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Introduction: Ovarian cancer is a lethal disease with low survival rates for women diagnosed in advanced stages. Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer

I september 2022 blev den elev som dödat två lärare på Malmö Latinskola den första 18-åringen att dömas till livstids fängelse. Tova Bennet, juris doktor i straffrätt, menar att målet har flera aspekter som kan motivera en prövning i högsta instans.

This article critically examines the dual role of the Georgian Orthodox Church (GOC) as both a cultural guardian of national identity and a barrier to covenantal pluralism in Georgia. Drawing on legal-financial and comparative-historical analysis, it demonstrates how the GOC’s institutional dominance perpetuates systemic inequalities, including disproportionate state funding, inequitable property

Adopting technological innovations is crucial for organizations to survive in dynamic and competitive market scenarios. Moreover, it is essential to understand the customer needs and respond accordingly. The present research makes use of Technology-Organization-Environment (TOE) framework for Lean Six Sigma Integrated Industry 4.0 (LSSI) adoption. Scholarly literature shows that adopting LSSI dras

In this thesis, we provide a number of novel algebraic means of certifying stability and performance for linear systems constrained in various ways by cones. The purpose is mainly threefold: to provide mathematical statements with applicative potential, to unify seemingly dissimilar results in the literature and thereby increase understanding, and to advance the state of the art on dynamical syste

Beyond 5G/6G communication systems promise to significantly impact the development of a New Generation of CCAM. Reconfigurable Intelligent Metasurfaces (RIM) are by now established as a key enabling technology for 6G Systems. They have been extensively investigated the last few years, as they possess exotic properties allowing for precise control over any aspect of an impinging wave. As such, they

This paper gives a global solution to an H-infinity control problem for systems with symmetric state matrix and state-dependent input matrix. A simple, closed-form expression for the minimizing controller is obtained. This is in contrast to already established theory in which nonlinear H-infinity problems are solved locally. The result is then illustrated through an example, and the potential for

Background and study aims Endoscopic submucosal dissection (ESD) allows en bloc resection of large colorectal lesions but ESD experience is limited outside Asia. This study evaluated implementation of ESD in the treatment of colorectal neoplasia in a Western center. Patients and methods Three hundred and one cases of colorectal ESD (173 rectal and 128 colonic lesions) were retrospectively evaluate

Infections with Human papillomavirus type 16 (HPV16) is the most the most common, sexually transferred and is responsible for genital warts, cervical cancers and a growing number of head and neck cancers. Knowledge about how HPV16 interacts with the infected cell to regulate its gene expression is essential for therapeutic development. Here, we show that the viral E5 protein which may contribute t

Inflammation is a vital response and necessary for maintaining homeostasis. Inflammation protects against tissue damage and pathogens-but is also one of the main driving forces of the atherosclerotic plaque progression. How and why the inflammatory response is initiated in the atherosclerotic disease is not fully known, but evidence suggests modified lipids as potential antigens activating the imm

Lignocellulose from terrestrial plant biomass is abundant and contains polymeric carbohydrates and lignin; both recognized as attractive renewable feedstocks for energy, chemicals and materials as alternatives to fossils to meet the targets for future sustainable development. Liquid biofuels are particularly important renewable commodities because of the vast infrastructure already in place to use

Catholics and Protestants assumed that God instituted the family and that it had certain spiritual functions to perform. In 1985, Colleen McDannell addressed changes in Christian perceptions of the home and family in nineteenth-century America. This chapter focuses on Christian ideas of the home and family in nineteenth-century Europe and touches on similar themes to those discussed by McDannell,

Studies of spatial behavior increasingly rely on a combination of audiovisual and geospatial recordings. So far, however, few analytical environments have offered opportunities for integrated and expedient annotation and analysis of the two. Here we report the first study aimed at integrating geospatial data in ELAN, a tool developed for time-aligned annotation of audiovisual media. By calibrating

Telomeres form the end segment of the DNA helix and shorten with every cell division until getting so short that the cell stops dividing and will undergo programmed cell death (apoptosis). Research has supported the view that telomere length could be regarded as a marker of biological aging, even if methodological problems could interfere with the interpretation of telomere length in cross-section

Study Objectives: To determine the effect of continuous positive airway pressure (CPAP) treatment on health-related quality of life (HRQoL) in adults with coronary artery disease (CAD) and nonsleepy obstructive sleep apnea (OSA). Methods: This was a secondary outcome analysis of the RICCADSA trial, conducted in Sweden between 2005 and 2013. Adults with CAD, nonsleepy OSA (apnea-hypopnea index [AHI

Background: Due to advances in hip arthroscopy, the number of surgical procedures has increased dramatically. The diagnostic challenge in patients with longstanding hip and groin pain, as well as the increasing number of hip arthroscopies, may lead to a higher number of patients referred to tertiary care for consideration for surgery. Therefore, the aims were: 1) to describe the prevalence of hip-