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A prototype of the Transition Radiation Tracker (TRT) for the ATLAS experiment at the CERN LHC has been built and tested at the CERN SPS. Detailed studies of the drift-time measurements, alignment technique, hit registration efficiency, track and momentum accuracy were performed. A coordinate measurement accuracy of 150 Pin for a single TRT drift tube and momentum resolution of 0.8% for 20 GeV pio
Popular Abstract in English As far as we know the Northern Fulmar (just referred to as Fulmar from her on), did not start breeding on the Faroe Islands before about 150 years ago. But it has been known by the Faroese for a long time. Mainly as a bad omen and according to folklore fishermen would return home if they encountered Fulmars when out at sea, since they believed it was the bringer of storThe Northern Fulmar (Fulmarus glacialis) is one of the most abundant seabirds in the Northern Hemisphere and the most abundant seabird on the Faroe Islands. Except from a few sporadic observations up until the 1950´s no study has focused on this species on the Faroe Islands. Being considered a significant consumer of marine resources in the Faroese marine ecosystem a closer study of this species´
Popular Abstract in English Disasters continue to affect urban populations and housing infrastructure. They are intensified by extreme weather events caused by climate change. This situation has made the creation of synergies between climate change adaptation (CCA) and disaster risk management (DRM) urgent. Despite their similarities and the recognised need to unite CCA and DRM efforts, the fieldsAn increasing number of disasters continue to affect urban populations and housing infrastructure. The overwhelming majority of them have been caused by climate-related events. This situation has made the creation of synergies between climate change adaptation (CCA) and disaster risk management (DRM) urgent. Despite the recognised need to unite CCA and DRM efforts, the fields remain separate. Furt
Popular Abstract in English A handful of diseases-causing pathogenic microorganisms claim millions of lives worldwide each year, mainly due to limited diagnostic capabilities. The lack of simple, cost-effective, sensitive and rapid on-site diagnostic tools lead to delays in the diagnoses with a subsequent lag in treatment, which in turn can result in serious complications or even loss of lives. Fast and sensitive detection of pathogenic microbial cells is a highly important task in medical diagnostics, environmental analysis and evaluation of food safety. Accordingly, the idea of microorganism identification by the recognition of specific DNA sequence using electrochemical technique is one of the leading researches in the development of diagnostic devices. In other words, it should only
BACKGROUND: The major factors individually reported to be associated with an increased frequency of CDKN2A mutations are increased number of patients with melanoma in a family, early age at melanoma diagnosis, and family members with multiple primary melanomas (MPM) or pancreatic cancer. METHODS: These four features were examined in 385 families with > or =3 patients with melanoma pooled by 17 Gen
High-spin states of the neutron deficient (100)pd nucleus have been investigated via the Cr-50(Ni-58, 4p alpha) and Zn-70(S-36,6n) heavy-ion induced reactions. For the detection of evaporated particles and gamma rays the NORDBALL array equipped with ancillary detectors and the EUROGAM II detector system were utilized. By the use of in-beam spectroscopic methods 89 transitions belonging to (100)pd
Popular Abstract in English Every year, Sweden produces 1.5 million tons of incineration residues from waste to energy plants. Among these residues bottom ash(BA) due to its large volume and good geotechnical quality can be reused as an alternative construction material. However there are some negative environmental impacts of this practice such as leaching of salts and metals to soils and groundwEvery year, Sweden produces 1.5 million tons of incineration residues from waste to energy plants. Among these residues bottom ash(BA) due to its large volume and good geotechnical quality can be reused as an alternative construction material. However there are some negative environmental impacts of this practice such as leaching of salts and metals to soils and groundwater. Environmental processe
