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Optical Studies of Polytypism in GaAs Nanowires

Semiconductor nanowires are often regarded as having potential to be building blocks for novel applications. Their geometry allows defect-free combinations of materials that have a high degree of lattice mismatch. III-V semiconductor nanowires can also be grown in the wurtzite crystal phase, which is not stable in bulk material or thin films. The atomic arrangement differs between wurtzite and zin

Evolution of olfaction in Lepidoptera and Trichoptera : Gene families and antennal morphology

Resultaten i denna avhandling ökar vår kunskap om hur evolutionen av feromondetektering hos fjärilar gått till.Luktsinnet är viktigt för de flesta djur, inklusive människor, hundar, insekter och många andra. Hos insekter, särskilt nattfjärilar och flugor, används luktsinnet för att hitta parningspartners, föda, äggläggningsställen och att undkomma fiender.Feromoner är kemikalier som produceras ochIn moths, females produce sex pheromone compounds to attract males over a long distance for mating. The antennae of moths and many other insects have specialized odorant receptors (ORs), called pheromone receptors (PRs), to sense the pheromone compounds and they group in a monophyletic clade (PR clade).In this thesis, I investigated and compared various components of the olfactory system in differ

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcription factors during adaptation to the hypoxic tumor microenvironment. Deletion analyses of the two key HIF isoforms found that HIF-1α, but not HIF-2α, was essential for the effector state in CD8+ T cells. Furthermore, loss of HIF-1α in CD8+ T cells reduced tumor infiltration and tumor cell killing, and altered tumor vascular

Lymph node metastases as only qualifier for stage IV serous ovarian cancer confers longer survival than other sites of distant disease – a Swedish Gynecologic Cancer Group (SweGCG) study

Background: The International Federation of Gynecology and Obstetrics (FIGO) ovarian cancer staging system includes no sub-stage for lymph nodes (LN) as only distant disease manifestation. We explore the prognostic implication of LN as only stage IV classifier in serous ovarian cancer. Method: This is a nation-wide, population-based study on 551 women with serous stage IV cancers diagnosed between

Perinatal and familial risk factors for irritable bowel syndrome in a Swedish national cohort

Objective: Studies of the importance of perinatal factors for the development of irritable bowel syndrome (IBS) are sparse. We conducted a large national cohort study to examine perinatal and familial risk factors for IBS. Material and methods: A national cohort of 1,963,685 persons who were born in Sweden in 1973–1992 (identified from the Swedish Birth Registry) were followed up for adult (18 yea

Management of community-acquired pneumonia in immunocompetent adults : updated Swedish guidelines 2017

Based on expert group work, Swedish recommendations for the management of community-acquired pneumonia in adults are here updated. The management of sepsis-induced hypotension is addressed in detail, including monitoring and parenteral therapy. The importance of respiratory support in cases of acute respiratory failure is emphasized. Treatment with high-flow oxygen and non-invasive ventilation is

Yoga – a laborious way to well-being : patients’ experiences of yoga as a treatment for hypertension in primary care

Objective: The aim of the study was to describe patients’ experience of yoga as a treatment for hypertension, as well as their experience of living with hypertension. Design: Qualitative interview study Method and materials: In 2013–2014, in southern Sweden, patients with hypertension from three health care centres were invited to participate in a randomised controlled trial on yoga for hypertensi

MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles

MicroRNAs contribute to the maintenance of optimal cellular functions by fine-tuning protein expression levels. In the pancreatic β-cells, imbalances in the exocytotic machinery components lead to impaired insulin secretion and type 2 diabetes (T2D). We hypothesize that dysregulated miRNA expression exacerbates β-cell dysfunction, and have earlier shown that islets from the diabetic GK-rat model h

