dikter av Donne, Bradstreet, Gryphius, Quevedo och Sor Juana

https://www.sol.lu.se/media/utbildning/dokument/kurser/LIVA04/20222/LIVA04_3_anvisningarHT2022_1.pdf - 2026-05-04

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1 LUNDS UNIVERSITET Institutionen för arkeologi och antikens historia _______________________________________________________________________________________________________________________________________________________ Kurslitteratur för ARKD06, 15 000 år i Skåne – en kulturhistoria, 15 hp Fastställd av institutionsstyrelsen 2023-06-07 Litteraturen söks i LUBcat och/eller LUBsearch om inget ann

https://www.ht.lu.se/media/utbildning/dokument/kurser/ARKD06/20242/ARKD06_litteraturlista_230607.pdf - 2026-05-24