Popular Abstract in Swedish Proteoglykaner (PG), framför allt sådana som bär glykosaminoglykan-sidokedjor av heparansulfat (HS) typ, utgör multifunktionella receptorer på cellytan och i pericellulär matrix hos alla adherenta celler i högre organismer. HS-proteoglykaner är inblandade i många olika cellprocesser, bl.a. koagulation, celltillväxt, och aktivering av enzymer, antienzymer samt bindning tThe present investigation focuses on the role of HS metabolism in cell proliferation. The effect of the HS priming ß-D-xyloside, 2-(6-hydroxynaphthyl)-O-ß-D-xylopyranoside (Xyl-2-Nap-6-OH) on the proliferation of normal and transformed cells was studied. Xyl-2-Nap-6-OH inhibited growth of transformed cells to a significantly greater extent than normal cells. The growth inhibition exerted by the xy
Popular Abstract in Swedish Vi är omringade av olika mikrorganismer såsom bakterier och svampar. Bakterier kan leva från de mest ogästvänliga miljöer som arktisk is och varma källor på havsbotten till varje människas hud och mag- tarmkanal. Bakterier som bor på och inuti oss spelar en stor roll i vårt välbefinnande. De hjälper oss att smälta maten och hindrar andra mer farliga bakterier från att bAssociation to specific host tissue structures allows pathogenic bacteria to establish an infection and facilitates the spread within its host. Interactions between bacterial surface structures and human proteins might determine the outcome of the infection. Streptococcus pyogenes (S. pyogenes), is a human pathogen mostly causing localized infections of the skin and respiratory tract, but it is al
Popular Abstract in Swedish Typ 2 diabetes är en sjukdom där dels bukspottkörtelns förmåga att producera hormonet insulin och dels kroppens förmåga att svara på insulin (insulinkänslighet) är nedsatt. Eftersom insulin behövs för att ta upp socker (glukos) från blodet i organ som muskel och fett, är glukoskoncentrationen i blodet förhöjd hos typ 2 diabetiker. Med hjälp av olika behandlingar såsom dCardiovascular complications are frequent in type 2 diabetes (T2D) and cardiovascular death is the most common cause of death for these individuals. A region on chromosome 19 (19q13) has been indicated by several genome scans as a susceptibility locus for T2D or components of the metabolic syndrome (MetS). This gene rich region contains the gene encoding muscle glycogen synthase (GYS1), earlier as
Compared to food patterns, nutrient patterns have been rarely used particularly at international level. We studied, in the context of a multi-center study with heterogeneous data, the methodological challenges regarding pattern analyses.
OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is commonly diagnosed at an advanced stage. Liquid biopsy approaches may facilitate detection of early stage PDAC when curative treatments can be employed.DESIGN: To assess circulating marker discrimination in training, testing and validation patient cohorts (total n=426 patients), plasma markers were measured among PDAC cases and patients with ch
Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more
BACKGROUND: The European registry for minimally invasive pancreatic surgery (E-MIPS) collects data on laparoscopic and robotic MIPS in low- and high-volume centers across Europe.METHODS: Analysis of the first year (2019) of the E-MIPS registry, including minimally invasive distal pancreatectomy (MIDP) and minimally invasive pancreatoduodenectomy (MIPD). Primary outcome was 90-day mortality.RESULTS
Two of the key functions of arteries in the brain are (1) the well-recognized supply of blood via the vascular lumen and (2) the emerging role for the arterial walls as routes for the elimination of interstitial fluid (ISF) and soluble metabolites, such as amyloid beta (Aβ), from the brain and retina. As the brain and retina possess no conventional lymphatic vessels, fluid drainage toward peripher
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across diverse modalities facing these problems have designed a format specification process (OME-NGFF) to address these needs. This paper brings together a wide range of those c
PURPOSE: Invasive lobular carcinoma (ILC) is a subtype of breast cancer accounting for 10% of breast tumors. The majority of patients are treated with endocrine therapy; however, endocrine resistance is common in estrogen receptor-positive breast cancer and new therapeutic strategies are needed. Bromodomain and extraterminal inhibitors (BETi) are effective in diverse types of breast cancer but the
The medial temporal lobe (MTL) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as Alzheimer's disease neurofibrillary tau tangles. The MTL cortex is composed of several subregions which differ in their functional and cytoarchitectonic features. As neuroanatomical schools rely on different cytoarchitectonic definition