Density Measurements of CO2-Expanded Liquids

Novel experimental data of density for mixtures containing CO2 + ethanol, CO2 + ethyl lactate, CO2 + glycerol + ethanol, and CO2 + glycerol + ethyl lactate at low/moderate temperatures (308 and 323 K), pressures between 5 and 30 MPa, and high amounts of the organic solvent (molar fraction x = 0.5-0.9) are presented. The chosen organic solvents (ethanol, ethyl lactate, and glycerol) are green and a

How are biodiversity and dispersal of species affected by the management of roadsides? A systematic map

Background: In many parts of the world, roadsides are regularly managed for traffic-safety reasons. Hence, there are similarities between roadsides and certain other managed habitats, such as wooded pastures and mown or grazed grasslands. These habitats have declined rapidly in Europe during the last century. For many species historically associated with them, roadsides may function as new primary

Asthma symptoms, mannitol reactivity and exercise-induced bronchoconstriction in adolescent swimmers versus tennis players

Background: Strenuous physical activity at an elite level is associated with an increased risk for asthma and, in some sports, also prevalence of allergies. The aim of this study was to investigate the prevalence of asthma and allergy among elite swimmers and tennis players and compare airway hyperreactivity to mannitol and exercise. Materials and methods: One hundred and one adolescent swimmers a

Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions

Integrins are transmembrane receptors that, upon activation, bind extracellular ligands and link them to the actin filament (F-actin) cytoskeleton to mediate cell adhesion and migration. Cytoskeletal forces in migrating cells generated by polymerization- or contractility-driven “retrograde flow” of F-actin from the cell leading edge have been hypothesized to mediate integrin activation for ligand

Modelling over-hygroscopic wood sorption isotherms based on quantitative wood anatomy

A sorption isotherm expresses the relation between ambient relative humidity (RH) and equilibrium moisture content of a material for a specific temperature. The sorption isotherm can generally be divided into a hygroscopic part covering low, medium and high RH levels, and an over-hygroscopic part close to 100% RH. For wood, the hygroscopic part is dominated by water uptake in cell walls and the ov

Empathy in Social Work

A dominant conceptualization of empathy in social work practice and education, provided by Karen Gerdes and Elizabeth Segal, relies heavily on the simulation theory adopted directly from the cognitive neurosciences. The aim was to critically challenge such a view by reporting on some recent empirical findings from the field in which professional social workers were interviewed about their experien

Can δD and δ18O stable isotopes be used to detect long-range dispersal among carabid beetles?

We studied if hydrogen (δD) and oxygen (δ18O) stable isotope values in three common carabid species in intensively managed agricultural landscapes in southernmost Sweden indicate long-range dispersal. We matched “emerging” (emergence tents) and “colonizing” (pitfall traps) individuals of three carabid species (Trechus quadristriatus, Harpalus rufipes, Pterostichus melanarius) to account for spatia

From values to probabilities

According to the fitting-attitude analysis of value (FA-analysis), to be valuable is to be a fitting object of a pro-attitude. In earlier publications, setting off from this format of analysis, I proposed a modelling of value relations which makes room for incommensurability in value. In this paper, I first recapitulate the value modelling and then move on to suggest adopting a structurally simila

Scrapping programmes and ITQs : Labour market outcomes and spill-over effects on non-targeted fisheries in Sweden

Scrapping programmes and individual transferable quotas (ITQs) are two management measures frequently used to reduce overcapacity in fisheries. These measures are often aimed at specific vessel segments targeting specific fish stocks. In this case, fishermen who scrap their vessels or sell their quotas may shift their fishing activities, possibly contributing to overcapacity in other fleets. The a

Microtextural Inheritance on Quartz Sand Grains from Pleistocene Periglacial Environments of the Mazovian Lowland, Central Poland

Sand grains from Quaternary glacial, aeolian and fluvial deposits in the Mazovian Lowland, central Poland, were examined to characterize the effects of different Quaternary processes on sand-grain surfaces that experienced repeated cycles of intense polar-desert-like conditions during the Middle and Late Pleistocene. A cold, dry and windy periglacial environment prevailed here at least twice betwe