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I takt med både vägnätets expansion och trafikbelastningens ökning på vägarna blir det viktigare att mäta och analysera vägars bärighet samt spårdjupsutveckling. Ökad trafikbelastning, särskilt från tung trafik, påskyndar effekten av vägars nedbrytning. Denna trafikökning beror framför allt på näringslivets utveckling och har resulterat i att vägarna utsätts för mer belastning än vad de är dimensiAs the road network expands and traffic load increases, accurate measurement and analysis of road bearing capacity and rut depth development become more important. Increased traffic load accelerates road degradation, leading to bearing capacity deficiencies. Regular maintenance is crucial to avoid high costs. This study investigates the relationship between bearing capacity and rut depth developme

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BACKGROUND: Proximal humeral fracture (PHF) is the fourth most common nonspinal fracture in adults. The long-term clinical outcomes after nonoperative treatment for different PHF types are unclear. This study aims to evaluate the long-term clinical outcomes of a nonoperatively treated PHF across various fracture types using the Neer and Arbeitsgemeinschaft für Osteosynthesefragen (AO) classificati

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There is a need to transform the urban mobility regime to mitigate climate change and improve living quality in cities. Cargo bikes (CBs) offer a promising solution to replace motorized vehicles, especially for last-mile deliveries and private logistics. They show considerably lower carbon intensity, occupy less space and help reduce air and noise pollution in cities. CB sharing relieves individua

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BACKGROUND: Information on cancer prevalence is of major importance for health planning and resource allocation. However, systematic information on cancer prevalence is largely unavailable. MATERIALS AND METHODS: Thirty-eight population-based cancer registries from 17 European countries, participating in EUROPREVAL, provided data on almost 3 million cancer patients diagnosed from 1970 to 1992. Sta

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Intracellular lipolysis is a major pathway of lipid metabolism that has roles, not only in the provision of free fatty acids as energy substrate, but also in intracellular signal transduction. The latter is likely to be particularly important in the regulation of insulin secretion from islet beta-cells. The mechanisms by which lipolysis is regulated in different tissues is, therefore, of considera

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Following systemic injection, hematoporphyrin derivative (HPD) is known to be selectively retained in malignant tissue. This property can be used in a two-fold way: a) for localizing tumours by observing the characteristic dual-peaked laser-induced fluorescence from HPD, and b) for photodynamic therapy (HPD-PDT) using a localized HPD-assisted singlet oxygen release induced by irradiation of 630 nm

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BACKGROUND: It is not known if modifiable lifestyle factors that predict survival after invasive breast cancer differ by subtype.METHODS: We analyzed data for 121,435 women diagnosed with breast cancer from 67 studies in the Breast Cancer Association Consortium with 16,890 deaths (8,554 breast cancer-specific) over 10 years. Cox regression was used to estimate associations between risk factors and

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BackgroundThe Parkinson's Disease (PD) Home Diary (HD) is a common clinical outcome measure, but studies show only fair agreement between clinical observer and patient assessments, with no significant improvement after patient training.ObjectivesTo investigate the agreement between a clinical observer and relatives of PD patients when assessing the patient's motor status in the HD. Agreement was a

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OBJECTIVES: Low or high sympatho-adrenal-medullary axis (SAM) and hypothalamic-pituitary-adrenal axis (HPA) dysregulation reflect chronic stress. Retinal vessel dynamics may relate to SAM, HPA activity and stroke risk. Our objectives were therefore to assess the relationships between retinal vessel, SAM and HPA responses, and to determine stroke risk.METHODS: A prospective bi-ethnic gender cohort

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Available tools for prostate cancer (PC) prognosis are suboptimal but may be improved by better knowledge about genes driving tumor aggressiveness. Here, we identified FRMD6 (FERM domain-containing protein 6) as an aberrantly hypermethylated and significantly downregulated gene in PC. Low FRMD6 expression was associated with postoperative biochemical recurrence in two large PC patient cohorts. In

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Popular Abstract in Swedish För att tillverka en pappersbaserad förpackning är det viktigt att materialet är tillräckligt hållfast. Förpackningsmaterial består ofta av kartong, aluminium och polymerfilmer där kartong utgör den största delen av förpackningen och bidrar mest till styvheten. Det säljs årligen mer än hundra miljarder förpackningar i världen och om kostnaden samt materi- alåtgång för aContinuum based elasto-plastic-damage models for paperboard have been established in this work. The thesis begins with an introductory section that describes the mechanical properties of paperboard and some of the converting processes during forming of a package. A short review of modeling concepts that have been applied to paperboard is presented and then some key aspects and assumptions develope

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The effect of 5% low-methoxylated pectin, high-methoxylated pectin, and guar gum on 1,2-dimethylhydrazine initiation of colon cancer was investigated using groups of 30 rats. The growth of the rats in the different groups was very similar to that of control group fed a fiber-free diet. Both kinds of pectin increased the multiplicity of color tumors, whereas guar gum did not significantly influence

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The aim of this study is to evaluate a new pedagogic approach implemented in a compulsory materials course for product design students at bachelors level at ABC University. When developing a new curriculum for the material course, a decision was made to teach materials and production methods in a contextualized setting with emphasis on how students can deal with materials in a design process. Meth

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Lera består utav små finkorniga lermineraler, vilka utgörs till stor del av elektrostatiskt laddade nanopartiklar, även kallade lerplattor. En lerplatta har en tjocklek på en miljarddels meter och dess diameter kan variera alltifrån fem till tusen gånger större än tjockleken, vilket kan jämföras med ett A4-ark, där kortsidan är tusen gånger större än tjockleken. Denna storleksskillnad ger upphov tClay minerals consist of anisotropic nanoplatelets where the majority of the clay minerals are highly charged, and thus, swell in aqueous solution. The structure and swelling depend on the type of clay mineral, and also on the ionic composition, and temperature. The natural clay mineral montmorillonite have been studied both theoretically and experimentally. Theoretically, coarse-grained models ha

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The MAXIV injector has two guns - a thermionic used for ring injections, and a photocathode used for short pulse facility operation. A commercial Ti:sapphire laser from KMLabs drives the copper based photocathode gun. It has been running without major issues for more than 3 years. The laser delivers up to §I{500}{\textmu J} on the cathode at the third harmonic, §I{263}{nm}, via a vacuum laser tran

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A motivation for the development of a versatile, programmable source of shaped picosecond pulses for use in photocathode electron gun preinjectors is presented. We present the experimental setup for arbitrary longitudinal pusle shaping of the MAX IV photocathode gun laser. The setup consists of a grating-based Fourier-domain shaper capable of stretching the pulses directly in the UV domain. Prelim

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Based on previous observations of the diurnal variation of urinary cystine excretion, the use of separate day and night urine collections was proposed. To improve the medical treatment of patients with cystinuria, this strategy was performed to guide the fluid intake and the administration of SH compounds (tiopronin, D-penicillamine, and MESNA).Twenty-six patients (19 treated with SH compounds and